Protein Alignment CG45263 and si:dkey-33i11.1

DIOPT Version :10

• Sequence 1: NP_731246.2
• Gene: CG45263 / 50003
• FlyBaseID: FBgn0266801
• Length: 1876
• Species: Drosophila melanogaster
• Sequence 2: XP_009290914.1
• Gene: si:dkey-33i11.1 / 569162
• ZFINID: ZDB-GENE-030131-4630
• Length: 652
• Species: Danio rerio
• Alignment Length: 646
• Identity: 139/646 - (21%)
• Similarity: 234/646 - (36%)
• Gaps: 157/646 - (24%)

  Fly    97 KYEWASRMPT--------SDNGN---VLHLD--LHPPPVQ-----LGG--DCSLWIRSATLDFDD 141
            :|::.|...:        ||:|.   ..|.|  |..|..:     :||  .|||.|.:..|. |.
Zfish    46 RYDYPSPFSSTRVMWFHISDDGRREIAFHTDAGLLSPSYRDRIKYIGGYKRCSLQITNVKLS-DA 109

  Fly   142 GLWECQVTASD----FTTQDALTSQPVRLVVRVAPQRPRLEYEAVHVPPGHNITADAGALATVKC 202
            |::..:....:    :|:.||:|.....|.|.|.|  ||:          .|:.| ||....:.|
Zfish   110 GMYHFRFETDNQQGRWTSPDAITLSVTELQVNVHP--PRI----------GNMFA-AGETVFLSC 161

  Fly   203 ISHYGNPPATLKWFLGDQEISPIHPQMNATEPDNPRTWSATSVVQVSAMRERHGDILRCAAYHES 267
            ::.....|.  |.|              |...:......::.:..:.....:|..         :
Zfish   162 VARGCAAPG--KSF--------------ALYRNGVNLGQSSKLSAIYNFNSQHAG---------T 201

  Fly   268 YTAKSVVVE------ARLDVKYAPSIRLIGSPEIDLEEDKDALVLRCVADANPPA-SIVWRRAGR 325
            ||.:.:.::      ..|.:.|.|....|.....:...:.|::.|.|.:|..||| |..|.:.|.
Zfish   202 YTCRPLPIQNVQSPGLTLALGYPPRYTAIQISPREAVREGDSVTLTCSSDGAPPAESFAWFKEGE 266

  Fly   326 SEIASLQET----LQLRPVGRRDAGLYTCQAQNSVGTSEQLSVQLDVKYPPKIISAGPDRLTTAP 386
            |  .||.::    |:|..:..||.|.|.|.|:|.:||.....|.|::.||||         .|..
Zfish   267 S--GSLPDSFKPELRLWSLDYRDYGEYFCVARNPLGTDRSRPVLLNLTYPPK---------NTRI 320

  Fly   387 LFSPAA---------FECLADGNPLPSFKWVQRMAHGSKYVERGSESRLVIDNVTYEYQGEYECR 442
            |.||..         ..|.::.|| |..|:.....:|.:...:|:...|...:|...:.|:|.|.
Zfish   321 LISPKGDIMEGFSVNLTCSSNANP-PVLKYAWYKVNGGQPWTKGTAQNLTFFSVRSHHAGQYYCT 384

  Fly   443 ATSYINGQERVAISDPVSLQVVGAPQVLRLHPSLHTVSVKRGEAASLTMVVCADPRPQRVAWEWG 507
            |.:...    :..|..:||.|:.||:...:.....|| ::.|.:.:||.:..|:|..:...|.
Zfish   385 AWNAFG----MGTSPTISLPVLYAPKNTSVLAQPSTV-IEAGSSLTLTCISQANPAVENYTWH-- 442

  Fly   508 SLRLEAGSGIDRFRADDMQPDTREDCYLSTLHILHADEHDSRPYYLVVENERGTDRHAIHLI-VE 571
                       |....|.. :||..   .:..|.......|..||....|..|.....|..: |.
Zfish   443 -----------RINTADAW-ETRSG---PSYTIAEVSSGASGQYYCEARNRIGAHSSPILTVKVR 492

  Fly   572 GTFAEPYEMSYLMGVAGGCMA-AILLLVCLCIYAI------KSKRC-----------CFKGST-- 616
            |.. :...::..:||:.|.:: .:::::...::.:      :.|:|           .|..||
Zfish   493 GRL-KVIALASAVGVSIGLISLTVVVMISKNMHRVDTENLEEEKQCSPVVDLPVDHTSFSESTSQ 556

  Fly   617 -----GYKSSDKDSEKADLKSRSDSTSGP----------QGDSIYTTPAGFHHHQQQQQQQ 662
                 |.|.||...|..::...|..:..|          ||...|.|   .|:.:...:.|
Zfish   557 TFLLKGTKMSDIPEEPEEVYESSHPSIVPLKDAAPSSEEQGKINYIT---VHYSRMPSRDQ 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45263	NP_731246.2	Ig	170..281	CDD:472250	17/116 (15%)
		Ig strand B	198..202	CDD:409353	0/3 (0%)
		Ig strand C	212..216	CDD:409353	1/3 (33%)
		Ig strand E	244..248	CDD:409353	0/3 (0%)
		Ig strand F	258..263	CDD:409353	0/4 (0%)
		Ig strand G	274..277	CDD:409353	0/8 (0%)
		Ig	304..364	CDD:409353	23/64 (36%)
		Ig strand B	304..308	CDD:409353	1/3 (33%)
		Ig strand C	317..321	CDD:409353	1/3 (33%)
		Ig strand E	334..337	CDD:409353	1/6 (17%)
		Ig strand F	347..352	CDD:409353	2/4 (50%)
		Ig strand G	361..364	CDD:409353	0/2 (0%)
		Ig_3	371..444	CDD:464046	19/81 (23%)
		Ig	475..568	CDD:472250	19/92 (21%)
		Ig strand B	487..491	CDD:409353	1/3 (33%)
		Ig strand C	501..505	CDD:409353	0/3 (0%)
		Ig strand E	536..540	CDD:409353	0/3 (0%)
		Ig strand F	550..555	CDD:409353	2/4 (50%)
		Ig strand G	563..566	CDD:409353	0/2 (0%)
si:dkey-33i11.1	XP_009290914.1	Ig	32..136	CDD:472250	22/90 (24%)
		Ig strand B	41..45	CDD:409353
		Ig strand E	97..101	CDD:409353	3/3 (100%)
		Ig strand F	111..116	CDD:409353	0/4 (0%)
		Ig_2	154..>206	CDD:464026	9/76 (12%)
		Ig_2	233..310	CDD:464026	25/78 (32%)
		Ig_2	320..401	CDD:464026	19/85 (22%)
		Ig_2	409..491	CDD:464026	19/99 (19%)