Protein Alignment Hsp70Bbb and hspa12a.3

DIOPT Version :10

• Sequence 1: NP_788663.1
• Gene: Hsp70Bbb / 50022
• FlyBaseID: FBgn0051354
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001038346.3
• Gene: hspa12a.3 / 559031
• ZFINID: ZDB-GENE-030131-8896
• Length: 571
• Species: Danio rerio
• Alignment Length: 608
• Identity: 123/608 - (20%)
• Similarity: 232/608 - (38%)
• Gaps: 159/608 - (26%)

  Fly     4 IGIDLGTTYSCVGV----YQHGKVEIIAN---DQGNRT--TPSYVAFTDSE--RLIG-DPAKNQV 56
            |.||.||:||...:    .|..:...|.|   :.|..|  ||:.:.|.:.|  :..| |......
Zfish     8 IAIDFGTSYSGYAISFKTKQPQESIQIPNWGVNFGYNTFKTPTCILFDEHETFQKFGYDAMMTYT 72

  Fly    57 AMNPRNT-----VFDAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEI 116
            ...|::.     :|:..::   :..|.:|..|:    .....:||:.| .:....||.|:    :
Zfish    73 RSTPKSQARKSFLFEHFKM---ELYDKEIHRDL----MITAKNGGQMK-ALTVFSESLRY----L 125

  Fly   117 SSMVLTKMKE--TAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNV------LRIINEP 173
            ....|.|:||  |.:.::...:| .|:||||.:|.:.:|..::|...|||.:      |....||
Zfish   126 KDHALEKIKENTTGKTFIASDVT-WVLTVPAIWNAAAKQFMREAAIEAGLVIESEPERLVFALEP 189

  Fly   174 TAAAL--------AYGLDKNLKDE------RNVLIFDLGGGTFDVSI-LTIDEGSLFEVRSTAGD 223
            .||::        .|..::..:|.      ...::.|.||||.|::: ..:::|.|.|:.:.:|:
Zfish   190 EAASIYCKQLPSEGYISEEACRDTLEQKPGTQYMVVDCGGGTIDITVHEVVEDGKLKELNAASGN 254

  Fly   224 THLGGEDFDNRLVTHLAEEFKRK-YKKDLRSNPRALRRLRTAAERAKR-----------TLSSST 276
             .:||:..|.:.::.|.|.|..| |.|..:..|....:|:.....||.           ||....
Zfish   255 -DMGGQTVDRKFISFLKEIFSEKIYNKFEQDFPAEALKLKYDIALAKSCDQLVLIQCPVTLQDLA 318

  Fly   277 EATIEIDALFEGQDFYTKVSRARFEE------------LCADLFRNTLQPVEKALNDAKMDKGQI 329
            :....|::.|||      |..|.::|            ...:..:.|.:.:||.:::.:::   |
Zfish   319 KKEKAIESYFEG------VEGAEWDEGSIIIKEDKLQSFFDESLKTTAEKLEKIMSNPELN---I 374

  Fly   330 HDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPD---------------------EAVAYGAAV 373
            ..::||||......::..|:|.|....:...:.|.                     .|:.||..:
Zfish   375 EYMLLVGGFAECKILKKFLKERFDKCKIVCPVEPQVVIIKGAIRYAKQPKVVKSRMSALTYGIRI 439

  Fly   374 QAAILSGDQSGKIQDVLLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTK-------------- 424
            .|........||...|.........:..||       .:.:...:.|.:.:
Zfish   440 DAPFDKVLHKGKTSYVNSEGQTYCDVCFET-------FVRKGESVNCDEVRQFFFNPSDTNQTFA 497

  Fly   425 TFSTYSDN--------QPGVSIQVYEGERAMTKDNNALGTFDLSGIPPAPRGVP---QIEVTFDL 478
            ||..:|.|        :|||               .::|.|.: |:|....|:.   ::|:.|
Zfish   498 TFQFFSTNEKQVQFIDEPGV---------------ESVGVFQV-GMPKTDGGLSREIKLEIKF-- 544

  Fly   479 DANGILNVSAKEMSTGKAKNITI 501
             .:..:..:|.::.:|:..::.:
Zfish   545 -GSTEMKATATDVDSGETTSVKL 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bbb	NP_788663.1	PTZ00009	2..641	CDD:240227	123/608 (20%)
hspa12a.3	NP_001038346.3	ASKHA_NBD_HSP70_HSPA12	8..420	CDD:466827	97/434 (22%)