Protein Alignment GCS2alpha and ganc

DIOPT Version :9

• Sequence 1: NP_652145.1
• Gene: GCS2alpha / 49953
• FlyBaseID: FBgn0027588
• Length: 924
• Species: Drosophila melanogaster
• Sequence 2: NP_001107305.1
• Gene: ganc / 100135094
• XenbaseID: XB-GENE-5928423
• Length: 918
• Species: Xenopus tropicalis
• Alignment Length: 898
• Identity: 394/898 - (43%)
• Similarity: 529/898 - (58%)
• Gaps: 55/898 - (6%)

  Fly    16 VLADGV---DPGNFKTCEQSSFCRRSR-KIQGSGSKYALIPGTLNTYADSLTAD-------LVNK 69
            |..:|:   |...||||.|..|.||.: .:||        |...|...:.|..|       ::|:
 Frog    18 VPVEGILTEDKKKFKTCSQIGFYRRQKLLLQG--------PSPYNADLEMLVVDNGIATLQIINQ 74

  Fly    70 ENHHQFAFKLEALVGSTFRLQIDEKQPLRPRYRVEHALKGPTQAGRIRVQRETDGEIVITSEKNK 134
            :.......::....| .|||:|:|..||:|||.|...:.....|.|:.|.:...|.||:.:....
 Frog    75 DTKVPLQVQIIPCKG-IFRLKINEISPLKPRYEVPDVIVKDLAAERLNVSQRESGCIVLENPNGA 138

  Fly   135 AVIH--GDPFRIDFFENDVLVVSVNAKNWLYFEHLRQKAQEPTSHPAENENQQEQDAAVETPKAA 197
            ..:|  ..||.:....:|.|::|:|::..||||.|    ..|.|..|..|:..|.
 Frog   139 YKLHITAQPFSVSVTADDKLLLSLNSQGLLYFESL----VSPQSKSATLESDSEV---------- 189

  Fly   198 DTIDDPGAWEENFKSHHDSKPYGPEAVALDFSFPAAKVLFGIPEHADSFILKSTSGTDPYRLYNL 262
             |.|:.|.|.|.|....|.|..||.:|.||.|....:.::|:|||||:..||:|...|.||||||
 Frog   190 -TKDEYGLWSETFGEFVDIKASGPASVGLDVSLHGFEYVYGLPEHADTHRLKNTEHNDAYRLYNL 253

  Fly   263 DVFEYVVDSKMALYGSVPVIYGHGAQRTAGVYWQNAAETWVDIQTSETNVVSSLVNFVSGSQK-- 325
            |||.|....||..|||||::..|...:|.|::|.||:||.|:|.| ......||...|..::|
 Frog   254 DVFAYKTYDKMGTYGSVPLLLAHKPTQTCGLFWLNASETLVEINT-RAAPQPSLSRSVPDTRKQR 317

  Fly   326 -TPPPAAHFMSESGIVDAFIMLGPKPMDTFKQYAALTGTHELPQLFALAYHQSRWNYNDERDVTS 389
             .|.....:||||||||.|:::||.|.|.|:|||.|||...||.||:|.|||.||||.||.||.:
 Frog   318 AIPQTEVRWMSESGIVDLFLLMGPSPQDVFRQYANLTGFQSLPPLFSLGYHQCRWNYEDEADVEA 382

  Fly   390 VSAKFDEYNIPMDTMWLDIEHTDGKRYFTWDKFKFPHPLAMIKNLTELGRHLVVIVDPHIKRDNN 454
            |...||..|||.|.:||||||||||||||||:.||.:|..|.:.|.:..|.||||.|||||.|.:
 Frog   383 VDLGFDLNNIPYDVIWLDIEHTDGKRYFTWDREKFCNPTRMQEKLKQKKRKLVVISDPHIKVDPD 447

