Protein Alignment CG45263 and Il18rap

DIOPT Version :9

• Sequence 1: NP_731246.2
• Gene: CG45263 / 50003
• FlyBaseID: FBgn0266801
• Length: 1876
• Species: Drosophila melanogaster
• Sequence 2: NP_034683.1
• Gene: Il18rap / 16174
• MGIID: 1338888
• Length: 614
• Species: Mus musculus
• Alignment Length: 567
• Identity: 102/567 - (17%)
• Similarity: 185/567 - (32%)
• Gaps: 209/567 - (36%)

  Fly    66 AEDTLLTCKVIDKRGTCSWQKDNKPVGIYTKKYEWASRM-PTSDNGNVLHLDLHPPPVQLGGDCS 129
            ||:.:|.|.:.:               :..:|:..||:: ||..       ..|.|       ||
Mouse    39 AENFVLFCDLQE---------------LQEQKFSHASQLSPTQS-------PAHKP-------CS 74

  Fly   130 LWIRSATLDFDDGLWECQVTAS---DFTTQDALTSQPVRLVVRVAPQ---------RPRLE---- 178
                .:..|..|..|..|..:.   :..::::...|...::..:|||         |||:.
Mouse    75 ----GSQKDLSDVQWYMQPRSGSPLEEISRNSPHMQSEGMLHILAPQTNSIWSYICRPRIRSPQD 135

  Fly   179 -----YEAVHVPPGHNIT-------------ADAGAL--ATVKCISHYGNPPATLKWFLGDQEIS 223
                 ...:.|.|..|::             ...|::  .::.|.|...:|..|  |: .|..:.
Mouse   136 MACCIKTVLEVKPQRNVSCGNTAQDEQVLLLGSTGSIHCPSLSCQSDVQSPEMT--WY-KDGRLL 197

  Fly   224 PIHPQ-----------------MNATEPDNPRTWSATSVVQVSAMRERHGDILRCAAYHESYTAK 271
            |.|.:                 .:.|:.||..:|:..:||:|..:.:
Mouse   198 PEHKKNPIEMADIYVFNQGLYVCDYTQSDNVSSWTVRAVVKVRTIGK------------------ 244

  Fly   272 SVVVEARLDVKYAPSIRLIGSPEIDLEEDKDALVLRCVAD-----ANPPASIVW----------- 320
                    |:...|.|....:..:|:|..| .|.|.|...     .:.|. |.|
Mouse   245 --------DINVKPEILDPITDTLDVELGK-PLTLPCRVQFGFQRLSKPV-IKWYVKESTQEWEM 299

  Fly   321 --------RRAGRSEIASLQETLQLRPVGRRD-AGLYTCQAQNSVGTSE---QLSVQLDVKYPPK 373
                    :...::|:  ::.|:.||.|.:|| :..:.|.||||:|.:.   :|..:.:|.:...
Mouse   300 SVFEEKRIQSTFKNEV--IERTIFLREVTQRDLSRKFVCFAQNSIGNTTRTIRLRKKEEVVFVYI 362

  Fly   374 IISAGPDRLTTAPLFSPAAF-------------------ECLADGNPLPSF----KW--VQRMAH 413
            ::...   |....:...|||                   |.|.|.....:|    .|  .:..|.
Mouse   363 LLGTA---LMLVGVLVAAAFLYWYWIEVVLLCRTYKNKDETLGDKKEFDAFVSYSNWSSPETDAV 424

  Fly   414 GSKYVERGSESRLVID------NVTYEYQ-----------GEYECRATSYINGQER-VAISDPVS 460
            ||.     ||..|.::      ..||.|:           |.|.....|.|....| :.|..|
Mouse   425 GSL-----SEEHLALNLFPEVLEDTYGYRLCLLDRDVTPGGVYADDIVSIIKKSRRGIFILSP-- 482

  Fly   461 LQVVGAPQVLRLHPSLHTVSVKRGEAASLTMVV---CADPRPQRVAW 504
             ..:..|:|..|..:::...|.:    :|.:::   |:...|:.:.:
Mouse   483 -SYLNGPRVFELQAAVNLALVDQ----TLKLILIKFCSFQEPESLPY 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45263	NP_731246.2	I-set	53..149	CDD:254352	17/83 (20%)
		Ig	198..281	CDD:299845	15/99 (15%)
		IG_like	302..368	CDD:214653	20/93 (22%)
		IGc2	302..357	CDD:197706	18/79 (23%)
		Ig	372..446	CDD:299845	20/115 (17%)
		Ig	475..568	CDD:299845	4/33 (12%)
		IG_like	478..570	CDD:214653	4/30 (13%)
Il18rap	NP_034683.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	59..78		8/36 (22%)
		Ig	161..243	CDD:299845	16/84 (19%)
		Ig	255..351	CDD:299845	22/99 (22%)
		IG_like	262..352	CDD:214653	21/93 (23%)
		TIR	410..558	CDD:279864	25/127 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910