DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fis1 and fis1

DIOPT Version :9

Sequence 1:	NP_001137607.1	Gene:	Fis1 / 49892	FlyBaseID:	FBgn0039969	Length:	154	Species:	Drosophila melanogaster
Sequence 2:	NP_001123678.1	Gene:	fis1 / 100170430	XenbaseID:	XB-GENE-1008812	Length:	151	Species:	Xenopus tropicalis

Alignment Length:	152	Identity:	66/152 - (43%)
Similarity:	101/152 - (66%)	Gaps:	4/152 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEDLLNEVVPQEDLERFEKKYHHELELDGEVTTDTKFEYAFCLVRSRYTNDVRKGIMILEE-LAR 64
            ||.:|::.|...||.:|||||..|.: .|.::..|:||||:||:||:||:|::||..|||: |.:
Frog     1 MEAVLSDPVDTGDLLKFEKKYLAERK-SGSLSKGTQFEYAWCLIRSKYTDDIKKGARILEDLLPK 64

  Fly    65 THPDGRRDYIYYLAFGNARIKEYTSGLKYCRAFLDIE-SNDQVRSLEEYIKKEIDKEVAKGMVVA 128
            .:.:.:|||::|||..:.|:|||...|||.|..|..| :|.|...||:.|:|.:.|:...||.:.
Frog    65 GNKEEQRDYLFYLAVAHYRLKEYEKALKYVRTLLSTEPNNTQALELEKVIEKAMQKDGLVGMAIV 129

  Fly   129 GGAALVLGGILGL-GIAMARNK 149
            ||.||.:.|:.|| |:|:::.|
Frog   130 GGVALGVAGLAGLIGLAISKAK 151

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fis1	NP_001137607.1	Fis1	9..120	CDD:276936	50/112 (45%)
		TPR repeat	33..65	CDD:276936	18/32 (56%)
		TPR repeat	69..100	CDD:276936	15/30 (50%)
fis1	NP_001123678.1	Fis1	8..123	CDD:276936	51/115 (44%)
		TPR repeat	32..64	CDD:276936	18/31 (58%)
		TPR repeat	69..100	CDD:276936	15/30 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	47	1.000	Domainoid score	I11904
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H41099
Inparanoid	1	1.050	120	1.000	Inparanoid score	I4622
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1595957at2759
OrthoFinder	1	1.000	-	-		FOG0003777
OrthoInspector	1	1.000	-	-		oto102772
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6325
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.060