DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15864 and Y43F8B.19

DIOPT Version :9

Sequence 1:	NP_652183.2	Gene:	CG15864 / 50001	FlyBaseID:	FBgn0040528	Length:	490	Species:	Drosophila melanogaster
Sequence 2:	NP_001123044.2	Gene:	Y43F8B.19 / 6418801	WormBaseID:	WBGene00077688	Length:	243	Species:	Caenorhabditis elegans

Alignment Length:	218	Identity:	50/218 - (22%)
Similarity:	91/218 - (41%)	Gaps:	30/218 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   291 LKMEELGLDPYMVVFHDVIYDTEIDGMLNSSNF-----GLSLTDSGQK--SEVRTSKDSYIV--- 345
            :|:|.:...|.:|::.|:....::...|.....     .|.:.|.|..  |::|.:..:.:.
Worm    22 VKVEVVAWRPGLVIYRDLFTGKQVRDHLELMEHLKFEEQLVVNDDGNDIVSKIRRANGTQVFHED 86

  Fly   346 ---------DAKTLNERVTDMTGFSMEMSDPFSLINYGLGGHYMLHYDFHEYTNTTRPKQ----- 396
                     .||.|      :...:.:.::....::|..||||..|:|:..|.:.....:
Worm    87 HPAARSIWDTAKNL------LPNLNFKTAEDILALSYNPGGHYAAHHDYLLYPSEKEWDEWMRVN 145

  Fly   397 GDRIATVLFYLGEVDSGGATIFPMINITVTPKKGSAVFWYNLHNSGAMNLKSLHSACPVISGSKY 461
            |:|..|::...|..:|||||:||.:...|..|.|.|.||:|...:......|.|:.||:..|.|.
Worm   146 GNRFGTLIMAFGAAESGGATVFPRLGAAVRTKPGDAFFWFNAMGNSEQEDLSEHAGCPIYKGQKQ 210

  Fly   462 VLTKWINELPQMFVTPCMKDSNL 484
            :.|.|:....|..:...:...:|
Worm   211 ISTIWLRMRDQPILEQTLSSDSL 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15864	NP_652183.2	P4Ha_N	35..166	CDD:285528
		metallo-dependent_hydrolases	<237..>306	CDD:294200	4/14 (29%)
		P4Hc	313..467	CDD:214780	42/177 (24%)
Y43F8B.19	NP_001123044.2	P4Hc	43..217	CDD:214780	43/179 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810