Protein Alignment Hsp70Bbb and HSPA13

DIOPT Version :9

• Sequence 1: NP_788663.1
• Gene: Hsp70Bbb / 50022
• FlyBaseID: FBgn0051354
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_008879.3
• Gene: HSPA13 / 6782
• HGNCID: 11375
• Length: 471
• Species: Homo sapiens
• Alignment Length: 422
• Identity: 163/422 - (38%)
• Similarity: 246/422 - (58%)
• Gaps: 51/422 - (12%)

  Fly     4 IGIDLGTTYSCVGVY--QHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFD 66
            |||||||||..|||:  ..|||::|.::.|:.:.||.|:|||::..:|..:......||:||::|
Human    34 IGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNPQNTIYD 98

  Fly    67 AKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAY 131
            |||.||:.:...::..::..:||||::..|..:..|. ..|:...:||.:.|.:|.|:||.||||
Human    99 AKRFIGKIFTAEELEAEIGRYPFKVLNKNGMVEFSVT-SNETITVSPEYVGSRLLLKLKEMAEAY 162

  Fly   132 LGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKDERNVLIFD 196
            ||..:.:|||:|||.|:..||.:|.:|.::|||.:||:||||||||:||||.|  .|..:||:.|
Human   163 LGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMAYGLHK--ADVFHVLVID 225

  Fly   197 LGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRL 261
            |||||.|||:|. .:|.:|..|:.:|:..|||:||:.||:.:|.::..:.| ..:.|....:.||
Human   226 LGGGTLDVSLLN-KQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYKQIYQTY-GFVPSRKEEIHRL 288

  Fly   262 RTAAERAKRTLSSSTEATIEIDALFEGQD------------------------------------ 290
            |.|.|..|..|:....|.:.:....|.||
Human   289 RQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELPKDKLSSADDHRVNSGFGRGLSDKK 353

  Fly   291 -------FYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLL 348
                   |.|::||..|:.|..|||:..|.|:::.|.:..::|.:|.::||||||||||:::.::
Human   354 SGESQVLFETEISRKLFDTLNEDLFQKILVPIQQVLKEGHLEKTEIDEVVLVGGSTRIPRIRQVI 418

  Fly   349 QEFFHGKNLNLSINPDEAVAYGAAVQAAILSG 380
            |||| ||:.|.|::||.||..|.|:||.|..|
Human   419 QEFF-GKDPNTSVDPDLAVVTGVAIQAGIDGG 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bbb	NP_788663.1	PTZ00009	2..641	CDD:240227	163/422 (39%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	162/419 (39%)
HSPA13	NP_008879.3	HSPA13-like_NBD	12..463	CDD:212679	163/422 (39%)
		PRK13930	32..442	CDD:237564	158/413 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	315..352		2/36 (6%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D288077at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820