Protein Alignment GCS2alpha and mgam

DIOPT Version :9

• Sequence 1: NP_652145.1
• Gene: GCS2alpha / 49953
• FlyBaseID: FBgn0027588
• Length: 924
• Species: Drosophila melanogaster
• Sequence 2: XP_012818887.1
• Gene: mgam / 100379714
• XenbaseID: XB-GENE-964595
• Length: 2697
• Species: Xenopus tropicalis
• Alignment Length: 977
• Identity: 244/977 - (24%)
• Similarity: 384/977 - (39%)
• Gaps: 229/977 - (23%)

  Fly     8 VAIIWALFVLADGVDPGNFKTCEQSSFCRRSRKIQGSGSKYALIPGTLNTYA------DSLTADL 66
            :.:.|..|..|.|.:                            :.|..||.|      ..|.|..
 Frog    88 INVPWCYFTNAHGYE----------------------------VKGKKNTQAGFEANLQRLPAPA 124

  Fly    67 VNKENHHQFAFKLEALVGSTFRLQIDEKQPLRPRYRVEHALKGPTQAGRIRVQRETDGEIVITSE 131
            :.:.|..|.....|....:.||.:|.:  |...|:.|.|
 Frog   125 IYENNIEQLLLAAEMQSNNRFRFKITD--PKSKRFEVPH-------------------------- 161

  Fly   132 KNKAVIHGDPFRIDFFENDVLVVSVNAKNWLYFEHLRQKAQEPTSHPAENENQQEQDAAVETPKA 196
                                             ||::    |.|...|.|.|...:  .::.|..
 Frog   162 ---------------------------------EHIK----EFTGSAASNLNYDYK--LLDKPFG 187

  Fly   197 ADTIDDPGAWEENFKSHHDSK--P--YGPEAVALDFSFPAAKVLFGIPEHADSFILKSTSGTDPY 257
            ...|.     :.|.:...||.  |  |..:.:.|....|::.: :|:.||.             :
 Frog   188 IQVIR-----KSNSRILFDSTIGPLLYADQVLQLSIKLPSSNI-YGLGEHV-------------H 233

  Fly   258 RLYNLDVFEYVVDSKMALY-------GSVPVIYG-----------HGAQRTAGVYWQNAAETWVD 304
            |.|..|.:.    .|.|::       |....:||           .|:  :.||:..|:....|.
 Frog   234 RQYKHDTYW----KKWAIFTRDEFPNGDGNNLYGAHTFFLCLEDTDGS--SFGVFLMNSNAMEVT 292

  Fly   305 IQTSETNVVSSLVNFVSGSQKTPPPAAHFMSESGIVDAFIMLGPKPMDTFKQYAALTGTHELPQL 369
            ||                    |.||..:.:..||:|.::.:|..|.....:|..|.|...:|..
 Frog   293 IQ--------------------PAPAITYRTIGGILDFYVFVGNSPEQVVMEYLELIGRPYMPAY 337

  Fly   370 FALAYHQSRWNYNDERDVTSVSAKFDEYNIPMDTMWLDIEHTDGKRYFTWDKFKFPHPLAMIKNL 434
            :.|.:|.|||.|:...:|..|..:.....||.|..:.||::.:.|:.||:||.||....:..::|
 Frog   338 WTLGFHLSRWGYSSLDEVKQVVERNRAIGIPYDVQFTDIDYMEEKKDFTYDKVKFKDLPSFAEDL 402

  Fly   435 TELGRHLVVIVDPHIKR----DNNYFFHRDCTDRGYYVKTREG-NDYEGWCWPGAASYPDFFNPV 494
            ...|:..::|:||.|..    |..|..:...|:.|.:|...:| ....|..|||...|||:.|..
 Frog   403 HAHGQRYIIILDPAIANTPLIDGPYLAYERGTNLGVWVNESDGVTPLVGKVWPGDTVYPDYTNEA 467

  Fly   495 VREYYASQYALDKFQTVTADVMLWNDMNEPSVF-------------NGPEITAP-KDLIHYGN-- 543
            ..:::. |..|:.::.|..| .:|.||||.|.|             |.|..|.. ||.:.|..
 Frog   468 CTKWWV-QECLEFYKQVPYD-GIWIDMNEVSNFVRGSNKGCASNKLNYPPYTPRIKDNVMYSKTL 530

