Protein Alignment ORC4 and Orc4

DIOPT Version :10

• Sequence 1: NP_002543.2
• Gene: ORC4 / 5000
• HGNCID: 8490
• Length: 436
• Species: Homo sapiens
• Sequence 2: NP_036088.3
• Gene: Orc4 / 26428
• MGIID: 1347043
• Length: 433
• Species: Mus musculus
• Alignment Length: 436
• Identity: 388/436 - (88%)
• Similarity: 413/436 - (94%)
• Gaps: 3/436 - (0%)

Human     1 MSSRKSKSNSLIHTECLSQVQRILRERFCRQSPHSNLFGVQVQYKHLSELLKRTALHGESNSVLI 65
            |||||:|||:  |.|||||||||||||||..||||||||||||||||.|||||||::||||||||
Mouse     1 MSSRKTKSNA--HAECLSQVQRILRERFCHHSPHSNLFGVQVQYKHLIELLKRTAIYGESNSVLI 63

Human    66 IGPRGSGKTMLINHALKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNLENVVGDKVFG 130
            :||||||||.|:|||||||||| ||||||:|||||||||.|:|||||||||||||:|||.|||||
Mouse    64 VGPRGSGKTTLLNHALKELMEI-EVSENVIQVHLNGLLQTNEKIALKEITRQLNLDNVVEDKVFG 127

Human   131 SFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLYNLFDISQSAQTPIAVIGLTCR 195
            |||||||||||||:||||||||||||||||||:|||.|||||||||||||||||||:||||||||
Mouse   128 SFAENLSFLLEALQKGDRTSSCPVIFILDEFDIFAHQKNQTLLYNLFDISQSAQTPVAVIGLTCR 192

Human   196 LDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEFPDKVFAEKWNENVQYLSEDR 260
            ||||||||||||||||||||||||||.||||:||||||||||||||||.|||:|||||..||||.
Mouse   193 LDILELLEKRVKSRFSHRQIHLMNSFDFPQYLKIFKEQLSLPAEFPDKAFAERWNENVHCLSEDS 257

Human   261 SVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAVDLMEASQLCSMDSKANIVHGLSVLE 325
            :|.|||||||:::|||:||||||||||||||.||||||:.|||||..:||:||||||||||||||
Mouse   258 TVLEVLQKHFSVNKNLQSLHMLLMLALNRVTVSHPFMTSADLMEAQHMCSLDSKANIVHGLSVLE 322

Human   326 ICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRKAHSVYNFEKPVVMKAFEHLQQLELIKPMER 390
            |||||||||||||||||||||||||||||||:||||||||||||||||||||||||||||||:||
Mouse   323 ICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFIQRKAHSVYNFEKPVVMKAFEHLQQLELIKPVER 387

Human   391 TSGNSQREYQLMKLLLDNTQIMNALQKYPNCPTDVRQWATSSLSWL 436
            ||.||||||||:||||||||||||||||.|||||||||||||||||
Mouse   388 TSVNSQREYQLVKLLLDNTQIMNALQKYSNCPTDVRQWATSSLSWL 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ORC4	NP_002543.2	CDC6	43..>226	CDD:441083	165/182 (91%)
		ORC4_C	228..415	CDD:464223	164/186 (88%)
Orc4	NP_036088.3	CDC6	41..>223	CDD:441083	165/182 (91%)
		ORC4_C	225..412	CDD:464223	164/186 (88%)