Protein Alignment Hsp70Bbb and Hsc70-2

DIOPT Version :10

• Sequence 1: NP_788663.1
• Gene: Hsp70Bbb / 50022
• FlyBaseID: FBgn0051354
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Alignment Length: 641
• Identity: 476/641 - (74%)
• Similarity: 552/641 - (86%)
• Gaps: 12/641 - (1%)

  Fly     1 MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVF 65
            :||||||||||||||||:|:.||||||||||||||||||||.::|||||||||||||||.:||||
  Fly     4 IPAIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKNTVF 68

  Fly    66 DAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEA 130
            |||||||||:||.||.||:|.|||||:::.|||||.||:|||.||||||||||||||||:|.||.
  Fly    69 DAKRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEV 133

  Fly   131 YLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKDERNVLIF 195
            |||..:.|||:||||||||||||||||||.|||||||||||||||||||||||||||.|||||||
  Fly   134 YLGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIF 198

  Fly   196 DLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRR 260
            ||||||||||:|:|||||||||::|||||||||||||||||.|.|||||||:|.|::.|.|||||
  Fly   199 DLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARALRR 263

  Fly   261 LRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMD 325
            ||||.|||||||||||||::|||||.||.|||:|:||||||||..||||:|:||||:||:|||||
  Fly   264 LRTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDAKMD 328

  Fly   326 KGQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVL 390
            |..|||:|||||||||||:|.|||:.|.||.||||||||||||||||||||||:|..|.:|||:|
  Fly   329 KKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQDLL 393

  Fly   391 LVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALG 455
            |||||||||||||||||||.|:|||.||||||.:.|:||||||..|:|||||||||||||||.||
  Fly   394 LVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNNLLG 458

  Fly   456 TFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEA 520
            ||:|:||||||||||||||.|||:|:|||||:||:.||||::.|||.|||||||:||||||::||
  Fly   459 TFNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRMLSEA 523

  Fly   521 EKYADEDEKHRQRITSRNALESYVFNVKQSVEQAPAGKLDEADKNSVLDKCNETIRWLDSNTTAE 585
            |||..||::.|:|:.|:|.||:|::..:|:|:.||:|.|.|.:::.|.|||:....|||.|:.||
  Fly   524 EKYKVEDDRQRERVQSKNNLEAYIYACRQAVDDAPSGVLSETERSKVRDKCSSEASWLDKNSLAE 588

  Fly   586 KEEFDHKMEELTRHCSPIMTKMHQQGAGAAGGPGANCGQQAGGFGGYSGPTVEEVD 641
            ||||:..::|..|.|:|||:|:|          |...|:.:.|.|  |.|||||||
  Fly   589 KEEFESHLKECQRICTPIMSKIH----------GGKKGKSSMGKG--SHPTVEEVD 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bbb	NP_788663.1	PTZ00009	2..641	CDD:240227	474/638 (74%)
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	474/639 (74%)