Protein Alignment CG15864 and PH4alphaEFB

DIOPT Version :9

• Sequence 1: NP_652183.2
• Gene: CG15864 / 50001
• FlyBaseID: FBgn0040528
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_733371.1
• Gene: PH4alphaEFB / 43620
• FlyBaseID: FBgn0039776
• Length: 550
• Species: Drosophila melanogaster
• Alignment Length: 533
• Identity: 160/533 - (30%)
• Similarity: 251/533 - (47%)
• Gaps: 116/533 - (21%)

  Fly    38 ELMKLLEVEDELVDNLKGYVKTLKMKFNLMERSLIDMSRENMEMKSDYESYLGNPLNSFRLIHRL 102
            |:.:|||.|..|:.||:||::..:.|.|.::..:.:..||:.:...|..:|:.||:|::.|..||
  Fly    31 EMEELLETESVLITNLEGYIRVQEDKLNFLKNKMDEYQREHSDASHDITAYVSNPINAYLLTKRL 95

  Fly   103 HTSWRKWYQYAIKVENNALGH------IENARLMRKML--PTSSDLQQACRGIHDLMSFYDLKPE 159
            .|.||       :|| |.:.|      ::|....|.:|  |:..||..|...:..|...|.|...
  Fly    96 TTDWR-------QVE-NLMEHDVGTDFLQNITQYRSLLKFPSDEDLNGAAVALLRLQDTYQLDTS 152

  Fly   160 ELAAGNLAGYSQPGTGLTAYDCLALGEFSVQKREDDLAEAWYNLSLIRFENK------------- 211
            .:|.|.|.|. |..|.:::.||..||..|....:......|.|.::.|...:
  Fly   153 SVARGKLNGI-QYSTEMSSDDCFELGRQSYVNHDYYHTVLWMNEAMARMLEEPTNHTQSFTKADI 216

  Fly   212 -----FDKYRVHKAWGLLLAKNKQL-----------TDAFYHFE-------NKPEGIIASNEVIH 253
                 |..|:.......|...|:.|           ...||..|       .|.:|...::|:.
  Fly   217 LEYLAFSTYKEGNIESALTMTNELLQLLPHHERANGNKRFYEKEIAQQLQLRKMKGDDGTDEMP- 280

  Fly   254 FKEELSTKQNCAVVVQ---------------KPS-----RLHCRYNTTTTPFTRIAPLKMEELGL 298
             |.:|...::...:..               |||     .|.|||.|...||.|:.|||:||:..
  Fly   281 -KSDLPVAKSDPAIFDMTERRAYEMLCRGELKPSPSDLRSLRCRYVTNRVPFLRLGPLKLEEVHA 344

  Fly   299 DPYMVVFHDVIYDTEID--------------------GMLNSSNFGLSLTDSGQKSEVRTSKDSY 343
            |||:|::||.:||:|||                    |.|.::|:.:|     :.:.::|.:|..
  Fly   345 DPYIVIYHDAMYDSEIDLIKRMARPRFRRATVQNSVTGALETANYRIS-----KSAWLKTQEDRV 404

  Fly   344 IVDAKTLNERVTDMTGFSMEMSDPFSLINYGLGGHYMLHYDFHEYTNTTRPKQ--------GDRI 400
            |   :|:.:|..||||..|:.::...::|||:||||..|:||     ..:.:|        |:||
  Fly   405 I---ETVVQRTADMTGLDMDSAEELQVVNYGIGGHYEPHFDF-----ARKEEQRAFEGLNLGNRI 461

  Fly   401 ATVLFYLGEVDSGGATIFPMINITVTPKKGSAVFWYNLHNSGAMNLKSLHSACPVISGSKYVLTK 465
            ||||||:.:|:.||||:|..::..:.||||:|.||.|||..|..::::.|:||||::|:|:|..|
  Fly   462 ATVLFYMSDVEQGGATVFTSLHTALFPKKGTAAFWMNLHRDGQGDVRTRHAACPVLTGTKWVSNK 526

  Fly   466 WINELPQMFVTPC 478
            ||:|..|.|..||
  Fly   527 WIHERGQEFRRPC 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15864	NP_652183.2	P4Ha_N	35..166	CDD:285528	41/135 (30%)
		metallo-dependent_hydrolases	<237..>306	CDD:294200	26/95 (27%)
		P4Hc	313..467	CDD:214780	63/181 (35%)
PH4alphaEFB	NP_733371.1	P4Ha_N	28..159	CDD:285528	41/135 (30%)
		P4Hc	356..529	CDD:214780	66/185 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461814
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	10	9.900