Protein Alignment Hsp70Bbb and T24H7.2

DIOPT Version :10

• Sequence 1: NP_788663.1
• Gene: Hsp70Bbb / 50022
• FlyBaseID: FBgn0051354
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_495249.1
• Gene: T24H7.2 / 174033
• WormBaseID: WBGene00020781
• Length: 925
• Species: Caenorhabditis elegans
• Alignment Length: 743
• Identity: 184/743 - (24%)
• Similarity: 303/743 - (40%)
• Gaps: 154/743 - (20%)

  Fly     1 MPAIGIDLGTTYSCVGVYQHG-KVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTV 64
            :.|:.|||||.:..:|:.:.| .::|..|.:..|.||:.|...|..|...|.|.......|....
 Worm    24 LAAMTIDLGTQFLKIGIVKPGIPMDIALNTESRRKTPNVVMIQDGHRTFADAAIGMQVRYPHLVH 88

  Fly    65 FDAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAE 129
            .....|:|:....|......:...|..|.|..|....:.:|...:.:..|.:::|:|...|:..|
 Worm    89 GQLNDLVGKSTQHPSFELFKRRNTFFEVDDAPKNASSINFKLGGESYTVEALTAMILANAKKFTE 153

  Fly   130 AYL-GESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGL--DKNLKDE-R 190
            .|. ...|.|.|||||.||..::|.|.:.|..:|||.||::||:.|||||::|:  .|.:.:: :
 Worm   154 EYAQAAEIKDVVITVPVYFTPAERLAVERAAQMAGLTVLQLINDGTAAALSHGIFRRKEIGEKPQ 218

  Fly   191 NVLIFDLGGGTFDVSILTI-------DEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKY- 247
            .::::|:|......:|:..       ::.....|.....|..|||.:..|||..||.|.|::.|
 Worm   219 RLMVYDMGAAKTTATIVEFKLVKEKYEKQPKMTVLGVGFDRTLGGIEMTNRLRDHLIEMFEKNYK 283

  Fly   248 -KKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNT 311
             |..:.:|.||:.:....|||.|:.||::.|...:|::..|..|...||:|..|..|.:|:....
 Worm   284 PKTKVNTNRRAMTKFSKEAERLKQVLSANAEHFAQIESAHEDIDAKLKVTREDFNHLISDMESRF 348

  Fly   312 LQPVEKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAA 376
            .:|:|:||..|::....|...||:|..||:||||.::|:....|.:...:|.|||||.||..|||
 Worm   349 GEPIEQALRMAQIPIDDIDQFVLMGAGTRVPKVQEIVQKTIGTKEIGKFLNTDEAVAMGALFQAA 413

  Fly   377 ILSGDQSGKIQDVLLVDVAPLSLGI----------ETAG--GVMTKLIERNCRIPC-KQTKTFST 428
            .||.....|..::....:.|:.:..          |..|  .|:..|...|...|. .:|.:.::
 Worm   414 HLSKGFKVKPFNIEEKVIFPVEVHFVSKIRDEKTEEITGEKNVVKTLFAANSVYPTHPKTISLTS 478

  Fly   429 YSDNQPGVSIQVYEGE-RAMTK----------DNNALGTFDLSGIPPAPRG-------VPQIEVT 475
            |||:   .|:.:..|: .:.||          ||  |...::||:..|.:.       ...::|:
 Worm   479 YSDD---FSVALKYGKIESFTKQQVQEIGSLLDN--LVDVEISGLSEALKNRSSEESEFKGVKVS 538

  Fly   476 FDLDANGIL-------------------------------------------------------- 484
            |.:||:||:
 Worm   539 FIVDASGIVRVRRAEALFEPKSGLVGSIASTISGLFSSKTEEGEPTTDDSTPQSTEEKTEEKESV 603

  Fly   485 -------------------------NVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNE----- 519
                                     |.:.|..|:|.|..  :|..|..|......|:.|:
 Worm   604 KVEDSTPEPEPETPVNSTSEESPKTNETEKNASSGNATE--VKEKKKELPSIVRLRITNKYPSAF 666

  Fly   520 -AEKYADEDEKHR------------QRITSRNALESYVFNVKQSVEQAP-AGKLDEADKNSVLDK 570
             ..||..::||.|            :|....|.|||:.|...|.:|:.. ...:.:.:|..:.|.
 Worm   667 VPNKYDVQEEKRRMEAFAEKERLASERAAVENELESFNFECSQYLEETEFTDYMADEEKTKLEDS 731

  Fly   571 CNETIRWLDSNTTAE--KEEFDHKMEEL 596
            ......||:.:.|.:  .::|...:.||
 Worm   732 VKRIRAWLEDDVTKDTPTKDFTDNLLEL 759

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bbb	NP_788663.1	PTZ00009	2..641	CDD:240227	184/742 (25%)
T24H7.2	NP_495249.1	ASKHA_NBD_HSP70_HYOU1	25..413	CDD:466828	121/387 (31%)