Protein Alignment Hsp70Bbb and hspa12a

DIOPT Version :10

• Sequence 1: NP_788663.1
• Gene: Hsp70Bbb / 50022
• FlyBaseID: FBgn0051354
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001417784.2
• Gene: hspa12a / 751725
• ZFINID: ZDB-GENE-031001-1
• Length: 670
• Species: Danio rerio
• Alignment Length: 669
• Identity: 134/669 - (20%)
• Similarity: 225/669 - (33%)
• Gaps: 224/669 - (33%)

  Fly    19 QHGKVEIIANDQGNRTTPSYVAFTDSERLI--------GDP-AKNQ-----VAMNPRNTVFDAKR 69
            :|..|.::|.|.|..::....|||.....|        ||| ..||     :.:.| :..|.:..
Zfish    49 RHHFVVVVAIDFGTTSSGYAYAFTKEPECIHTMRRWEGGDPGVSNQKTPTTILLTP-DKKFHSFG 112

  Fly    70 LIGRKYDDPKIAEDMKHW----PFKV---------------VSDGGKPKIGVEYKGESKRFAPEE 115
            ...|.:.......:.|.|    .||:               .::|.|.| .::....:..|..|:
Zfish   113 YAARDFYHDLDPTESKQWLYLEKFKMKLHTTANLSIDTDLHAANGKKVK-ALDIFAYALAFFKEQ 176

  Fly   116 ISSMVLTKMKETAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGL------NVLRIINEPT 174
                .|.::.:.|.|....:....||||||.:....:|..::|.:.|.|      :.|.|..||.
Zfish   177 ----ALKELSDQAGAEFDNADVRWVITVPAIWKMPAKQFMREAAYKAALVTRENPDQLIIALEPE 237

  Fly   175 AAAL--------------------AYGLDKN---------------------------------L 186
            ||::                    .|....|                                 |
Zfish   238 AASIYCRKLRLHQMVDLGSKTALNGYSPTDNAGVGMTQAKEHVRRNRQSRTFLVENVIGELWSEL 302

  Fly   187 KDERNVLIFDLGGGTFDVSI--LTIDEGSLFEVRSTAGDTH--LGGE-DFDNRLVTHLAEEFKRK 246
            .:....::.|.||||.|:::  :.:.||.|.|:...:|..:  :|.: :|:..|.....::|..:
Zfish   303 AEGDRYVVVDCGGGTVDLTVHQIRLPEGHLKELYKASGGPYGSIGIDYEFEKLLCKIFGQDFIDQ 367

  Fly   247 YKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKV-----------SRARF 300
            :|   ...|.|...|..|.|..||..:......:.|:..|...|:|.|.           |...|
Zfish   368 FK---IKRPAAWVDLMIAFESRKRAATPDRSNPLNINLPFSFIDYYKKFRGHSVEHALRKSNVDF 429

  Fly   301 EELCAD------------LFRNTLQPVEKALNDAKMDKGQIHDI---VLVGGSTRIPKVQSLLQE 350
            .:..:.            ||:.|:..:.:.|.:. .|:.::.||   .||||....|.:|..:|.
Zfish   430 VKWSSQGMLRMSPDAMNALFKPTIDHIIQHLTEL-FDRPEVTDIKFLFLVGGFAESPLLQQAVQN 493

  Fly   351 FFHGKNLNLSINPDEAVAYGAAVQAAILSG-DQSGKIQDVLLVDVAPLSLGIETAGGVMTKLIE- 413
            ...|:: .:.|..|..:   ..::.|:|.| |.|     ::.|..:||:.|:    ||:.:.:|
Zfish   494 MLQGRS-RIIIPHDVGL---TILKGAVLFGLDPS-----IIKVRRSPLTYGV----GVLNRFVEG 545

  Fly   414 -------------RNCRIPCKQTKTFSTY--------------------SDNQPGVSIQVYEGER 445
                         |.|      |..|.|:                    ..:|..:.|.||..|:
Zfish   546 KHPPEKMLVKDGMRWC------TDVFDTFISADQSVALGETVKRSYTPAKPSQQVIVIHVYCSEK 604

  Fly   446 AMTKDNNALGTF--------------DLSGI-PPAPRGVPQIEVTFDLDANGILNVSAKEMSTGK 495
            ...       ||              |:||. .||.|...|..:.|.       :...:.|:...
Zfish   605 ESV-------TFITDPGVRKCGSLKLDVSGTESPAARREIQTLMQFG-------DTEIRAMAVDV 655

  Fly   496 AKNITIKNDKGRLSQAEID 514
            |.:.|:|        |.||
Zfish   656 ATSRTVK--------ASID 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bbb	NP_788663.1	PTZ00009	2..641	CDD:240227	134/669 (20%)
hspa12a	NP_001417784.2	None