Protein Alignment CG15864 and PH4alphaNE2

DIOPT Version :10

• Sequence 1: NP_652183.2
• Gene: CG15864 / 50001
• FlyBaseID: FBgn0040528
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_733378.1
• Gene: PH4alphaNE2 / 43628
• FlyBaseID: FBgn0039783
• Length: 542
• Species: Drosophila melanogaster
• Alignment Length: 539
• Identity: 164/539 - (30%)
• Similarity: 257/539 - (47%)
• Gaps: 79/539 - (14%)

  Fly     7 LTLIG--FLSACFINCQGFVKSNPKKSYAASTMELMKLLEVEDELVDNLKGYVKTLKMKFNLMER 69
            |.|:|  :||..|...:   ::|.::.:|.|.:.:..:|.:||:||.|::...:.|..|...::.
  Fly     6 LVLLGMLYLSLSFGQLR---ENNAQQRFARSVVNMDDMLNLEDDLVSNVEKLAEALARKAKTIKW 67

  Fly    70 SLIDMSRENMEMKSDYESYLGNPLNSFRLIHRLHTSWRKWYQYAIKVENNALGHIE----NARLM 130
            .:..|.:...|.||..|.: .||:::|.||..:.::|..|..|.    ...:|..|    ::|:
  Fly    68 GVFKMMKRRQEYKSSMEIF-ANPIDTFSLIRHMQSNWLMWLLYL----ETPVGQEELFFVDSRM- 126

  Fly   131 RKMLPTSSDLQQACRGIHDLMSFYDLKPEELAAGNLAGYSQPGTGLTAYDCLALGEFSVQKREDD 195
             .:||...|...|..||..:.:.|.:...::|.|.|.|. |..:.|...||||:|...:......
  Fly   127 -PLLPKYFDFIDAAEGIRKMQATYQMFSSDIAKGLLDGV-QYNSSLKPIDCLAIGLHLMNNSRWY 189

  Fly   196 LAEAWYNLSLIRFENKFDKYRVHKAWGLLLAKNKQLTDAFYHFENKPEGIIASNEV--------- 251
            .||.|.:.|:..::.|..:..:....|..||...::.......:...||.:.:.:|
  Fly   190 AAEQWISASIEAYDQKSSQTDMELLRGPKLADLCRILGQVQMKQRNHEGALQAYQVALKLSPHDP 254

  Fly   252 -------IHFKEELS---------TKQN----------CAVVVQKP---SRLHCRYNTTTTPFTR 287
                   |..|.:|:         .|.|          |:...|.|   |.|:|.||..|:||.:
  Fly   255 EIYEEYRILEKRDLTLSDIEPIEQDKDNSHERLVLPPCCSGRCQVPRNLSNLYCVYNHVTSPFLQ 319

  Fly   288 IAPLKMEELGLDPYMVVFHDVIYDTEIDGMLNSSNFGL--SLTDSGQKSEVRTSKDSYIVD---- 346
            :||:|.|.|.:||::|:.||:|...|...:..||...:  |.|.....|:..|..|:|...
  Fly   320 LAPIKTEILSIDPFVVLLHDMISQKESTLIRTSSKEHMLPSATTDPDASDDETQVDTYRTSKSVW 384

  Fly   347 --------AKTLNERVTDMTGFSMEMSDPFSLINYGLGGHYMLHYDF-----HEYTNTTRPKQGD 398
                    .|.:.||:.|.||..|..::.:.:|||||||.:..|.|.     :.:..|:     |
  Fly   385 YSSDFNDTTKKITERLGDATGLDMNSTEFYQVINYGLGGFFETHLDMLLSEKNRFNGTS-----D 444

  Fly   399 RIATVLFYLGEVDSGGATIFPMINITVTPKKGSAVFWYNLHNSGAMNLKSLHSACPVISGSKYVL 463
            ||||.||||.||..||.|.||.:|:||.|:.|||:|||||...|..::.|||:.||||.|||:|:
  Fly   445 RIATTLFYLNEVRQGGGTYFPRLNLTVFPQPGSALFWYNLDTKGNDHMGSLHTGCPVIVGSKWVM 509

  Fly   464 TKWINELPQMFVTPCMKDS 482
            :||||::.|.|..||::.|
  Fly   510 SKWINDMGQEFTRPCVESS 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15864	NP_652183.2	P4Ha_N	35..168	CDD:462433	35/136 (26%)
		P4Hc	313..467	CDD:214780	67/172 (39%)
PH4alphaNE2	NP_733378.1	P4Ha_N	33..163	CDD:462433	35/136 (26%)
		TPR repeat	175..200	CDD:276809	8/24 (33%)
		TPR_16	176..254	CDD:433202	14/77 (18%)
		NrfG	217..>260	CDD:443378	5/42 (12%)
		TPR repeat	219..249	CDD:276809	5/29 (17%)
		P4Hc	342..513	CDD:214780	67/175 (38%)