Protein Alignment Hsp70Bbb and hsph1

DIOPT Version :9

• Sequence 1: NP_788663.1
• Gene: Hsp70Bbb / 50022
• FlyBaseID: FBgn0051354
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_001919957.2
• Gene: hsph1 / 557824
• ZFINID: ZDB-GENE-120410-4
• Length: 901
• Species: Danio rerio
• Alignment Length: 712
• Identity: 203/712 - (28%)
• Similarity: 350/712 - (49%)
• Gaps: 116/712 - (16%)

  Fly     1 MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVF 65
            |..:|.|:|....|:.|.:.|.:|.::|:..:|.|||.::|....|.||:.||||:..||.:|||
Zfish    63 MAVVGFDVGFQNCCIAVVKSGGIETVSNEFTDRCTPSVISFGSKNRAIGNAAKNQMITNPSSTVF 127

  Fly    66 DAKRLIGRKYDDPKIAEDMKHWPFKVV--SDGGKPKIGVE--YKGESKRFAPEEISSMVLTKMKE 126
            ..|||..|.|.|..:..:..:.|:.:|  :||   |:||:  |..:...|:.|:||:|:|||:|:
Zfish   128 HFKRLHSRLYHDKVVQAEKANLPYDLVPLNDG---KVGVQVMYLDQEHHFSIEQISAMLLTKLKD 189

  Fly   127 TAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGL--------D 183
            .|||.|.:.:.:.||::|::|.||:|::..||..|||||.|:::|:.||.||.||:        |
Zfish   190 IAEANLQKKVLECVISIPSFFTDSERRSVLDAAKIAGLNCLKLMNDSTAVALNYGIYKEDLPGSD 254

  Fly   184 KNLKDERNVLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYK 248
            :|.|   .|...|||...|.|||...:.|.: :|.|||.|.:|||:|||.|||.|...|||.||.
Zfish   255 ENPK---IVAFVDLGHSAFQVSICAFNRGKV-KVLSTAFDPYLGGKDFDQRLVDHFCAEFKSKYM 315

  Fly   249 KDLRSNPRALRRLRTAAERAKRTLSS-STEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTL 312
            .|::|..|||.||....|:.|:.:|| |||.::.|:...:.:|...:::||:|||:||||.....
Zfish   316 MDVKSKTRALLRLTQECEKLKKLMSSNSTELSLNIECFIDDKDVCGRMNRAKFEEMCADLIERVK 380

  Fly   313 QPVEKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAI 377
            ..:.||:..|.:....|..:.:|||:||||.|::.:..||. ::::.::|.|||||.|.|:|.|:
Zfish   381 FTLMKAVEQAGVRLQDISAVEIVGGATRIPAVKAQISSFFR-RDVSTTLNADEAVARGCALQCAM 444

  Fly   378 LSGDQSGKIQDVLLVDVAPLSLGIETA-----GGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVS 437
            ||  .:.::::..:.||.|..:.:..:     |....::..||  .||...|..:.|. |:|.:.
Zfish   445 LS--PAFRVREFSITDVIPFPISLSWSSEADEGKSCHEIFSRN--HPCPSAKMITFYR-NKPFIL 504

  Fly   438 IQVYEGERAMTKDNNALGTFDLSGIPPAP-RGVPQIEVTFDLDANGILNVSAK------------ 489
            ...|..:.::......:|.:.:..|.|.. |...:::|..:::.:|:::||:.
Zfish   505 EAFYSDKSSLPFPEAKIGEYKVQNIQPQENREKAKVKVKVEVNRSGVVSVSSAAVVLRVRSDESE 569

  Fly   490 ----------------------------EMSTG-------------------------------- 494
                                        |:|..
Zfish   570 ITEINEDVDSHDASDDTDVQDKTEEVNIELSVNKENLPTAQCPPMEKEQNQRETLSMNGEVNSHP 634

  Fly   495 --------KAKNITIKNDKGRLSQAEIDRM---VNEAEKYADEDEKHRQRITSRNALESYVFNVK 548
                    |.|::.:..::....|...||:   ..:..|...:|.:.::|..::||:|..|:..:
Zfish   635 PHAKKAKMKVKHVVLPMEETFNQQLPKDRLSAYTEQENKMIQQDRQEKERNNAKNAVEENVYYFR 699

  Fly   549 QSVEQAPAGKLDEADKNSVLDKCNETIRWL-DSNTTAEKEEFDHKMEELTRHCSPIMTKMHQ 609
            ..:|.:....|:..:..:..:..|.|..|| |.....:|:.:.:::.|:.:...|:..:..:
Zfish   700 HKLEGSYQTFLNAQEHQAFSELLNGTENWLYDEGADQDKQTYINRLAEIHKLGLPVENRYRE 761

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bbb	NP_788663.1	PTZ00009	2..641	CDD:240227	202/711 (28%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	155/388 (40%)
hsph1	XP_001919957.2	HSPH1_NBD	64..446	CDD:212689	155/389 (40%)
		HSP70	65..761	CDD:278441	202/708 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810