Protein Alignment CG45263 and Kirrel3

DIOPT Version :10

• Sequence 1: NP_731246.2
• Gene: CG45263 / 50003
• FlyBaseID: FBgn0266801
• Length: 1876
• Species: Drosophila melanogaster
• Sequence 2: NP_001420714.1
• Gene: Kirrel3 / 67703
• MGIID: 1914953
• Length: 803
• Species: Mus musculus
• Alignment Length: 861
• Identity: 206/861 - (23%)
• Similarity: 325/861 - (37%)
• Gaps: 192/861 - (22%)

  Fly    54 FSEQPKYTEVNPAEDTLLTCKVIDKRGTCSWQKDNKPVGIYTKKYEWASRMPTSDNGNVLHLDLH 118
            ||:||:...|...:...|.|.:.:..|...|.||...:|:......:...:..   ||
Mouse    50 FSQQPQDQVVVSGQPVTLLCAIPEYDGFVLWIKDGLALGVGRDLSSYPQYLVV---GN------- 104

  Fly   119 PPPVQLGGDCSLWIRSATLDFDDGLWECQVTASDFTTQDALTSQPVRLVVRVAPQRPRLEYEAVH 183
                .|.|:..|.|..|.|. ||.::|||      ..|.|:.|:|.||.|.|.|..|       .
Mouse   105 ----HLSGEHHLKILRAELQ-DDAVYECQ------AIQAAIRSRPARLTVLVPPDDP-------I 151

  Fly   184 VPPGHNITADAGALATVKCISHYGNPPATLKWFLGDQEISPIHPQMNATEPDNPRTWSAT----- 243
            :..|..|:..||....:.|.:....|.|::.|             :...|..|..|:|.|
Mouse   152 ILGGPVISLRAGDPLNLTCHADNAKPAASIIW-------------LRKGEVINGATYSKTLLRDG 203

  Fly   244 ------SVVQVSAMRERHGDILRCAAYHESYTAKSV----VVEARLDVKYAPSIRLIGSPEIDLE 298
                  |.:.:|.....:|..:.|.|     |.|::    .....:|:::.|.:.|...|:..||
Mouse   204 KRESIVSTLFISPGDVENGQSIVCRA-----TNKAIPGGKETSVTIDIQHPPLVNLSVEPQPVLE 263

  Fly   299 EDKDALVLRCVADANPPASIVWRRAGRSEI----------ASLQETLQLRPVGRRDAGLYTCQAQ 353
            :  :.:...|.|.|| ||...:|.|.|..|          .::..|....||        :|:..
Mouse   264 D--NIVTFHCSAKAN-PAVTQYRWAKRGHIIKEASGELYRTTVDYTYFSEPV--------SCEVT 317

  Fly   354 NSVGTSEQLSVQLDVKYPPKIISAGPDRLTTAPLFSPAAFECLADGNPLPSFKWVQRMAHGSKYV 418
            |::| |..||..:||.:.|::.|. |..| ...|.|.|.|.|...|||..:..|::|   ||..|
Mouse   318 NALG-STNLSRTVDVYFGPRMTSE-PQSL-LVDLGSDAVFSCAWIGNPSLTIVWMKR---GSGVV 376

  Fly   419 ERGSESRLVIDNVTYEYQGEYECRA-TSYINGQERVAISDPVSLQVVGAPQVLRLHPSLHTVSVK 482
             ..:|..|.:.:|..|..|:|.||| ...:...||     .|:|.|.|.|.:    .|..|....
Mouse   377 -LSNEKTLTLKSVRQEDAGKYVCRAVVPRVGAGER-----EVTLTVNGPPII----SSTQTQHAL 431

  Fly   483 RGEAASLTMVVCADPRPQRVAWEWGSLRLEAGSGIDRFRADDMQPDTREDCYLSTLHILHADEHD 547
            .||...:...:.:.|.|.|:||.|....||:|:. .|:..:.:   ..|:..:|||.|.:....|
Mouse   432 HGEKGQIKCFIRSTPPPDRIAWSWKENVLESGTS-GRYTVETV---NTEEGVISTLTISNIVRAD 492

  Fly   548 SRPYY-LVVENERGTDRHAIHLIVEGT--------FAEPYEMSYLMGVAGGCMAAILLLVCLCIY 603
            .:..| ....|..|:|...|.|..:|:        .||...|:.::|||.|...|.|:|:...:
Mouse   493 FQTIYNCTAWNSFGSDTEIIRLKEQGSEMKSGAGLEAESVPMAVIIGVAVGAGVAFLVLMATIV- 556

  Fly   604 AIKSKRCCFKG--STGYKS--SDKDSEK---------ADLKS-------------RSDSTSGPQG 642
                ..||.:.  |||.:.  |.:.:||         |:||.             ..:.:||.:.
Mouse   557 ----AFCCARSQRSTGGRPGISGRGTEKKARLRLPRRANLKGVVSAKNDIRVEIVHKEPSSGREA 617

