DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp6a22 and CYP72A7

DIOPT Version :9

Sequence 1:	NP_001286431.1	Gene:	Cyp6a22 / 49847	FlyBaseID:	FBgn0013773	Length:	499	Species:	Drosophila melanogaster
Sequence 2:	NP_188079.1	Gene:	CYP72A7 / 820689	AraportID:	AT3G14610	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	513	Identity:	126/513 - (24%)
Similarity:	218/513 - (42%)	Gaps:	81/513 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VVALLLIALAVGFWFVRTRYSYW----------TRRGIGSEPARFPVGN--------MEGFRKNK 50
            |.||.::...|..|..|.....|          .|:|:...|....||:        ||...|..
plant     6 VAALPVLVAVVVLWTWRIVKWVWIKPKMLESSLKRQGLTGTPYTPLVGDIKRNVDMMMEARSKPI 70

  Fly    51 HFIDIVTP-----IYEKFKGNGAPFAGFFMMLRPV--VLVTDLELAKQIL--IQDFANFEDRGMY 106
            :..|.:||     ..:....:|..   ||:.:.|:  :::|:.|..|::.  :.|   ||....:
plant    71 NVTDDITPRLLPLALKMLNSHGKT---FFIWIGPLPTIVITNPEQIKEVFNKVND---FEKASTF 129

  Fly   107 HNERDDPLTGHLFRIDGPKWRPLRQKMSPTFTSAKMKYMFP--------TVCEVGEELTQVCGEL 163
            ...|  .|.|.|....|.||...|:.::|.|...|:|.|.|        .||:..:..|.....|
plant   130 PLIR--LLAGGLASYKGDKWASHRRIINPAFHLEKIKNMIPAFYHCCSEVVCQWEKLFTDKESPL 192

  Fly   164 ADNAMCGILEIGDLMARYTSDVIGRCAFGVECNGLRNPEAEFAIMGRRAFSERRHCKLV-DGFIE 227
            .       :::...:...|:|||...|||   :..:..:..|.:.|..|       :|: ..|.:
plant   193 E-------VDVWPWLVNMTADVISHTAFG---SSYKEGQRIFQLQGELA-------ELIAQAFKK 240

  Fly   228 SFPEVARFL------RMRQIHQDITDFYVGIVRETVKQREEQGIVRSDFMNLLIEM----KQRGE 282
            |:...:||.      ||:.|.:::.....|||.:..|.||.......|.:.:|:|.    .|...
plant   241 SYIPGSRFYPTKSNRRMKAIDREVDVILRGIVSKREKAREAGEPANDDLLGILLESNSEESQGNG 305

  Fly   283 LTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLHNGEFTYDSMQEL 347
            :::|::..:..:|:.||.:|::..|.:.:..|:.....||:.|||:.|.|. .|.:...:|:..|
plant   306 MSVEDVMKECKLFYFAGQETTSVLLVWTMVLLSHHQDWQARAREEVMQVLG-ENNKPDMESLNNL 369

  Fly   348 RYMELVIAETLRKYPILPQLTR-ISRHLYAAKGDRHFYIEPGQMLLIPVYGIHHDPALY-PEPHK 410
            :.|.::..|.||.||.:.||.| :::.:...:    ..:..|..:.:|...:..|..|: .:...
plant   370 KVMTMIFNEVLRLYPPVAQLKRVVNKEMKLGE----LTLPAGIQIYLPTILVQRDTELWGDDAAD 430

  Fly   411 FIPERFLADQL--AQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCP 466
            |.|||| .|.|  |.:...::.|||.|||.|||..|..::..:.:..:|:.|.|.:.|
plant   431 FKPERF-RDGLSKATKNQVSFFPFGWGPRICIGQNFAMLEAKMAMALILQKFSFELSP 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_001286431.1	p450	35..491	CDD:278495	117/472 (25%)
CYP72A7	NP_188079.1	p450	21..512	CDD:299894	121/498 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910