DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG45263 and sns

DIOPT Version :9

Sequence 1:NP_731246.2 Gene:CG45263 / 50003 FlyBaseID:FBgn0266801 Length:1876 Species:Drosophila melanogaster
Sequence 2:NP_001036532.1 Gene:sns / 44097 FlyBaseID:FBgn0024189 Length:1542 Species:Drosophila melanogaster


Alignment Length:1133 Identity:226/1133 - (19%)
Similarity:379/1133 - (33%) Gaps:367/1133 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    81 TCSWQKDNKPVGIYTKKYEWASRMPTSDNGNVLHLDLHPPPVQLGGDCSLWIRSATLDFDDGLWE 145
            |.:|.|::|.:....:    |:....|....:|                     |.:..:...:.
  Fly   514 TLTWYKNDKRINSVIR----AADKSVSAEITIL---------------------ANVSDNQAQYR 553

  Fly   146 CQVTASDFTTQDALTSQPVRLVVRVAPQRPRLEYEAVHVPPGHNITADAGALATVKCISHYGNPP 210
            |:  ||:..|:..| .|...|.|..||:..::..|...:.||..        ||:.|.|...|||
  Fly   554 CE--ASNSATEIPL-FQSTTLSVHFAPETVKIRIEPEELRPGME--------ATIICDSSSSNPP 607

  Fly   211 ATLKWFLGDQEISPIHPQMNATEPDNPRTWSAT-SVVQ--VSAMRERHGDILRCAAYHESYTAKS 272
            |.|.|:   ::..||....|.::|.   .|..| |.::  |:..:|.:|.:..|.:.:|: ..:|
  Fly   608 AKLSWW---KDGIPIEGINNTSKPG---LWGGTVSTLEFRVNVTQEMNGQVYTCQSANEA-LQRS 665

  Fly   273 VVVEARLDVKYAPSIRLIGSPE---IDLEEDKDALVLRCVADANP-PASIVWRRAGRS------- 326
            ......|||.|.|  :.:..|.   :.:|  .::|.:.....||| |.:..|.:.|.:       
  Fly   666 AHEAVSLDVLYRP--KFVPPPSSTAVGVE--GESLQVSLQTRANPTPVTYKWTKDGTTIPQDGDH 726

  Fly   327 EIASLQETLQLRPVGRRDAGLYTCQAQNSVGTSEQLSVQLDVKYPPKIISAGPDRLTTAPLFSPA 391
            .|.:...:|....:.|.|||:|:|.|.||.| ...|::.:.|:|...|.|.. :.:...| ...|
  Fly   727 RIFADGGSLNFTRLHRDDAGIYSCSASNSQG-GATLNITVVVEYGTTIKSVS-ENIVVNP-GEDA 788

  Fly   392 AFECLADGNPLPS--FKWVQ-----------RMAHGSKYVERGSESRLVIDNVTYEYQGEYECRA 443
            ...|..:|.||..  .||.:           ..|:|:.|        |.|.:...|..|.:.|.|
  Fly   789 MLSCTVEGKPLTEEHVKWERVGYDMTVKTSTTFANGTSY--------LHIKDAKREDVGNFRCVA 845

  Fly   444 TSYINGQERVAISDPVSLQVVGAPQVLRLHPSLHTVSVKRGEAASLTMVVCADPRPQRVAW---- 504
            .:.::.    ..:..:.|.|..||::.:. |:|...:...||...|.......|:||.: |    
  Fly   846 DNRVDN----PTNRDILLIVKFAPEIAKT-PTLLRAASGTGERGRLPCRAQGSPKPQFI-WRQDK 904

  Fly   505 -----------------------------------EWGS----LRLEAGSGIDRFRAD-DMQPDT 529
                                               ::|:    .|.|.|..::..|.: ..|||.
  Fly   905 KDLPINRTYKYEVEERKIDSLTYESTLIVDKVAPADYGAYECVARNELGEAVETVRLEITSQPDP 969

  Fly   530 REDCYLSTLHILHADEHDS-----------------RPYYLVVENER----------------GT 561
            .     .:|:||:. .||:                 |..|.:.:.|:                |.
  Fly   970 P-----LSLNILNV-THDTVTLAWTPGFDGGLKASYRVRYRMADREQYKYIDGLPNSHKLTIGGL 1028

  Fly   562 DRHAIHLIVEGTFAEPYEMSYLMGVA-----------------------------GGCMAAIL-- 595
            ..:.::|....::.|..:.|||..:|                             ||....:|  
  Fly  1029 RMNTLYLFSVMSWNELGQSSYLPDLARAETKEAPPPSHPASSLGGGPPTTSQTPLGGTSGMLLVG 1093

