DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a22 and LUT1

DIOPT Version :9

Sequence 1:	NP_001286431.1	Gene:	Cyp6a22 / 49847	FlyBaseID:	FBgn0013773	Length:	499	Species:	Drosophila melanogaster
Sequence 2:	NP_190881.2	Gene:	LUT1 / 824479	AraportID:	AT3G53130	Length:	539	Species:	Arabidopsis thaliana

Alignment Length:	467	Identity:	121/467 - (25%)
Similarity:	208/467 - (44%)	Gaps:	59/467 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 PIYEKFKGNGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTGHLFRI- 121
            |:| |:.....|........|..|:|:|..:||.:| :::..:. :|:. .|..:.|.|..|.|
plant   100 PLY-KWMNEYGPIYRLAAGPRNFVIVSDPAIAKHVL-RNYPKYA-KGLV-AEVSEFLFGSGFAIA 160

  Fly   122 DGPKWRPLRQKMSPTFTSAKMKYMFPTV----CEVGEELTQVCGELADNAMCGILEIGDLMARYT 182
            :||.|...|:.:.|   |...:|:...|    |:..|.|.:.....|::.....:|.  ..::.|
plant   161 EGPLWTARRRAVVP---SLHRRYLSVIVERVFCKCAERLVEKLQPYAEDGSAVNMEA--KFSQMT 220

  Fly   183 SDVIGRCAFGVECNGLR--NPEAEFAIMGRRAFSERRHCKL-----VDGFIESFPEVARFLRMRQ 240
            .||||...|....:.|.  :|..| |:......:|.|...|     :|...:..|        ||
plant   221 LDVIGLSLFNYNFDSLTTDSPVIE-AVYTALKEAELRSTDLLPYWKIDALCKIVP--------RQ 276

  Fly   241 IHQDITDFYVGIVRETVK----------QREEQGIVRSDFMN------LLIEMKQRGELTIEEMA 289
            :..:..   |.::||||:          :||.:.|...:::|      |...:..|.|::..::.
plant   277 VKAEKA---VTLIRETVEDLIAKCKEIVEREGERINDEEYVNDADPSILRFLLASREEVSSVQLR 338

  Fly   290 AQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLHNGEFTYDSMQELRYMELVI 354
            ........||.:|:.|.|.:.||.|:|..:...|.:||:|:.|...|..|  :.::||:|:...|
plant   339 DDLLSMLVAGHETTGSVLTWTLYLLSKNSSALRKAQEEVDRVLEGRNPAF--EDIKELKYITRCI 401

  Fly   355 AETLRKYPILPQLTRISRHLYAAKGDRHFYIEPGQMLLIPVYGIHHDPALYPEPHKFIPERFLAD 419
            .|::|.||..|.|.|.::......|  ::.:..||.::|.||.||....::.:..:|:||||..|
plant   402 NESMRLYPHPPVLIRRAQVPDILPG--NYKVNTGQDIMISVYNIHRSSEVWEKAEEFLPERFDID 464

  Fly   420 QLAQRPTAA---WLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCPRTDPKIEFLKSNILL 481
            ......|..   ::||..|||.|:|.:|..|:..:.|...|:..:..:.|  |..|. :.:...:
plant   465 GAIPNETNTDFKFIPFSGGPRKCVGDQFALMEAIVALAVFLQRLNVELVP--DQTIS-MTTGATI 526

  Fly   482 CPANGIYLKVQQ 493
            ...||:|:||.|
plant   527 HTTNGLYMKVSQ 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_001286431.1	p450	35..491	CDD:278495	118/463 (25%)
LUT1	NP_190881.2	PLN02936	56..539	CDD:178524	121/467 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910