Protein Alignment Hsp70Bbb and Grp170

DIOPT Version :10

• Sequence 1: NP_788663.1
• Gene: Hsp70Bbb / 50022
• FlyBaseID: FBgn0051354
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_321225.4
• Gene: Grp170 / 1281282
• VectorBaseID: AGAMI1_004700
• Length: 975
• Species: Anopheles gambiae
• Alignment Length: 782
• Identity: 195/782 - (24%)
• Similarity: 330/782 - (42%)
• Gaps: 192/782 - (24%)

  Fly     4 IGIDLGTTYSCVGVYQHG-KVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDA 67
            :.:|||:.:..|||...| .:||..|.:..|.||:.:||.:.:|:.|:.|:......|.|:....
Mosquito    35 MSVDLGSEWMKVGVVSPGVPMEIALNKESKRKTPTTIAFRNGDRVFGEDAQTLGVRFPSNSFGYL 99

  Fly    68 KRLIGRKYDDPKIAEDMKHWP-FKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAY 131
            ..|:|:..|:|.:....|.:| :.:|:|  ..:..|.::...:::..||:.:.:|...|..||..
Mosquito   100 TDLLGKTVDNPMVDLYRKRFPYYDIVAD--PVRRTVVFRSGEEQYMIEELIAQLLQVAKSYAEDS 162

  Fly   132 LGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKDERN----- 191
            .|:.||:.|:.||.::..::|.|...|..:|.|.||::||:.||.||.||:.:  :.|.|
Mosquito   163 TGQLITECVLIVPGFYGQAERTALVAAARLANLKVLQLINDYTAVALNYGIFR--RKEINETAQY 225

  Fly   192 VLIFDLGGGTFDVSIL---------TIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKR-- 245
            .|.:|:|......:::         |.:...:.:|.....|..|||.:...||..:|..||.:
Mosquito   226 FLFYDMGAYKTSAAVVSYQLVKDKATRETHPVVQVLGVGYDRTLGGLEMQVRLRDYLGREFNKMG 290

  Fly   246 KYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRN 310
            |.|.|:.:||||:.:|...|.|.|..||::||...:|:.|.:.|||...|.|.:|||||.||:..
Mosquito   291 KTKTDVFTNPRAMAKLFKEAGRLKNVLSANTEHYAQIEGLLDEQDFRLLVKREQFEELCKDLYER 355

  Fly   311 TLQPVEKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQA 375
            ...|::|||..:.:....|:.:||.||:||:||||.:|:... |:.|..::|.|||...||..:|
Mosquito   356 VTAPLDKALAVSGLALDVINQVVLFGGNTRVPKVQDILRTHI-GQELAKNLNADEAACMGAVYRA 419

  Fly   376 AILSGDQSG-KIQDVLLVDVA--PLSLGIETAG-GVMTKLIERNC-----RIPCKQTKTFSTYSD 431
            |.|:   :| |::..:..|..  |:.:..:..| ...|:.:.|..     ..|.|:..||:.::|
Mosquito   420 ADLA---TGFKVKKFITKDAVLFPIQVVFDREGESGATRQVRRTLFGSMNSYPQKKVITFNKHTD 481

  Fly   432 NQPGVSIQVYEGERAMTKDNNALGTFDLSGIPPA---------------PRGVPQIEVTFDLDAN 481
            :.. .::|..|.:..:..|...||:.||:.:..:               .:|   |:..|.||.:
Mosquito   482 DFE-FTVQYAELDAVLKGDTETLGSPDLARVQLSEVAKRLKASVAENVESKG---IKAHFLLDDS 542

  Fly   482 GILNVS--------------------------------------------------------AKE 490
            ||.:::                                                        .:|
Mosquito   543 GIFSLANVELVLEKTVTKEEEDEDESTFQKIGNTISKLFSGDSADKPAEEKPPTEGGAEAKDEEE 607

  Fly   491 MSTGK----------------------------------------------------AKNITIKN 503
            .::||                                                    |||.|:|.
Mosquito   608 PASGKEGKESAEEEQQQQQEEGKKQSAKDKEADGGAKDAKPEAGEPADKKAADEGTEAKNATVKP 672

  Fly   504 D--------------------KGRLSQAEIDRMVNEAEKYADEDEKHRQ-RITSRNALESYVFNV 547
            .                    .|.|..|...|:     ...||.:|.:| |.|:.|||||||.:.
Mosquito   673 KIVTLKEPIPSKVELAYVVPLDGELFDASAKRL-----SALDEVDKAKQRRETALNALESYVIDA 732

  Fly   548 KQSV-EQAPAGKLDEADKNSVLDKCNETIRWL-DSNTTAEKEEFDHKMEELTRHCSPIMTK--MH 608
            :..: ||..|....|.:..::..:|.|...|| :..:.|:.|.::.|:|||....:.:..:  .|
Mosquito   733 QVKLDEQEYASCATETEIETIRKRCGEISEWLYEDGSDADAETYETKLEELRGVANEVYARHWEH 797

  Fly   609 QQ 610
            |:
Mosquito   798 QE 799

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bbb	NP_788663.1	PTZ00009	2..641	CDD:240227	195/782 (25%)
Grp170	XP_321225.4	None