Protein Alignment ORC4 and orc4

DIOPT Version :10

• Sequence 1: NP_002543.2
• Gene: ORC4 / 5000
• HGNCID: 8490
• Length: 436
• Species: Homo sapiens
• Sequence 2: NP_001005654.1
• Gene: orc4 / 448135
• XenbaseID: XB-GENE-1012480
• Length: 432
• Species: Xenopus tropicalis
• Alignment Length: 434
• Identity: 315/434 - (72%)
• Similarity: 372/434 - (85%)
• Gaps: 2/434 - (0%)

Human     1 MSSRKSKSNSLIHTECLSQVQRILRERFCRQSPHSNLFGVQVQYKHLSELLKRTALHGESNSVLI 65
            ||.||||...|...||:|:|..|||:|..:.  |...|||..|:|||.||||||.:||||||.||
 Frog     1 MSKRKSKDLCLPVGECISRVHAILRQRLFQH--HGKPFGVDSQHKHLVELLKRTVVHGESNSALI 63

Human    66 IGPRGSGKTMLINHALKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNLENVVGDKVFG 130
            ||||||||:||:..||:|::.:::|.||.|||.||||||..||||||||||||:|||||||:|||
 Frog    64 IGPRGSGKSMLLKGALEEILAMKQVKENALQVRLNGLLQTTDKIALKEITRQLHLENVVGDRVFG 128

Human   131 SFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLYNLFDISQSAQTPIAVIGLTCR 195
            ||||||:|||||||.|||.|||||:|:||||||||||||||||||||||:||||||:||||||||
 Frog   129 SFAENLAFLLEALKTGDRKSSCPVLFLLDEFDLFAHHKNQTLLYNLFDIAQSAQTPVAVIGLTCR 193

Human   196 LDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEFPDKVFAEKWNENVQYLSEDR 260
            ||::||||||||||||||||||:|||.|.||::||:|:|.|||.|||..|||||||:::.|.|.:
 Frog   194 LDVMELLEKRVKSRFSHRQIHLLNSFSFIQYLEIFQEKLFLPASFPDSQFAEKWNESIKSLVESK 258

Human   261 SVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAVDLMEASQLCSMDSKANIVHGLSVLE 325
            .|:::|||.::.||::|||||||:||:.||:.|||.:||.|.:|..:|.:.||||||:|||||||
 Frog   259 MVEDILQKQYSASKDVRSLHMLLLLAVCRVSVSHPHITAADFLEVFRLRNQDSKANIMHGLSVLE 323

Human   326 ICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRKAHSVYNFEKPVVMKAFEHLQQLELIKPMER 390
            :|||||||||.|||:.||||||||:||||||:||||||||||||||||||||||.|||||||||.
 Frog   324 LCLIIAMKHLQDIYDGEPFNFQMVHNEFQKFIQRKAHSVYNFEKPVVMKAFEHLHQLELIKPMEG 388

Human   391 TSGNSQREYQLMKLLLDNTQIMNALQKYPNCPTDVRQWATSSLS 434
            .|..:|:||:||||||||||::.||||||||||||:|||.||||
 Frog   389 LSMRTQKEYRLMKLLLDNTQVIEALQKYPNCPTDVKQWAMSSLS 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ORC4	NP_002543.2	CDC6	43..>226	CDD:441083	147/182 (81%)
		ORC4_C	228..415	CDD:464223	128/186 (69%)
orc4	NP_001005654.1	CDC6	39..>214	CDD:441083	140/174 (80%)
		ORC4_C	226..413	CDD:464223	128/186 (69%)