DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a22 and CYP705A12

DIOPT Version :9

Sequence 1:	NP_001286431.1	Gene:	Cyp6a22 / 49847	FlyBaseID:	FBgn0013773	Length:	499	Species:	Drosophila melanogaster
Sequence 2:	NP_199072.1	Gene:	CYP705A12 / 834265	AraportID:	AT5G42580	Length:	499	Species:	Arabidopsis thaliana

Alignment Length:	461	Identity:	110/461 - (23%)
Similarity:	186/461 - (40%)	Gaps:	88/461 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SEPARFPVGNMEGFRKNKHFIDIVTP--IYEKFKGNGAPFAGFFMMLRPVVLVTDLELAKQILIQ 95
            |.|:...:|::.      |.:....|  .::|......|.....:...|:|||:...:|.::...
plant    41 SPPSLPIIGHLH------HLLSSSLPHKSFQKLSFKYGPLLHLRIFNFPMVLVSSASMAYEVFRT 99

  Fly    96 DFANFEDRGMYHNERDDPL----TGHLFRIDGPKWRPLRQKMSPTFTSAKMKYMFPTVCEV---- 152
            :..|...|.:..|:  |.|    :|.:....|..|:.:::.:|       .|.:.|...|:
plant   100 NDVNVSYRFVPVNK--DSLVFGSSGFVTAPYGDYWKFMKKLIS-------TKLLRPHALELSKGN 155

  Fly   153 -GEELTQVCGELADNA-MCGILEIGDLMARYTSDVIGRCAFGVEC---NGLRNPEAE-----FAI 207
             .|||.:.|.:|...| ....:|||.:..:.|:::|.|.:.|..|   ||:.....|     ||:
plant   156 RAEELRRFCLDLQGKARKKESVEIGKVALKLTNNIICRMSMGRSCSEKNGVAERARELVNKSFAL 220

  Fly   208 MGRRAFSERRHCKLVDGFIESFPEVARFL-RMRQIHQ---------DITDFYVGIVRETVKQREE 262
            ..:..||.... |.:.|....|.|   || |:...|:         |:.|..:...|   .:..|
plant   221 SVKLFFSNMFR-KDIMGVSREFDE---FLERILVEHEENLEGDQDRDMIDHLLEAYR---NEEAE 278

  Fly   263 QGIVRSDFMNLLIEMKQRGELTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREE 327
            ..|.|....:|::|:                  |..|.|:||.|:.:.:.|:...|.:..|||.|
plant   279 YKITRKQIKSLIVEI------------------FLGGTDSSAQTIQWTMAEILNNPGVLEKLRAE 325

  Fly   328 IDQAL---RLHNGEFTYDSMQELRYMELVIAETLRKYPILPQLTRISRHLYAAKGDRHFYIEPGQ 389
            ||..:   ||    .....:..|.|::.|:.|.||.:|..|.|.|:.......|   .||:....
plant   326 IDSVVGGKRL----IQESDLPNLPYLQAVVKEGLRLHPSAPVLLRVFGESCEVK---EFYVPEKT 383

  Fly   390 MLLIPVYGIHHDPALYPEPHKFIPERFLADQLA------QRPTAAWLPFGDGPRNCIGMRFGK-- 446
            .|::.:|.::.||..:.:|..|.|||||...::      :.....::.||.|.|.|..::...
plant   384 TLVVNLYAVNRDPDSWEDPDMFKPERFLVSSISGDEEKIREQAVKYVTFGGGRRTCPAVKLAHIF 448

  Fly   447 MQTTIG 452
            |:|.||
plant   449 METAIG 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_001286431.1	p450	35..491	CDD:278495	109/459 (24%)
CYP705A12	NP_199072.1	CYP93	72..490	CDD:410748	104/424 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D467733at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010