Protein Alignment Hsp70Bbb and hsp70.2

DIOPT Version :10

• Sequence 1: NP_788663.1
• Gene: Hsp70Bbb / 50022
• FlyBaseID: FBgn0051354
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001349289.1
• Gene: hsp70.2 / 100535101
• ZFINID: ZDB-GENE-110405-1
• Length: 643
• Species: Danio rerio
• Alignment Length: 642
• Identity: 479/642 - (74%)
• Similarity: 552/642 - (85%)
• Gaps: 9/642 - (1%)

  Fly     3 AIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDA 67
            |||||||||||||||:|||||||||||||||||||||||||:||||||.|||||||||.||||||
Zfish     8 AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTVFDA 72

  Fly    68 KRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYL 132
            ||||||::|||.:..|||||.|||||||||||:.||:|||:|.|.|||||||||.||||.|||||
Zfish    73 KRLIGRRFDDPVVQSDMKHWSFKVVSDGGKPKVAVEHKGENKTFNPEEISSMVLVKMKEIAEAYL 137

  Fly   133 GESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKDERNVLIFDL 197
            |:.:|:|||||||||||||||||||||.|||||||||||||||||:||||||....|||||||||
Zfish   138 GQKVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGKSSERNVLIFDL 202

  Fly   198 GGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRLR 262
            ||||||||||||::| :|||::|||||||||||||||:|.|..||||||:|||:..|.|||||||
Zfish   203 GGGTFDVSILTIEDG-IFEVKATAGDTHLGGEDFDNRMVNHFVEEFKRKHKKDISQNKRALRRLR 266

  Fly   263 TAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKG 327
            ||.||||||||||::|:||||:|:||.||||.::||||||||:||||.||.||||||.||||||.
Zfish   267 TACERAKRTLSSSSQASIEIDSLYEGIDFYTSITRARFEELCSDLFRGTLDPVEKALRDAKMDKA 331

  Fly   328 QIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLV 392
            ||||||||||||||||:|.|||:||:|:.||.|||||||||||||||||||.||.||.:||:||:
Zfish   332 QIHDIVLVGGSTRIPKIQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILMGDTSGNVQDLLLL 396

  Fly   393 DVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALGTF 457
            |||||||||||||||||.||:||..||.|||:||||||||||||.|||:|||||||||||.||.|
Zfish   397 DVAPLSLGIETAGGVMTALIKRNTTIPTKQTQTFSTYSDNQPGVLIQVFEGERAMTKDNNLLGKF 461

  Fly   458 DLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEK 522
            :|:|||||||||||||||||:||||||||||.:.||||...|||.|||||||:.||:|||.||:.
Zfish   462 ELTGIPPAPRGVPQIEVTFDIDANGILNVSAADKSTGKQNKITITNDKGRLSKEEIERMVQEADN 526

  Fly   523 YADEDEKHRQRITSRNALESYVFNVKQSVEQAP-AGKLDEADKNSVLDKCNETIRWLDSNTTAEK 586
            |..||:..|::|:::|:||||.||:|.|||... .||:.|.||..|::||||.:.||::|..|:|
Zfish   527 YKAEDDLQREKISAKNSLESYAFNMKNSVEDDNLKGKISEEDKKRVIEKCNEAVSWLENNQLADK 591

  Fly   587 EEFDHKMEELTRHCSPIMTKMHQQGAGAAGGPGANCGQQAGGFGGYS--GPTVEEVD 641
            ||::|:::||.:.|:|:::|::|.|..|.|     ||.||.|..|.|  |||:||||
Zfish   592 EEYEHQLKELEKVCNPVISKLYQGGMPAGG-----CGAQARGASGASAQGPTIEEVD 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Bbb	NP_788663.1	PTZ00009	2..641	CDD:240227	477/640 (75%)
hsp70.2	NP_001349289.1	PTZ00009	5..643	CDD:240227	477/640 (75%)