Protein Alignment Hsp70Bbb and hspa12a.2

DIOPT Version :9

• Sequence 1: NP_788663.1
• Gene: Hsp70Bbb / 50022
• FlyBaseID: FBgn0051354
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_003198604.1
• Gene: hspa12a.2 / 559237
• ZFINID: ZDB-GENE-061009-20
• Length: 571
• Species: Danio rerio
• Alignment Length: 601
• Identity: 127/601 - (21%)
• Similarity: 235/601 - (39%)
• Gaps: 141/601 - (23%)

  Fly     4 IGIDLGTTYSCVGV----YQHGKVEIIAN---DQGNRT--TPSYVAFTDSE--RLIGDPA----- 52
            |.||.||:||...:    .|..:..:|.|   |.|..|  ||:.:.|.:.|  :..|..|
Zfish     8 IAIDFGTSYSGYAISFKTKQPQESILIPNWGVDYGYNTFKTPTCILFDEHETFQKFGYDAMMTYT 72

  Fly    53 KNQVAMNPRNT-VFDAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEI 116
            ::.|....|.: :|:..::   :..|.:|..|:    .....:||:.| .:....||.|:    :
Zfish    73 RSTVKSQARKSFLFEHFKM---ELYDKEIHRDL----MITAKNGGQMK-ALTVFSESLRY----L 125

  Fly   117 SSMVLTKMKE--TAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNV------LRIINEP 173
            ....|.|:||  |.:.::...:| .|:||||.:|.:.:|..::|...|||.:      |....||
Zfish   126 KDHALEKVKENPTGKTFIASDVT-WVLTVPAIWNAAAKQFMREAAIEAGLVIESEPERLVFALEP 189

  Fly   174 TAAAL--------AYGLDKNLKDE------RNVLIFDLGGGTFDVSI-LTIDEGSLFEVRSTAGD 223
            .||::        .|..::..:|.      ...::.|.||||.|::: ..:::|.|.|:.:.:|:
Zfish   190 EAASIYCKHLPSEGYISEEACRDTLEQKPGTQYMVVDCGGGTIDITVHEVVEDGKLKELNAASGN 254

  Fly   224 THLGGEDFDNRLVTHLAEEFKRK-YKKDLRSNPRALRRLRTAAERAKR-----------TLSSST 276
             .:||:..|.:.::.|.|.|..| |.|..:..|....:|:.....||.           ||....
Zfish   255 -DMGGQTVDRKFISFLKEIFSEKIYNKFEQDFPAEALKLKYDIALAKSCDQLVLIQCPVTLQELA 318

  Fly   277 EATIEIDALFEGQDFYTKVSRARFEE------------LCADLFRNTLQPVEKALNDAKMDKGQI 329
            :....|::.|||      |..|.::|            ...:..:.|.:.:||..::.:::   |
Zfish   319 KKEKAIESYFEG------VEGAEWDEGSIIIKEDKLQSFFDESLKTTAEKLEKITSNPELN---I 374

  Fly   330 HDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPD---------------------EAVAYGAAV 373
            ..::||||......::..|:|.|....:...:.|.                     .|:.||..:
Zfish   375 EYMLLVGGFAECKILKKFLKERFDKCKIVCPVEPQVVIIKGAIRYAKQPKVVKSRMSALTYGIRI 439

  Fly   374 QA---AILSGDQSGKI--QDVLLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKT--FSTYSD 431
            .|   .:|..|:|..:  :.....||.     .||       .:.:...:.|.:.:.  |:....
Zfish   440 DAPFDKVLHKDKSNYVNSEGQTYCDVC-----FET-------FVRKGESVNCDEVRQFFFNPSHT 492

  Fly   432 NQPGVSIQVYEGERAMTK--DN---NALGTFDLSGIPPAPRGVP---QIEVTFDLDANGILNVSA 488
            ||.....|.:.......:  |.   ..:|.|:: |:|....|:.   ::|:.|     |...:.|
Zfish   493 NQTSAIFQFFSTNEKQVQFIDEPGVEPVGFFEV-GMPKTDGGLSREIKLEIKF-----GSTEMKA 551

  Fly   489 KEMSTGKAKNITIKND 504
            ........:..::|:|
Zfish   552 TATDVDSGETTSVKHD 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bbb	NP_788663.1	PTZ00009	2..641	CDD:240227	127/601 (21%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	103/462 (22%)
hspa12a.2	XP_003198604.1	HSPA12_like_NBD	6..420	CDD:212671	99/434 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900