  Fly   544 -------WE-HRDVHNLYGHMHLMGSFAGLQQRDPNQRPFILTRAHFAGSQRYAAIWTGDNFADW 600
                   |. |.|||||||:...:.:...::...|.:|..|.:|:.|||:.:|:..|.|||.|:|
 Frog   531 CMDAKQAWGLHYDVHNLYGYSMALSTEEAIKAVFPGKRSIIFSRSTFAGAGKYSGHWLGDNAANW 595

  Fly   601 SHLQHSVKMCLTEAVAGFSFCGADVGAFFGNPDTELLERWYQTGAFLPFFRAHAHIDTKRREP-- 663
            :.::.::......::.|..:.|||:..||.:...||..||.|.|||.||.|.|.....|.::|
 Frog   596 NDIKWAIPGMFEFSLFGIPYIGADICGFFDDSSEELCRRWMQVGAFYPFSRNHNAETFKHQDPAS 660

  Fly   664 ----WLFPERTRQVIQNAVIKRYSYLPLWYTAFYELELTGEPVIRPLLAQYPLDKEAFGVDNQLL 724
                .|..:.:|..:.    .||:.||..||.||:....||.|:||||.::..|.|.:|:|||.|
 Frog   661 YGADSLLVKTSRHYLN----IRYTLLPYLYTLFYKAHTKGETVVRPLLHEFYSDPETWGIDNQFL 721

  Fly   725 VQDRLLVRPVMQQGVSKVDVYFPAIDDKKNGDWWYDVDT-YQRQERSGYVSVPVDDFKIPVWQRG 788
            ....||:.|::........||.|   |.|    ||:.:| .|...|...|.:.:.:.||.:..||
 Frog   722 WGPGLLITPILNPNSVNAYVYIP---DAK----WYNYETGTQASWRKQNVDMYIPEDKIGLHVRG 779

  Fly   789 GSIVPKKERQRRASTLML--HDPYTLIICLDRQGKASGSLYLDDEKSYAYRQGQRIHVNYEFA-H 850
            |.|.|   .|:.|:|...  .:|..|||.||....|.|..:.||.:|....: ...|:.|||: .
 Frog   780 GYIFP---TQQPANTTFYSRKNPLGLIIALDDNQAARGDFFWDDGESRGTIE-SGTHILYEFSVS 840

  Fly   851 DQLVNSFVGKPKY---KTLAWIERIVIAGLEKVPSSASITVNGVSQQL-EVLHHDNTVVVRKPGV 911
            :.:::..|...||   ..|.: |.|.|.|::|..|..::...|:.|.. ..:.:|:..|:...|:
 Frog   841 NNILDMVVTHAKYTDPDNLKF-EEIKIYGVQKSVSEVTVKKGGIVQPSGHTVRYDSNKVLVITGL 904

  Fly   912 KM 913
            ::
 Frog   905 QL 906

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GCS2alpha	NP_652145.1	GH31_N	224..362	CDD:270212	30/155 (19%)
		Glyco_hydro_31	343..792	CDD:279404	149/484 (31%)
		GH31_GANC_GANAB_alpha	362..833	CDD:269889	160/508 (31%)
mgam	XP_012818887.1	Trefoil	52..95	CDD:395041	1/6 (17%)
		NtCtMGAM_N	112..221	CDD:407105	27/180 (15%)
		GH31_N	214..330	CDD:270212	30/155 (19%)
		GH31_MGAM_SI_GAA	330..693	CDD:269888	112/368 (30%)
		Trefoil	915..960	CDD:238059
		NtCtMGAM_N	989..1090	CDD:407105
		GH31_N	1083..1197	CDD:270212
		GH31_MGAM_SI_GAA	1197..1568	CDD:269888
		PRK10426	<1479..1660	CDD:236691
		Trefoil	<1813..1848	CDD:238059
		NtCtMGAM_N	1864..1977	CDD:407105
		GH31_N	1963..2084	CDD:270212
		GH31_MGAM_SI_GAA	2084..2470	CDD:269888

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000251
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910