DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17450 and Tekt4

DIOPT Version :9

Sequence 1:	NP_728438.2	Gene:	CG17450 / 49952	FlyBaseID:	FBgn0040028	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_001013987.1	Gene:	Tekt4 / 302991	RGDID:	1308075	Length:	447	Species:	Rattus norvegicus

Alignment Length:	468	Identity:	150/468 - (32%)
Similarity:	238/468 - (50%)	Gaps:	51/468 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   140 TKHPWRPAMAYELIQVKHMPEQPVTNQLTKQCFLPKGMKTDGMIFPNLVTGFDRNPQHAARAALY 204
            ||.|     |.:.|.|..:|::..........:...|:.|.|.                 |.|
  Rat     9 TKEP-----APQSIDVCELPQKKYEVACNTGAYTSAGLATAGF-----------------RTA-- 49

  Fly   205 TRYTSNEWYNNNMTKYSESNMNRNLSERMRNDAVRLMRETDEKATSGQRDAGRRLGERITDLTFW 269
             :|..:||:.|:..:|.::..:|:.|||.|:::.:|..||.|.|...|.|:.||:|||:.|:..|
  Rat    50 -KYLMDEWFQNSYARYHQAFADRDYSERQRHESKQLAAETGELAYRTQLDSTRRVGERLEDMHCW 113

  Fly   270 RNELNAELEKLIAEMSDINELQRQCGKALLDLEIPLHIAQECLFHRESRQGTEKVHDIVEKALLV 334
            ::||..|:::|.:|...:...:.:..:||..|.:|..||.:.|..||.||..:.|.|.||..||.
  Rat   114 KSELQREIDELSSETDQMMAQKLRLQRALDALSVPFSIATDNLQCRERRQHPDLVRDYVEVELLK 178

  Fly   335 EINNLRNSRD-------------RLGGLHEKISKQALDCRGAQHLLEDDVSHKESSLGIDSMCHQ 386
            |...:||.::             ||...|::      :|       |.:.|.|.....||..|.:
  Rat   179 ETELIRNIQELLKRTMGQAVGQIRLNREHKE------NC-------EINWSDKVEVYNIDDTCAR 230

  Fly   387 LNNHSRGITYYGGIEKFDPSVSTQESWAQASSEHVRRSQAERAKLSQLRSDAQSVVNSVATTVWD 451
            ..|.|..:.:|....||:.|.||.|:|.:.:.:.:.|::.||.....||.....::...|..:..
  Rat   231 YTNESTQVQFYPHSSKFEESASTPETWGKFTQDVLLRAERERLASVNLRKLIDCILRDTAEDLRL 295

  Fly   452 FWSNTNNAFDRRSQEMAEAKNRVQLHLQKVQQELFDMEKHLFLLQKAIQDKSGPLKVAQTRLEAR 516
            .....|.||..|.:|:.:|:.::|.||.|:..|:.|.|..:..|::||:||..||:||||||..|
  Rat   296 QCDAVNLAFSNRCEELNDARQKLQYHLLKILSEITDQEHQIAALKQAIKDKEAPLRVAQTRLYQR 360

  Fly   517 SHREGVELCKDHAQDRLVQEVQDIQGAVETLHHKLMEAEATHQGLLKTRCTLEVDLRNKVNALFI 581
            |||..||||:|:||.||:.||:::..:::.|..||.:||...:.|..:|.:||.|:..|.|:|||
  Rat   361 SHRPNVELCRDNAQFRLMSEVEELNMSLKVLKEKLQDAEQALRNLEDSRMSLEKDIAVKTNSLFI 425

  Fly   582 DREKCMSLRRSFP 594
            ||:|||:.|..:|
  Rat   426 DRQKCMTHRNRYP 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17450	NP_728438.2	Tektin	212..591	CDD:281184	134/391 (34%)
Tekt4	NP_001013987.1	Tektin	56..434	CDD:281184	134/390 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2685
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264325at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910