Protein Alignment Cadps and cadps2

DIOPT Version :9

• Sequence 1: NP_001245439.1
• Gene: Cadps / 49968
• FlyBaseID: FBgn0053653
• Length: 1534
• Species: Drosophila melanogaster
• Sequence 2: XP_031754847.1
• Gene: cadps2 / 100487097
• XenbaseID: XB-GENE-6033825
• Length: 1293
• Species: Xenopus tropicalis
• Alignment Length: 1407
• Identity: 770/1407 - (54%)
• Similarity: 972/1407 - (69%)
• Gaps: 173/1407 - (12%)

  Fly   101 DTGNLEVPSNGIPSGISQETLNQSVGSSRANSLPRPLSPSPSLTSEKHETAEPHGKHEREEEERK 165
            :|.::.|.|.|   |.:|.....:...|   :||||.|||||:.||..|..|   :.::||:|||
 Frog    18 ETQDVLVASGG---GAAQWDARDNAARS---TLPRPASPSPSVRSEGREEQE---RLQKEEKERK 73

  Fly   166 RRIQLYVFISRCISYPFNAKQPTDMTKRQTKISKQQLEIITQRFQAFLKGETQIMADEAFQNAVQ 230
            .|:||||||.|||:|||||||||||.:||.|::||||:.|.:|||:||.|||||:|||||.|||:
 Frog    74 NRLQLYVFIMRCIAYPFNAKQPTDMARRQQKLNKQQLQTIRERFQSFLNGETQIVADEAFCNAVR 138

  Fly   231 SYHDVFLKSERVLKMVQSGASSQHDFREVFRNNIEKRVRSLPEIDGLSKETVLTSWMAKFDIILK 295
            ||::|||||:||.:||.||..|.:||||||:.|||||||||||||||||||||:||:||:|.|.:
 Frog   139 SYYEVFLKSDRVARMVHSGGCSSNDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYR 203

  Fly   296 GTGEEDSKRP-SRMQQSLNSELILSKEQLYDMFQQILLVKKFEHQILFNALMLDSADEQAAAIRR 359
              ||||.::| :||..|..|||||||||||:||||||.::|.|||:|:||..||:||||||.|||
 Frog   204 --GEEDLRKPQNRMALSSVSELILSKEQLYEMFQQILGIQKIEHQLLYNACQLDNADEQAAQIRR 266

  Fly   360 ELDGRMQRVGEMEKNRKLMPKFVLKEMESLYVEELKSSINLLMANLESLPVSKGNMDSKYGLQKL 424
            |||||:|....:.|.|| ..||:.|||||:|:|||:||:|||||||||||||||..:.|  ||||
 Frog   267 ELDGRLQVADRIAKERK-FTKFLTKEMESMYIEELRSSVNLLMANLESLPVSKGGTEFK--LQKL 328

  Fly   425 KRYNHSTPSFLKLILRSHGSLSKLEGDSEDGSTQLTKLDVVLTFQLEVIVMEVKGLKSLAPNRIV 489
            ||..:  |:||.:            ||..|  .||:|.||||:|.||:::|||:||||:||||||
 Frog   329 KRTQN--PTFLDI------------GDEND--VQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIV 377

  Fly   490 YCTMEVENGEKLQTDQAEASKPMWDTQGDFTTTHPLPVVKVKLYTENPGMLALEDKELGKVTLKP 554
            |||||||.||||||||||||:|.|.||||||||||.|:|||||:||:.|:|||||||||||.|:|
 Frog   378 YCTMEVEGGEKLQTDQAEASRPQWGTQGDFTTTHPRPIVKVKLFTESTGVLALEDKELGKVILRP 442

  Fly   555 TPLSSKSPEWHRMIVPKNLPDQDIRIKIACRLDKPLNMKHCGYLYAIGKSVWKKWKRRYFVLVQV 619
            |..|.|:||.|:|||.||..|..::||:|.|:|||.:|||.|||||:|:.|||:||:||||||||
 Frog   443 TSNSLKTPELHKMIVHKNSQDTALKIKLAVRMDKPPHMKHSGYLYAMGQKVWKRWKKRYFVLVQV 507

  Fly   620 SQYTFAMCSYKEKKSEPSEMMQLDGYTVDYIEAASANLMFGIDLNGGRYFFNAVREGDSISFACD 684
            ||||||||:|:||||||.|:|||:||||||.:....       |.||..|||||:|||::.||.|
 Frog   508 SQYTFAMCNYREKKSEPQELMQLEGYTVDYTDPQPG-------LKGGHMFFNAVKEGDTVIFASD 565

  Fly   685 DENECSLWVMAMYRATGQSHKPTPPITQDK------NSAMSKIQGDADKARKHGMEDFISTDPCT 743
            ||.:..|||.|||||||||:||.......|      |:.....|...|:.::|||::|||.:||.
 Frog   566 DEQDRVLWVQAMYRATGQSYKPIVSNQAQKLNPKGLNTQPDTSQNYTDRGQRHGMDEFISANPCR 630

  Fly   744 FDHATLFKTLQNLTLEYRLNDPYASLGWFSPGQVFVLDEYCARYGVRGCYRHLCYLSDLLDRAEK 808
            ||||:|||.||..||::||||.|:.||||||||||||||||||||||||:||||||.:|::.||.
 Frog   631 FDHASLFKDLQIQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLKELIEHAES 695

