Protein Alignment CG17450 and TEKT3

DIOPT Version :10

• Sequence 1: NP_728438.2
• Gene: CG17450 / 49952
• FlyBaseID: FBgn0040028
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_114104.1
• Gene: TEKT3 / 64518
• HGNCID: 14293
• Length: 490
• Species: Homo sapiens
• Alignment Length: 502
• Identity: 182/502 - (36%)
• Similarity: 291/502 - (57%)
• Gaps: 52/502 - (10%)

  Fly    94 NEYNERKDHRNLMESYPWSQAGAPPCMEPVMGPSIPPRVGAAYETPTKHPWRPAMAYELIQVKHM 158
            :.|.:|..|.||..|                               ...||||:..|::  ..:.
Human    31 SSYRDRFPHSNLTHS-------------------------------LSLPWRPSTYYKV--ASNS 62

  Fly   159 PEQPVTNQLTKQCFLPKGMKTDGMIFPNLVTGFDRNPQHAARAALYTRYTSNEWYNNNMTKYSES 223
            |      .:...|...:.:..:.|:           |..:.|...:||||.::||.:|:|.|.||
Human    63 P------SVAPYCTRSQRVSENTML-----------PFVSNRTTFFTRYTPDDWYRSNLTNYQES 110

  Fly   224 NMNRNLSERMRNDAVRLMRETDEKATSGQRDAGRRLGERITDLTFWRNELNAELEKLIAEMSDIN 288
            |.:|:.||::|.|..||:::..::....|.|..:.||||:.|:.||::|:..||:::|.|.:.:.
Human   111 NTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGETNALT 175

  Fly   289 ELQRQCGKALLDLEIPLHIAQECLFHRESRQGTEKVHDIVEKALLVEINNLRNSRDRLGGLH-EK 352
            :::::..:||::.|.||.:|:|||||||.|.|.:.|||.||..||.|::.:...::|: .|| :|
Human   176 DVKKRLERALMETEAPLQVARECLFHREKRMGIDLVHDEVEAQLLTEVDTILCCQERM-KLHLDK 239

  Fly   353 ISKQALDCRGAQHLLEDDVSHKESSLGIDSMCHQLNNHSRGITYYGGIEKFDPSVSTQESWAQAS 417
            ...|....|.:||.||.|:|.|:::..||..||.|.|.|.|:.|:.|:|:.|.:||..||||:.:
Human   240 AIAQLAANRASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVERVDATVSVPESWAKFT 304

  Fly   418 SEHVRRSQAERAKLSQLRSDAQSVVNSVATTVWDFWSNTNNAFDRRSQEMAEAKNRVQLHLQKVQ 482
            .:::.|||:|||..::||.|.::::...|..:|:.::..|.:|..|..|.|:|||::|.||.|..
Human   305 DDNILRSQSERAASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNRIAETADAKNKIQTHLAKTL 369

  Fly   483 QELFDMEKHLFLLQKAIQDKSGPLKVAQTRLEARSHREGVELCKDHAQDRLVQEVQDIQGAVETL 547
            ||:|..|..:..::|||:||:..||||||||:.|:.|..:|||:|.||.|||.||.::...::||
Human   370 QEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTRRPNIELCRDMAQLRLVNEVHEVDDTIQTL 434

  Fly   548 HHKLMEAEATHQGLLKTRCTLEVDLRNKVNALFIDREKCMSLRRSFP 594
            ..:|.:||.|.|.|:..:.|||.||..|.|:|:||:|||||:|:|:|
Human   435 QQRLRDAEDTLQSLVHIKATLEYDLAVKANSLYIDQEKCMSMRKSYP 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17450	NP_728438.2	Tektin	212..594	CDD:460827	161/382 (42%)
TEKT3	NP_114104.1	Tektin	99..481	CDD:460827	161/382 (42%)