  Fly   455 YFFHRDCTDRGYYVKTREGNDYEGWCWPGAASYPDFFNPVVREYYASQYALDKFQTVTADVMLWN 519
            |..:.:...|||:||.|.|.|:||.||||.:.|.||.||.|:::|::|||||.::..|..:.:||
 Frog   448 YSLYSEAKARGYFVKDRGGQDFEGNCWPGTSCYLDFTNPAVQDWYSAQYALDSYKDSTEVLFVWN 512

  Fly   520 DMNEPSVFNGPEITAPKDLIHYGNWEHRDVHNLYGHMHLMGSFAGLQQRDPNQ-RPFILTRAHFA 583
            ||||||||:.||:|.||:.:||..|||||:|||||....|.:|.||.||...| |||:|||:.||
 Frog   513 DMNEPSVFDSPEMTMPKNAVHYKGWEHRDLHNLYGFYQQMSTFKGLMQRSAGQERPFVLTRSFFA 577

  Fly   584 GSQRYAAIWTGDNFADWSHLQHSVKMCLTEAVAGFSFCGADVGAFFGNPDTELLERWYQTGAFLP 648
            |||||.|:|||||.|||.:|:.||.|.||.:|.|.||||||||.|.|:|:.|||.||||.|||.|
 Frog   578 GSQRYGAVWTGDNKADWEYLKISVPMLLTLSVTGISFCGADVGGFVGDPEPELLIRWYQAGAFQP 642

  Fly   649 FFRAHAHIDTKRREPWLFPERTRQVIQNAVIKRYSYLPLWYTAFYELELTGEPVIRPLLAQYPLD 713
            ||||||..|:||||||||.|....:|:..:.:||:.||.||..||...::.:||:||:..::|..
 Frog   643 FFRAHAIQDSKRREPWLFGEDNTLLIKKVIEERYTLLPFWYLLFYRAHVSAQPVMRPMWVEFPKH 707

  Fly   714 KEAFGVDNQLLVQDRLLVRPVMQQGVSKVDVYFPAIDDKKNGDWWYDVDTYQ--RQERSGYVSVP 776
            .|:|..:.|.::...|||.||:..|||.||:.||.     :|:.|||...|:  |......|.|.
 Frog   708 TESFEEETQYMLGSALLVVPVLAPGVSSVDILFPG-----SGERWYDFRKYECVRGPHRKKVKVT 767

  Fly   777 VDDFKIPVWQRGGSIVPKKERQRRASTLMLHDPYTLIICLDRQGKASGSLYLDDEKSYAYRQGQR 841
            :::  |||:||||||:|...|..|::..|...||.|.:.||.:|.|.|.|:|||..|:.|.| :.
 Frog   768 LNE--IPVFQRGGSIIPLHTRVGRSTGWMDEFPYELRVALDSKGFAEGELFLDDGHSFNYIQ-EN 829

  Fly   842 IHVNYEFAHDQLV---NSFVGKPKYKTLAWIERIVIAGLEKVPSSASITVNGV 891
            :..:.:||..:.|   :|...|.||:..:.:||:.:.|::|.|...::..:||
 Frog   830 VFAHRKFAFQRNVLSSSSADPKGKYQLKSIVERVHVMGVKKQPVEVNVHSSGV 882

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GCS2alpha	NP_652145.1	GH31_N	224..362	CDD:270212	65/140 (46%)
		Glyco_hydro_31	343..792	CDD:279404	242/451 (54%)
		GH31_GANC_GANAB_alpha	362..833	CDD:269889	248/473 (52%)
ganc	NP_001107305.1	GH31_N	225..355	CDD:270212	61/130 (47%)
		Glyco_hydro_31	336..781	CDD:279404	242/451 (54%)
		GH31_GANC_GANAB_alpha	355..822	CDD:269889	248/473 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	549	1.000	Domainoid score	I252
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D100626at2759
OrthoFinder	1	1.000	-	-		FOG0000251
OrthoInspector	1	1.000	-	-		otm49526
Panther	1	1.100	-	-	O	PTHR22762
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1016
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.110