Protein Alignment ORC4 and Orc4

DIOPT Version :10

• Sequence 1: NP_002543.2
• Gene: ORC4 / 5000
• HGNCID: 8490
• Length: 436
• Species: Homo sapiens
• Sequence 2: XP_038960388.1
• Gene: Orc4 / 295596
• RGDID: 735212
• Length: 461
• Species: Rattus norvegicus
• Alignment Length: 450
• Identity: 388/450 - (86%)
• Similarity: 414/450 - (92%)
• Gaps: 16/450 - (3%)

Human     1 MSSRKSKSNSLIHTECLSQVQRILRERFCRQSPHSNLFGVQVQYKHLSELLKRTALHGESNSVLI 65
            ||:||||:|  ||.|||||||||||||||..:|||||||||||||||.|||||||::|||||:||
  Rat    14 MSNRKSKNN--IHAECLSQVQRILRERFCHHTPHSNLFGVQVQYKHLIELLKRTAIYGESNSLLI 76

Human    66 IGPRGSGKTMLINHALKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNLENVVGDKVFG 130
            :||||||||.|:||||||||:|.::||||||||||||||.|||||||||||||||||||||||||
  Rat    77 VGPRGSGKTTLLNHALKELMQIGDMSENVLQVHLNGLLQTNDKIALKEITRQLNLENVVGDKVFG 141

Human   131 SFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLYNLFDISQSAQTPIAVIGLTCR 195
            |||||||||||||:||:|||||||||||||||||||.||||||||||||||||||||||||||||
  Rat   142 SFAENLSFLLEALQKGNRTSSCPVIFILDEFDLFAHQKNQTLLYNLFDISQSAQTPIAVIGLTCR 206

Human   196 L--------------DILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEFPDKVFA 246
            |              |||||||||||||||||||||||||.||||:||||||||||||||||:||
  Rat   207 LLILRRSELLKVYFHDILELLEKRVKSRFSHRQIHLMNSFDFPQYLKIFKEQLSLPAEFPDKIFA 271

Human   247 EKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAVDLMEASQLCSM 311
            ||||||...||||.:|.||||||||::|||:||||||||||||||.:|||||:.|||||..|||:
  Rat   272 EKWNENAHCLSEDSTVLEVLQKHFNVNKNLQSLHMLLMLALNRVTVTHPFMTSADLMEAQHLCSL 336

Human   312 DSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRKAHSVYNFEKPVVMKAF 376
            |:||:||||||||||||||||||||||||||||||||||||||||:|||||||||||||||||||
  Rat   337 DAKASIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFIQRKAHSVYNFEKPVVMKAF 401

Human   377 EHLQQLELIKPMERTSGNSQREYQLMKLLLDNTQIMNALQKYPNCPTDVRQWATSSLSWL 436
            ||||||||||||||||.||||||||:||||||||||||||||.|||||||||||||||||
  Rat   402 EHLQQLELIKPMERTSVNSQREYQLVKLLLDNTQIMNALQKYSNCPTDVRQWATSSLSWL 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ORC4	NP_002543.2	CDC6	43..>226	CDD:441083	166/196 (85%)
		ORC4_C	228..415	CDD:464223	164/186 (88%)
Orc4	XP_038960388.1	CDC6	54..>251	CDD:441083	166/196 (85%)
		ORC4_C	253..440	CDD:464223	164/186 (88%)