DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG45263 and Il1r1

DIOPT Version :9

Sequence 1:	NP_731246.2	Gene:	CG45263 / 50003	FlyBaseID:	FBgn0266801	Length:	1876	Species:	Drosophila melanogaster
Sequence 2:	NP_032388.1	Gene:	Il1r1 / 16177	MGIID:	96545	Length:	576	Species:	Mus musculus

Alignment Length:	378	Identity:	87/378 - (23%)
Similarity:	146/378 - (38%)	Gaps:	79/378 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   274 VVEARLDV--KYAPSIRL-IGSPEIDLEEDKDALVLRCVADANP--PASIVWRR--------AGR 325
            ::...:||  :|...|.| :...|||:.        :|....|.  ..:|:|.:        |.|
Mouse    17 LLSLEIDVCTEYPNQIVLFLSVNEIDIR--------KCPLTPNKMHGDTIIWYKNDSKTPISADR 73

  Fly   326 -SEIASLQETLQLRPVGRRDAGLYTCQAQNS------------VGTSEQLSVQLDVKYPPKIISA 377
             |.|....|.|...|....|:|.|.|..:||            :.....|.......:|.::..|
Mouse    74 DSRIHQQNEHLWFVPAKVEDSGYYYCIVRNSTYCLKTKVTVTVLENDPGLCYSTQATFPQRLHIA 138

  Fly   378 GPDRLTTAPLFSPAAFECLADGNPLPSFKWVQR-----MAHGSKYVERGSESRLVIDNVTYEYQG 437
            |     ...|..|.......:.|.||..:|.:.     :.:.|.:   |.:.:|::.||..|::|
Mouse   139 G-----DGSLVCPYVSYFKDENNELPEVQWYKNCKPLLLDNVSFF---GVKDKLLVRNVAEEHRG 195

  Fly   438 EYECRATSYINGQERVAISDPVS--LQVVGAPQVLR-----LHPSLHTVSVKRGEAASLTMVVC- 494
            :|.||.:....|::.     ||:  :|.:...:..|     |.|...|:....|   |:..::|
Mouse   196 DYICRMSYTFRGKQY-----PVTRVIQFITIDENKRDRPVILSPRNETIEADPG---SMIQLICN 252

  Fly   495 -ADPRPQRVAWEWGSLRLEAGSGIDRFRADDMQ----PDT-REDCYLSTLHILHADEHDSR-PYY 552
             .......|.|:|....:|..   |.|.|:|.|    |.| |:...::||:|........| |:.
Mouse   253 VTGQFSDLVYWKWNGSEIEWN---DPFLAEDYQFVEHPSTKRKYTLITTLNISEVKSQFYRYPFI 314

  Fly   553 LVVENERGTDRHAIHLIVEGTFAEPYEMSYLMGVAGGCMAAILLLVCLCIYAI 605
            .||:|....:...:.||    :..|...:||:|  |..:....::.|:|||.:
Mouse   315 CVVKNTNIFESAHVQLI----YPVPDFKNYLIG--GFIILTATIVCCVCIYKV 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG45263	NP_731246.2	I-set	53..149	CDD:254352
		Ig	198..281	CDD:299845	0/6 (0%)
		IG_like	302..368	CDD:214653	18/88 (20%)
		IGc2	302..357	CDD:197706	17/77 (22%)
		Ig	372..446	CDD:299845	18/78 (23%)
		Ig	475..568	CDD:299845	24/100 (24%)
		IG_like	478..570	CDD:214653	25/99 (25%)
Il1r1	NP_032388.1	Ig	31..116	CDD:386229	22/92 (24%)
		Ig2_IL1R_like	131..220	CDD:319309	23/101 (23%)
		Ig_3	229..319	CDD:372822	25/95 (26%)
		TIR	387..542	CDD:214587
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910