DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GCS2alpha and D2096.12

DIOPT Version :9

Sequence 1:	NP_652145.1	Gene:	GCS2alpha / 49953	FlyBaseID:	FBgn0027588	Length:	924	Species:	Drosophila melanogaster
Sequence 2:	NP_001023103.1	Gene:	D2096.12 / 3565193	WormBaseID:	WBGene00017079	Length:	763	Species:	Caenorhabditis elegans

Alignment Length:	214	Identity:	40/214 - (18%)
Similarity:	66/214 - (30%)	Gaps:	78/214 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   634 TELLERWYQTGAFLPFFRAHAHIDTKRREPWLFPERTRQVIQNAVIKRYSYLPLWYTAFYELELT 698
            :|::|:.:|........|:...:..::||.|      :..|.:                 ||...
Worm   593 SEIVEQEFQKRLAEIEQRSLEQVRNEKREQW------KSKIMD-----------------ELTEK 634

  Fly   699 GEPVIRPLLAQYPLDKEAFGVDNQLLVQDRLLVRPVMQQGVSKVDVYFPAIDDKKNGDWWYDVD- 762
            ||     |||.:.|..:....|:.:..:|.                     ||:   ||||...
Worm   635 GE-----LLAFFELTSDGGRNDDYIWTEDE---------------------DDE---DWWYPTPY 670

  Fly   763 -------------TYQRQERSGYVSVPVDDFKIPVWQRGGSIVPKKERQRRASTLMLHDPYTLII 814
                         ..|||.|...........|:...:..|  :.|:|..|..|          ::
Worm   671 NHPKSTLCSQCAFRQQRQRRIAKREREQAKIKVSCLKEYG--IEKRESLRNMS----------VL 723

  Fly   815 CLDRQGKASGSLYLDDEKS 833
            ...|...|..||:.::|.|
Worm   724 TKSRIEAADKSLFRENEVS 742

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GCS2alpha	NP_652145.1	GH31_N	224..362	CDD:270212
		Glyco_hydro_31	343..792	CDD:279404	30/171 (18%)
		GH31_GANC_GANAB_alpha	362..833	CDD:269889	39/212 (18%)
D2096.12	NP_001023103.1	MCU	216..>284	CDD:309702
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1501
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900