Protein Alignment CG45263 and kirre

DIOPT Version :9

• Sequence 1: NP_731246.2
• Gene: CG45263 / 50003
• FlyBaseID: FBgn0266801
• Length: 1876
• Species: Drosophila melanogaster
• Sequence 2: NP_001245505.1
• Gene: kirre / 31292
• FlyBaseID: FBgn0028369
• Length: 956
• Species: Drosophila melanogaster
• Alignment Length: 780
• Identity: 194/780 - (24%)
• Similarity: 299/780 - (38%)
• Gaps: 190/780 - (24%)

  Fly     2 SSQNRSKRSSR---SRSSISTSISSSGSSTKIAQLLLLIGIAVASCL-------PGSEGFQRFSE 56
            |.:|:|.:||.   |.||.|:|.||||||:           |.||..       .|..|.|.|:.
  Fly    33 SKKNKSSQSSHHGDSSSSSSSSSSSSGSSS-----------AAASSANDESKPKGGDNGGQHFAM 86

  Fly    57 QPKYTEVNPAEDTLLTCKVIDKRGTCSWQKDNKPVGIYT-----KKYEWASRMPTSDNGNVLHLD 116
            :|:...........|.|:|::|.|...|.||:..:|.:.     ::|.    |..||......||
  Fly    87 EPQDQTAVVGSRVTLPCRVMEKVGALQWTKDDFGLGQHRNLSGFERYS----MVGSDEEGDFSLD 147

  Fly   117 LHPPPVQLGGDCSLWIRSATLDFDDGLWECQVTASDFTTQDALTSQPVRLVVRVAPQRPRLEYEA 181
            ::|               ..|| ||..::|||.... ..:..:.|:..:|.|.|.|:.|:
  Fly   148 IYP---------------LMLD-DDAKYQCQVGPGP-QGEQGIRSRFAKLTVLVPPEAPK----- 190

  Fly   182 VHVPPGHNITADAGALATVKCISHYGNPPATLKWF--LGDQEISPIHPQMNATEP-DNPRTWSAT 243
              :..|..:.........::|:|..|.|.|.:.|.  ||:.....|.   ...|| .:.|..:|.
  Fly   191 --ITQGDYLVTTEDREIELECVSQGGKPAAEITWIDGLGNVLTKGIE---YVKEPLADSRRITAR 250

  Fly   244 SVVQVSAMRERHGDILRCAAYHESYTAKSVVVEAR--LDVKYAPS--IRLIGS-------PEIDL 297
            |:::::..:|.|.....|.|.:   ||......|:  |:|||||.  :.::|.       ||
  Fly   251 SILKLAPKKEHHNTTFTCQAQN---TADRTYRSAKLLLEVKYAPKVIVSVVGGALAGGKIPE--- 309

  Fly   298 EEDKDALVLRCVADANP-PASIVWRRAGRSEIASLQETLQLRPVGRR--DAGLYTCQAQNSVGTS 359
               ...::|.|.||||| ..|..|..............:.:..|.|:  || :..|:..|:||.|
  Fly   310 ---GAEVILSCQADANPHELSYRWFINDELMTGDFTTKMIIHNVSRQYHDA-IVKCEVVNAVGKS 370

  Fly   360 EQLSVQLDVKYPPKIISAGPDRLTTAPLFSPAAFECLADGNPLPSFKWVQRMAHGSKYVERGSES 424
            || |.:||:.:.| :....|..: .|.|.:..:..|...|||.|..:|:..  :..:.|...:|.
  Fly   371 EQ-SKKLDISFGP-VFRQRPVSV-EADLGATVSMRCDVAGNPEPEIEWISE--NSDQVVGVAAEL 430

  Fly   425 RLVIDNVTYEYQGEYECRATSYINGQERVAISDPVSLQVVGAPQVLRLHPSLHTVSVKRGEAASL 489
            :|   .|:.|..|.|.|:|.  :||...:...  .:|.|..|| ::..|      .|:.|.....
  Fly   431 KL---KVSSETAGRYFCKAV--VNGFPEIGAE--ATLYVKRAP-IITSH------KVQFGGVGGR 481

  Fly   490 TMVVC---ADPRPQRVAWEWGSLRLEAGSGIDRFRADDMQPDTREDCYLSTLHILHADE------ 545
            ..:.|   :.|:.:.:.|.:      .|..|:...||       .|.|:...|  |..|
  Fly   482 VKIDCLAFSIPKAEHILWSF------EGKIINMSSAD-------PDIYIFEEH--HLPEGVRAAL 531

  Fly   546 --HDSR-----PYYLVVENERGTDRHAIHLIVEGTFAEPYEMSYLMGVAGG--CMAAILLLVCLC 601
              .||:     .|...|.|..|.|...|.|:     .||..:..|:.|.|.  |:|.||::|.:.
  Fly   532 IIRDSKATHFGKYNCTVMNSYGGDSLVITLL-----REPGNIPVLLVVMGSMFCVAIILMIVMII 591

  Fly   602 IYAIKSKRCCFK----------GSTGYKSSDKDSE-KADLKSRS----DSTSGPQGDSIYTTPAG 651
            |  :..||...|          .|.|   .||.:| |::|:|::    .|.:|..|.:|..|
  Fly   592 I--VYRKRRSRKKPMPADVIPEASRG---GDKLNELKSELRSKAYDVEYSEAGGDGLAINLT--- 648

  Fly   652 FHHHQQQQQQQQQQQHAAAAAAAA---------------------LHAASQHPQQQYPGHGSPEA 695
                 |......|.:.|......|                     .|..:...||:....|||:|
  Fly   649 -----QSPMPDVQMKGATLGVPLAGPVKFDERFSGDFGGDRYNRQCHIKNLKNQQETAYKGSPQA 708

  Fly   696  695
              Fly   709  708

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45263	NP_731246.2	I-set	53..149	CDD:254352	24/100 (24%)
		Ig	198..281	CDD:299845	22/87 (25%)
		IG_like	302..368	CDD:214653	22/68 (32%)
		IGc2	302..357	CDD:197706	15/57 (26%)
		Ig	372..446	CDD:299845	19/73 (26%)
		Ig	475..568	CDD:299845	22/108 (20%)
		IG_like	478..570	CDD:214653	23/107 (21%)
kirre	NP_001245505.1	Ig	87..183	CDD:299845	26/116 (22%)
		IG_like	88..182	CDD:214653	26/114 (23%)
		C2-set_2	189..279	CDD:285423	22/102 (22%)
		Ig_2	307..379	CDD:290606	25/79 (32%)
		I-set	382..462	CDD:254352	22/90 (24%)
		IGc2	396..446	CDD:197706	14/54 (26%)
		Ig	466..561	CDD:299845	24/116 (21%)
		IG_like	478..561	CDD:214653	20/97 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11640
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010