Protein Alignment Hsp70Bbb and hspa12a

DIOPT Version :9

• Sequence 1: NP_788663.1
• Gene: Hsp70Bbb / 50022
• FlyBaseID: FBgn0051354
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_017207164.1
• Gene: hspa12a / 751725
• ZFINID: ZDB-GENE-031001-1
• Length: 671
• Species: Danio rerio
• Alignment Length: 669
• Identity: 134/669 - (20%)
• Similarity: 225/669 - (33%)
• Gaps: 224/669 - (33%)

  Fly    19 QHGKVEIIANDQGNRTTPSYVAFTDSERLI--------GDP-AKNQ-----VAMNPRNTVFDAKR 69
            :|..|.::|.|.|..::....|||.....|        ||| ..||     :.:.| :..|.:..
Zfish    50 RHHFVVVVAIDFGTTSSGYAYAFTKEPECIHTMRRWEGGDPGVSNQKTPTTILLTP-DKKFHSFG 113

  Fly    70 LIGRKYDDPKIAEDMKHW----PFKV---------------VSDGGKPKIGVEYKGESKRFAPEE 115
            ...|.:.......:.|.|    .||:               .::|.|.| .::....:..|..|:
Zfish   114 YAARDFYHDLDPTESKQWLYLEKFKMKLHTTANLSIDTDLHAANGKKVK-ALDIFAYALAFFKEQ 177

  Fly   116 ISSMVLTKMKETAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGL------NVLRIINEPT 174
                .|.::.:.|.|....:....||||||.:....:|..::|.:.|.|      :.|.|..||.
Zfish   178 ----ALKELSDQAGAEFDNADVRWVITVPAIWKMPAKQFMREAAYKAALVTRENPDQLIIALEPE 238

  Fly   175 AAAL--------------------AYGLDKN---------------------------------L 186
            ||::                    .|....|                                 |
Zfish   239 AASIYCRKLRLHQMVDLGSKTALNGYSPTDNAGVGMTQAKEHVRRNRQSRTFLVENVIGELWSEL 303

  Fly   187 KDERNVLIFDLGGGTFDVSI--LTIDEGSLFEVRSTAGDTH--LGGE-DFDNRLVTHLAEEFKRK 246
            .:....::.|.||||.|:::  :.:.||.|.|:...:|..:  :|.: :|:..|.....::|..:
Zfish   304 AEGDRYVVVDCGGGTVDLTVHQIRLPEGHLKELYKASGGPYGSIGIDYEFEKLLCKIFGQDFIDQ 368

  Fly   247 YKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKV-----------SRARF 300
            :|   ...|.|...|..|.|..||..:......:.|:..|...|:|.|.           |...|
Zfish   369 FK---IKRPAAWVDLMIAFESRKRAATPDRSNPLNINLPFSFIDYYKKFRGHSVEHALRKSNVDF 430

  Fly   301 EELCAD------------LFRNTLQPVEKALNDAKMDKGQIHDI---VLVGGSTRIPKVQSLLQE 350
            .:..:.            ||:.|:..:.:.|.:. .|:.::.||   .||||....|.:|..:|.
Zfish   431 VKWSSQGMLRMSPDAMNALFKPTIDHIIQHLTEL-FDRPEVTDIKFLFLVGGFAESPLLQQAVQN 494

  Fly   351 FFHGKNLNLSINPDEAVAYGAAVQAAILSG-DQSGKIQDVLLVDVAPLSLGIETAGGVMTKLIE- 413
            ...|:: .:.|..|..:   ..::.|:|.| |.|     ::.|..:||:.|:    ||:.:.:|
Zfish   495 MLQGRS-RIIIPHDVGL---TILKGAVLFGLDPS-----IIKVRRSPLTYGV----GVLNRFVEG 546

  Fly   414 -------------RNCRIPCKQTKTFSTY--------------------SDNQPGVSIQVYEGER 445
                         |.|      |..|.|:                    ..:|..:.|.||..|:
Zfish   547 KHPPEKMLVKDGMRWC------TDVFDTFISADQSVALGETVKRSYTPAKPSQQVIVIHVYCSEK 605

  Fly   446 AMTKDNNALGTF--------------DLSGI-PPAPRGVPQIEVTFDLDANGILNVSAKEMSTGK 495
            ...       ||              |:||. .||.|...|..:.|.       :...:.|:...
Zfish   606 ESV-------TFITDPGVRKCGSLKLDVSGTESPAARREIQTLMQFG-------DTEIRAMAVDV 656

  Fly   496 AKNITIKNDKGRLSQAEID 514
            |.:.|:|        |.||
Zfish   657 ATSRTVK--------ASID 667

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bbb	NP_788663.1	PTZ00009	2..641	CDD:240227	134/669 (20%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	96/482 (20%)
hspa12a	XP_017207164.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810