Protein Alignment CG45263 and Il1rapl2

DIOPT Version :9

• Sequence 1: NP_731246.2
• Gene: CG45263 / 50003
• FlyBaseID: FBgn0266801
• Length: 1876
• Species: Drosophila melanogaster
• Sequence 2: NP_109613.1
• Gene: Il1rapl2 / 60367
• MGIID: 1913106
• Length: 686
• Species: Mus musculus
• Alignment Length: 523
• Identity: 103/523 - (19%)
• Similarity: 168/523 - (32%)
• Gaps: 180/523 - (34%)

  Fly   141 DGLWECQVTASDFTTQDALTSQPVRLVVRVAPQRPRLEYEAVHVPPGHNITADAGALATVKCI-- 203
            ||   |...:.|..|..||..:|||                                  |||.
Mouse    29 DG---CIDWSVDLKTYMALAGEPVR----------------------------------VKCALF 56

  Fly   204 -----SHYGNPPAT---LKWF--LGDQEISPIHPQMNATEPDNPRTWSATSVVQVSAMRERHGDI 258
                 ::|....:|   |.|:  .||.|...|..::..::.:: ..|..::..|.|..   :..:
Mouse    57 YSYIRTNYSMAQSTGLRLMWYRNKGDLEEPIIFSEVRMSKEED-AIWFHSAEEQDSGF---YTCV 117

  Fly   259 LRCAAYHESYTAKSVVVEARLDVKYAPSIRLIGSPEI---------DLEEDKDALVLRCVADANP 314
            ||.:.|....:....|.|....:.|...||.:...|:         |:::.|.       :|..|
Mouse   118 LRNSTYCMKVSMSLTVAENESGLCYNSRIRYLEKSEVTKRKEISCPDMDDFKK-------SDQEP 175

  Fly   315 PASIVW-----RRAGRSEIASLQETLQLRPVGRRDAGLYTCQAQNSVGTSEQLSVQLDVKYPPKI 374
              .:||     .:..||.|......|.::.|...|.|.|||                ::||..|:
Mouse   176 --DVVWYKECKPKMWRSIIIQKGNALLIQEVQEEDGGNYTC----------------ELKYEGKL 222

  Fly   375 ISAGPDRLTTA--------PLF--------------SPAAFECLA----DGNPLPSFKWVQRMAH 413
            :....:...||        |||              .|....|.|    .|...|...|::
Mouse   223 VRRTTELKVTALLTDKPPKPLFPMENQPSVIDVQLGKPLNIPCKAFFGFSGESGPMIYWMK---- 283

  Fly   414 GSKYVE------RGSESR--------------LVIDNVTYEYQGEYECRATSYINGQERVAISDP 458
            |.|::|      |..|.|              |:.|:|.......|.|...:. ||::..::
Mouse   284 GEKFIEELAGHIREGEIRLLKEHLGEKEVELTLIFDSVVEADLANYTCHVENR-NGRKHASV--- 344

  Fly   459 VSLQVVGAPQVLRLHPSLHTVSVKRGEAASLTMVVCADPRPQRVAWEWGSLRLEAGSGIDRFRAD 523
                      :||....::.:.:..|..|...:::..     .|.::..::.|..... .||..|
Mouse   345 ----------LLRKKDLIYKIELAGGLGAIFLLLILL-----LVVYKCYNIELMLFYR-QRFGGD 393

  Fly   524 DMQPDTRE-DCYLSTLHI----LHADEHDSRPYYL-----VVENERG-----TDRHAIHLIVEGT 573
            :...|.:| |.|||...:    |..|..:...:.|     |:|...|     .:|   .||..||
Mouse   394 ETTDDNKEYDAYLSYTKVDQDTLDCDNTEEEQFALEILPDVLEKHYGYKLFIPER---DLIPSGT 455

  Fly   574 FAE 576
            :.|
Mouse   456 YIE 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45263	NP_731246.2	I-set	53..149	CDD:254352	3/7 (43%)
		Ig	198..281	CDD:299845	19/94 (20%)
		IG_like	302..368	CDD:214653	14/70 (20%)
		IGc2	302..357	CDD:197706	14/59 (24%)
		Ig	372..446	CDD:299845	23/119 (19%)
		Ig	475..568	CDD:299845	20/107 (19%)
		IG_like	478..570	CDD:214653	21/106 (20%)
Il1rapl2	NP_109613.1	Ig1_IL1RAPL-1_like	32..133	CDD:143304	24/138 (17%)
		Ig2_IL1R_like	146..237	CDD:319309	24/115 (21%)
		IG_like	250..347	CDD:214653	19/114 (17%)
		TIR	401..559	CDD:214587	17/61 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910