DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a22 and CYP72A15

DIOPT Version :9

Sequence 1:	NP_001286431.1	Gene:	Cyp6a22 / 49847	FlyBaseID:	FBgn0013773	Length:	499	Species:	Drosophila melanogaster
Sequence 2:	NP_001325567.1	Gene:	CYP72A15 / 820697	AraportID:	AT3G14690	Length:	547	Species:	Arabidopsis thaliana

Alignment Length:	509	Identity:	125/509 - (24%)
Similarity:	219/509 - (43%)	Gaps:	76/509 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VALLLIALAVGFWFVRTRYSYW----------TRRGIGSEPARFPVGNM--------EGFRKNKH 51
            |.:.::...|.:|..||....|          .|:|:...|....||::        |...|...
plant    43 VTISVVLAVVSWWIWRTLQWVWFKPKMLEHYLRRQGLAGTPYTPLVGDLKKNFTMLSEARSKPLK 107

  Fly    52 FIDIVTP-----IYEKFKGNGAPFAGFFMMLRPVVLVTDLELAKQIL--IQDF--------ANFE 101
            ..|.::|     ..:.||..|..:..:|..: |.:.:.|.|..|::.  :.||        |...
plant   108 LTDDISPRVVPYPLQMFKTYGRTYFTWFGPI-PTITIMDPEQIKEVFNKVYDFQKPHTFPLATII 171

  Fly   102 DRGMYHNERDDPLTGHLFRIDGPKWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGE---- 162
            .:|             |...||.||...|:.::|.|...|:|.|.|.   ..:...:|.||
plant   172 AKG-------------LANYDGDKWAKHRRIINPAFHIEKIKNMVPA---FHQSCREVVGEWDQL 220

  Fly   163 LADNAMCGILEIGDLMARYTSDVIGRCAFG---VECNGLRNPEAEFAIMGRRAFSERRHCKLVDG 224
            ::|......:::...:...|:|||.|.|||   .|...:...:||.|.:..:||.:    ..:.|
plant   221 VSDKGSSCEVDVWPGLVSMTADVISRTAFGSSYKEGQRIFELQAELAQLIIQAFRK----AFIPG 281

  Fly   225 FIESFPEVARFLRMRQIHQDITDFYVGIVRETVKQREEQGIVRSDFMNLLIEMKQR----GELTI 285
            :  |:.......||:...::|.....|||.:.::.||.......|.:.:|:|...|    ..::.
plant   282 Y--SYLPTKSNRRMKAAAREIQVILRGIVNKRLRAREAGEAPSDDLLGILLESNLRQTEGNGMST 344

  Fly   286 EEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLHNGEFTYDSMQELRYM 350
            |::..:..:|:.||.:|::..|.:.:..|::....||:.|||:.|.  ..:.|...:.:.:|:.|
plant   345 EDLMEECKLFYFAGQETTSVLLVWTMVLLSQHQDWQARAREEVKQV--FGDKEPDAEGLNQLKVM 407

  Fly   351 ELVIAETLRKYPILPQLTRISRHLYAAKGDRHFYIEPGQMLLIPVYGIHHDPALY-PEPHKFIPE 414
            .:::.|.||.||.:.|||| :.|.....||  ..:..|..:.:|:..:.||..|: .:..:|.|:
plant   408 TMILYEVLRLYPPVTQLTR-AIHKELKLGD--LTLPGGVQISLPILLVQHDIELWGNDAAEFNPD 469

  Fly   415 RFLADQL--AQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCP 466
            || .|.|  |.:...::.||..|||.|||..|..::..:.:..:||.|.|.:.|
plant   470 RF-KDGLSKATKSQVSFFPFAWGPRICIGQNFALLEAKMAMALILRRFSFEISP 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_001286431.1	p450	35..491	CDD:278495	117/469 (25%)
CYP72A15	NP_001325567.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000