  Fly   596 -----LLVCLCIYAIKSKRCCFKGSTGYKSSDKDSEK------ADLKSRSDSTSGPQ----GDSI 645
                 ::|.|.::.|   .||.     :|.::|..::      |:|  ..||::.|.    |.|:
  Fly  1094 VGAGIVVVLLNVFVI---GCCL-----HKRNEKRLKRGLELMPAEL--TEDSSNTPNLVIIGISL 1148

  Fly   646 ---------YTTPAGFHHHQQQQQQQQQQQHAAAAAAAALHAASQH--------------PQQQY 687
                     .:..|.|..||::::..:.....|..|...::|.|.:              ..:.|
  Fly  1149 AAFGFLLVNASLVAWFFVHQRRKKVAETTNQPAKTATIEMYAPSSYNDTVTGETLSSVSEKSESY 1213

  Fly   688 PGHGS--PEAM-KVRMAAMILQPPTRVXQAIDTTSESNEQLTQQQQQDDN-----KNKNKN---- 740
            ...||  ||.: :||..|           |.....|.::....:.|:|..     .|...|    
  Fly  1214 SNEGSSQPEYIDEVRKKA-----------ASTYLVEGSDMPPPRYQKDGTLPVIYPNNVVNACTL 1267

  Fly   741 -ENEHQNELTDQHTTSNEQRLDDSSV-------------SHNNNNNHKISS-------------- 777
             ...|.|.....|.|.::|.|....|             |:.|.|:.:..|              
  Fly  1268 PHPRHNNGSAAIHMTRDDQMLISKGVYIPSPSPAPPPDGSYYNMNSDRYLSYPPMEYPAALDFTA 1332

  Fly   778 -----------TSTTVLTNS-----DNNNTSEVAKASDSSNSEGGSSLTSSKTSSSKRDLENNMN 826
                       |.|::.||.     .|.:.:.||         |||.           .|...:.
  Fly  1333 QPMPMAHLQPMTVTSLATNGGPTLIGNGSVAAVA---------GGSG-----------TLRRGIL 1377

  Fly   827 RDIKPATAPKLLHLNVTSG--EQQEHQQPGPVDPLPVGPLTPEET-QVLLQKLSINNPFYRFRKQ 888
            |.:.....|.:.|...|.|  ..|......||: |....||...| ...|...:...|    |:.
  Fly  1378 RGVVGVPQPDVTHHTSTVGGSPMQMLHDLHPVN-LSASTLTTSTTLNGSLPTATATLP----RQP 1437

  Fly   889 SNSLKELRRKTGSDAPSVRSRSETDLGQVRGQQLMPHQQHSEAKVVVVLDSKQKEVAISRPRSSV 953
            ...||:..|.        :.:.:....|.:.|||...||...|.:|.|      .|.:|.|..|:
  Fly  1438 HGILKDPNRN--------KQQQQQQQQQQQQQQLQHQQQLLNASLVGV------GVPVSAPLGSL 1488

  Fly   954 SLKTRSVSSLSPSTNQMGDSSTVITNPF 981
                 .:.:|.|::..:|::..:.||.|
  Fly  1489 -----QILNLPPASGGLGNNLLMTTNAF 1511

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG45263NP_731246.2 I-set 53..149 CDD:254352 9/67 (13%)
Ig 198..281 CDD:299845 24/85 (28%)
IG_like 302..368 CDD:214653 20/73 (27%)
IGc2 302..357 CDD:197706 18/62 (29%)
Ig 372..446 CDD:299845 19/86 (22%)
Ig 475..568 CDD:299845 25/169 (15%)
IG_like 478..570 CDD:214653 25/168 (15%)
snsNP_001036532.1 I-set 73..170 CDD:254352
Ig 76..155 CDD:299845
IG_like 186..279 CDD:214653
Ig 197..279 CDD:299845
IG_like 296..376 CDD:214653
Ig 300..361 CDD:299845
Ig 380..454 CDD:299845
IG_like 490..573 CDD:214653 15/86 (17%)
Ig 501..560 CDD:299845 11/72 (15%)
Ig 584..666 CDD:299845 25/96 (26%)
IG_like 585..666 CDD:214653 25/95 (26%)
I-set 678..767 CDD:254352 23/93 (25%)
IGc2 692..757 CDD:197706 19/66 (29%)
Ig 788..849 CDD:143165 16/68 (24%)
Ig 885..960 CDD:143165 9/75 (12%)
FN3 967..1051 CDD:238020 15/89 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR11640
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.010

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