Protein Alignment Hsp70Bbb and hspa4l

DIOPT Version :10

• Sequence 1: NP_788663.1
• Gene: Hsp70Bbb / 50022
• FlyBaseID: FBgn0051354
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_690505.2
• Gene: hspa4l / 562019
• ZFINID: ZDB-GENE-030131-2412
• Length: 826
• Species: Danio rerio
• Alignment Length: 720
• Identity: 202/720 - (28%)
• Similarity: 354/720 - (49%)
• Gaps: 127/720 - (17%)

  Fly     1 MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVF 65
            |..:|||:|.....:.|.:.|.:|.|||:..:|.||:.::.....|.||:.||:|:..|.:|||.
Zfish     1 MSVVGIDVGFQNCYIAVARSGGIETIANEYSDRCTPACISLASKNRTIGNAAKSQIITNFKNTVH 65

  Fly    66 DAKRLIGRKYDDPKIAEDMKHWPFKVVS-DGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAE 129
            ..|:..||.:|||.:..:....|:.:.. |.|...|.|.|..|.|.|..|::::|:|||:|||:|
Zfish    66 GFKKFHGRAFDDPFVQGEKSRLPYSLHKLDNGNAGIKVRYLNEDKVFTIEQVTAMLLTKLKETSE 130

  Fly   130 AYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDK----NLKDE- 189
            ..|.:.:.|.||:||::|.|.:|::..||..|||||.||:||:.||.|||||:.|    |.:::
Zfish   131 HALKKPVVDCVISVPSFFTDVERRSVMDATQIAGLNCLRLINDTTAVALAYGIYKQDLPNPEEKP 195

  Fly   190 RNVLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSN 254
            |||:..|:|..::.|:|.:.::|.| ::.:||.|.:|||.:||..||.:..|:||.::|.:::.|
Zfish   196 RNVVFVDIGHSSYQVAIASFNKGKL-KMLATAFDPYLGGRNFDEILVEYFCEDFKNRFKLNVKDN 259

  Fly   255 PRALRRLRTAAERAKRTLS-SSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKA 318
            ||||.||....|:.|:.:| :|::..:.|:......|.:.|::|.:|||:|:.|......|:...
Zfish   260 PRALLRLYQECEKLKKLMSANSSDLPLNIECFMNDIDVHGKLNRTQFEEMCSQLMMRVEAPLRSV 324

  Fly   319 LNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQS 383
            :..:|:.:.:|:.|.:|||:||:|.::..:.:|| ||:.:.::|.|||||.|:|:|.||||  .:
Zfish   325 MEQSKLSRDEIYAIEVVGGATRMPAIKERISKFF-GKDTSTTLNADEAVARGSALQCAILS--PA 386

  Fly   384 GKIQDVLLVDVAPLSLGI-------ETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVY 441
            .|:::..:.|..|..:.:       |:.|         .|.:          ||.|.|....::.
Zfish   387 FKVREFSITDTVPFPITLRWKSPTDESVG---------ECEV----------YSKNHPAPFSKII 432

  Fly   442 EGERAMTKDNNA--------------LGTFDLSGIPPAPRG-VPQIEVTFDLDANGILNVSAK-- 489
            ...:....|..|              :|.|.:..:.|.|.| ..:::|...::.:||.:||:.
Zfish   433 TFHKKEPFDLEAFYSCPHDLPYPDVRIGRFSVQNVVPQPDGDSSKVKVKVRVNVHGIFSVSSASL 497

  Fly   490 -EMSTGKAKNI------TIKN--------------------------------------DKGRLS 509
             |...|:.:::      |::|                                      |:|..|
Zfish   498 IEKQKGEPEDVQMDTEPTVQNEGRPEEQSKMQVDQEGQGEQPSEEERANNSGIKDGDKQDQGASS 562

  Fly   510 Q------------------AEIDR-----MVNEAEKYADEDEKHRQRITSRNALESYVFNVKQSV 551
            .                  .::||     .|...:|...:|:..::|..::|.:|.||::::..:
Zfish   563 SKAKSKVKSVDLPILANTTRQLDRDVLTHFVEYEKKMIIQDKLEKERNDAKNGVEEYVYDLRDKL 627

  Fly   552 EQAPAGKLDEADKNSVLDKCNETIRWL-DSNTTAEKEEFDHKMEELTRHCSPIMTKMHQQGAGAA 615
            .......:.|.:.|.:.....:|..|| :.....:||.:.||:.||.::..||..:..:.    .
Zfish   628 CGIYEKYVTEDESNRLTIMLEDTENWLYEEGEDQDKEIYQHKLAELKKYGEPIEERYREH----E 688

  Fly   616 GGPGA 620
            |.|.|
Zfish   689 GRPRA 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bbb	NP_788663.1	PTZ00009	2..641	CDD:240227	201/719 (28%)
hspa4l	XP_690505.2	ASKHA_ATPase-like	2..384	CDD:483947	144/383 (38%)