  Fly   643 DSIYTTPAGFHHHQQQQQQQQQQQHAAAAAAAALHAASQHPQQQYPGHGSPEAMKVRMAAMILQP 707
            :. :||     ..|....:.:.||.:.......|....:..|.                   |:.
Mouse   618 ED-HTT-----IKQLMMDRGEFQQDSVLKQLEVLKEEEKEFQN-------------------LKD 657

  Fly   708 PTRVXQAIDTTSE--SNEQLTQQQQQDDNKNKNKNENEHQNELTDQHTT-SNEQRLDD------- 762
            ||....:::|..|  |...::....|.|.:...|.........|:.::| |.:.||.|
Mouse   658 PTNGYYSVNTFKEHHSTPTISLSSCQPDLRPTGKQRVPTGMSFTNIYSTLSGQGRLYDYGQRFVL 722

  Fly   763 ----SSVS--HNNNNNHKISSTSTTVLTNSDNNNTS--------EVAKASDSSNSEGGSSLTSSK 813
                ||:.  ........:|.:|:.:.|..|::.:|        :..|||.:|.|....|.:||:
Mouse   723 GMGSSSIELCEREFQRGSLSDSSSFLDTQCDSSVSSSGKQDGYVQFDKASKASASSSHHSQSSSQ 787

  Fly   814 TSSSKRDLENNMNRDI 829
            .|...|.|:..|...:
Mouse   788 NSDPSRPLQRRMQTHV 803

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45263	NP_731246.2	Ig	170..281	CDD:472250	23/125 (18%)
		Ig strand B	198..202	CDD:409353	0/3 (0%)
		Ig strand C	212..216	CDD:409353	0/3 (0%)
		Ig strand E	244..248	CDD:409353	1/3 (33%)
		Ig strand F	258..263	CDD:409353	1/4 (25%)
		Ig strand G	274..277	CDD:409353	0/2 (0%)
		Ig	304..364	CDD:409353	18/69 (26%)
		Ig strand B	304..308	CDD:409353	0/3 (0%)
		Ig strand C	317..321	CDD:409353	0/3 (0%)
		Ig strand E	334..337	CDD:409353	1/2 (50%)
		Ig strand F	347..352	CDD:409353	1/4 (25%)
		Ig strand G	361..364	CDD:409353	1/2 (50%)
		Ig_3	371..444	CDD:464046	26/73 (36%)
		Ig	475..568	CDD:472250	25/93 (27%)
		Ig strand B	487..491	CDD:409353	0/3 (0%)
		Ig strand C	501..505	CDD:409353	2/3 (67%)
		Ig strand E	536..540	CDD:409353	3/3 (100%)
		Ig strand F	550..555	CDD:409353	1/5 (20%)
		Ig strand G	563..566	CDD:409353	0/2 (0%)
Kirrel3	NP_001420714.1	IG_like	54..143	CDD:214653	28/109 (26%)
		Ig strand B	65..69	CDD:409390	1/3 (33%)
		Ig strand C	73..81	CDD:409390	1/7 (14%)
		Ig strand E	110..114	CDD:409390	1/3 (33%)
		Ig strand F	124..129	CDD:409390	3/10 (30%)
		Ig strand G	135..139	CDD:409390	1/3 (33%)
		IgI_2_KIRREL3-like	149..246	CDD:409416	21/121 (17%)
		Ig strand A	150..153	CDD:409416	1/9 (11%)
		Ig strand A'	156..160	CDD:409416	1/3 (33%)
		Ig strand B	167..174	CDD:409416	1/6 (17%)
		Ig strand C	179..184	CDD:409416	2/17 (12%)
		Ig strand C'	187..189	CDD:409416	0/1 (0%)
		Ig strand D	192..199	CDD:409416	2/6 (33%)
		Ig strand E	206..214	CDD:409416	1/7 (14%)
		Ig strand F	223..231	CDD:409416	2/12 (17%)
		Ig strand G	237..243	CDD:409416	0/5 (0%)
		Ig	<267..334	CDD:472250	21/76 (28%)
		Ig strand B	267..271	CDD:409437	0/3 (0%)
		Ig strand C	280..285	CDD:409437	1/4 (25%)
		Ig strand E	304..308	CDD:409437	1/3 (33%)
		Ig strand G	326..329	CDD:409437	1/2 (50%)
		Ig	335..416	CDD:472250	30/91 (33%)
		Ig strand B	352..356	CDD:409549	2/3 (67%)
		Ig strand C	365..369	CDD:409549	0/3 (0%)
		Ig strand E	381..385	CDD:409549	1/3 (33%)
		IgI_5_KIRREL3	418..515	CDD:409479	27/104 (26%)
		Ig strand A	419..423	CDD:409479	1/7 (14%)
		Ig strand A'	425..428	CDD:409479	0/2 (0%)
		Ig strand B	436..443	CDD:409479	0/6 (0%)
		Ig strand C	450..455	CDD:409479	3/4 (75%)
		Ig strand C'	457..460	CDD:409479	0/2 (0%)
		Ig strand D	468..475	CDD:409479	0/9 (0%)
		Ig strand E	478..485	CDD:409479	3/6 (50%)
		Ig strand F	496..503	CDD:409479	1/6 (17%)
		Ig strand G	506..513	CDD:409479	2/6 (33%)