  Fly   809 QHMIDPTLIHYSFAFCASHVHGNRPDGVGSITHEEKEKFSEIKERLRQLLEFQITNFRYCFPFGR 873
            ..:|||||:||||||||||||||||||:|::|.|||::|..||.:|..||:.||::|||||||||
 Frog   696 GAVIDPTLLHYSFAFCASHVHGNRPDGIGTVTMEEKDRFEAIKGQLASLLQNQISHFRYCFPFGR 760

  Fly   874 PEGALKATLSLLERVLMKDIVTPVPPEEVRQMIKKSLETAALVNYTRLSNKAKID------EDLR 932
            |||||||||||:||||||||.||||.|||:::::|.||.|||:|||||:..|||:      |.:.
 Frog   761 PEGALKATLSLMERVLMKDIATPVPAEEVKKIVRKCLENAALINYTRLTEYAKIEVAVKESESMN 825

  Fly   933 GDVIVPAPKKLEDLIHLAELCVDLLQQNEEHYGELRKHDKMDKKKLLKEDEDVSGGHNESEVDLI 997
            .:.   |.|||||:|:|||||:::|||||||:.|
 Frog   826 QEY---ASKKLEDVINLAELCIEVLQQNEEHHSE------------------------------- 856

  Fly   998 DSTGLISASELATAASTDGSSFRYCMPTHAVYTPPVPTAFAWFSDLLVEHAEIFWSLFAVDMDRV 1062
                                                  ||:|:.|||.|||||||:||:|||:..
 Frog   857 --------------------------------------AFSWWPDLLAEHAEIFWALFSVDMNSA 883

  Fly  1063 LSEQAPDTWDSFPLFQILNDYLRTDDNLRNGRFHQHLRDTFAPLVVRYVDLMESSIAQSIHKGFE 1127
            |..|..|:|:||||||:||::||.|..|.||:||:|:::.|.|||:||:||||||||||||||||
 Frog   884 LESQPQDSWESFPLFQLLNNFLRNDSLLCNGKFHKHVQECFMPLVIRYIDLMESSIAQSIHKGFE 948

  Fly  1128 KERWES-KGINAALNPAALNNAAQALNTAALN--PSMILCGKKDQVNFYVPKLPKQSNST--AAN 1187
            :|.|:. |.|.        ||    |.|..|.  ||:.|         .:|::|..|..:  |:.
 Frog   949 QETWQPVKSIT--------NN----LPTVTLPKVPSLTL---------NLPQIPSFSAPSWMASL 992

  Fly  1188 DEMRNGCATSEDLFWKLDALQSFIRDLHWPDAEFRQHLEQRLKMMAVDMIEQCIQRTDSSFQSWL 1252
            .:..||..|||||||||||||.|::|||||:|||..|||||||:||.||||.|::||.::|:  |
 Frog   993 YDSTNGSTTSEDLFWKLDALQVFVQDLHWPEAEFANHLEQRLKLMASDMIEACVKRTRAAFE--L 1055

  Fly  1253 KKNIAFISTDYILPSEMCAMVNVILDAKNQSFKLTTID-GIDLYK----FHAKIDDQIDKANVAM 1312
            |......|||:.:.:.:|.|.||::|||.|..||..:| |.:.||    :|:||||.|::....:
 Frog  1056 KLQRTNKSTDFRISASVCTMFNVLVDAKKQCAKLCVLDSGQEFYKQWQQYHSKIDDLIEETVKEI 1120

  Fly  1313 TQGLSGKLMSVLESTLSKLARYDEGSLIGSILSFT--------NVSSSGKDLGQGYVNFFRNNMD 1369
            ...|..|.:|||||.||||.:||||:|..||||||        .|...|.||...|:.|.|.|.|
 Frog  1121 ISLLVSKFISVLESVLSKLTKYDEGTLFSSILSFTVKAASKYVEVPKPGLDLADTYITFVRQNQD 1185

  Fly  1370 QVRGKIADDLWTLHFFEQWYSQQINMLCNWLSERVDHALHYAQVASISHIIKKIYSDFELQGVLE 1434
            .:|.|:.::::...||:||||..|.::|.||::|:|..||..|:.:|..|:||.|.||.||||::
 Frog  1186 ILREKVNEEVYIDKFFDQWYSSSIKVICVWLADRLDLQLHVYQLKTIIKIVKKTYRDFRLQGVMD 1250

  Fly  1435 DKLNSKAYQAVAQRMATEEATCA---------LTMPDACEDE 1467
            ..||||.|:.|..|:..||||.|         :||.|: :||
 Frog  1251 GTLNSKTYETVHHRLTVEEATVADSDRGGLQGVTMKDS-DDE 1291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cadps	NP_001245439.1	PH_CADPS	585..711	CDD:269940	81/125 (65%)
		PH	593..699	CDD:278594	68/105 (65%)
		DUF1041	904..1066	CDD:283860	54/167 (32%)
cadps2	XP_031754847.1	C2	357..441	CDD:214577	66/83 (80%)
		PH_CADPS	473..592	CDD:269940	81/125 (65%)
		DUF1041	791..887	CDD:399355	54/167 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	536	1.000	Domainoid score	I275
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	1405	1.000	Inparanoid score	I126
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D138870at2759
OrthoFinder	1	1.000	-	-		FOG0004367
OrthoInspector	1	1.000	-	-		otm47662
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3090
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060