Protein Alignment Cyp6a22 and cyp3c3

DIOPT Version :10

• Sequence 1: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001007401.2
• Gene: cyp3c3 / 492759
• ZFINID: ZDB-GENE-041114-102
• Length: 503
• Species: Danio rerio
• Alignment Length: 510
• Identity: 144/510 - (28%)
• Similarity: 245/510 - (48%)
• Gaps: 66/510 - (12%)

  Fly     1 MLDVVAL--------LLIAL--AVGFWFVRTRYSYWTRRGI-GSEPARFPVGNMEGFRKNKHFID 54
            |:|:.:|        |:|.|  ..|.|    .:.::.:.|| |..|..| .|....:.|.....|
Zfish     1 MIDLSSLSVTWTLVFLVITLLYMYGVW----PHGFFKKLGIPGPRPWPF-FGTFLSYTKGFFNFD 60

  Fly    55 IVTPIYEKFKGNGAPFAGFFMMLRPVVLVTDLELAKQILIQD-FANFEDRGMYHNERDDPLTGHL 118
            :     |..|..|..: |.:....|:::|||||:.|.|:::: ::.|.:|...:.:...||...:
Zfish    61 M-----ECAKKYGKVW-GIYDGRLPILMVTDLEMIKTIMVKECYSTFTNRREVNVDLAGPLADGI 119

  Fly   119 FRIDGPKWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCGI--------LEIG 175
            ..:...:|:.:|..:||.|||.::|.:||..      :|.     ||..:..:        ::|.
Zfish   120 SAVKDERWKRIRGTLSPYFTSGRLKEIFPIA------MTH-----ADRFIKNMQKRDHEQPVKIK 173

  Fly   176 DLMARYTSDVIGRCAFGVECNGLRNPEAEFAIMGRRAFSERRHCKLVDGFIESFPEVARFLRMRQ 240
            :::|.|:.||:...:|.|:.:.:.||:..|....:..........|: .|:..||.:|..|....
Zfish   174 EVVAPYSLDVVTSSSFSVDIDSINNPDDPFVTNIKNFLKFSLFSPLI-LFLTLFPSIANLLGKMG 237

  Fly   241 I---HQDITDFYVGIVRETVKQREEQGIVRSDFMNLLI--------------EMKQRGELTIEEM 288
            |   .:.|.:|:...:|: :|...:....|.||:.|:|              |...:| ||..|:
Zfish   238 ISVFSRSIMNFFYTALRK-IKDEHKDSNGRVDFLRLMIQNQIPDDQAKDTTSEQPVKG-LTDHEI 300

  Fly   289 AAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLHNGEFTYDSMQELRYMELV 353
            .:|:|||...|::|:::||.|.|:.||..|....||.||||:...| :...:||::.::.|:|:.
Zfish   301 LSQSFIFILGGYETTSTTLSFLLHNLATNPDCLEKLVEEIDKNFPL-DTPISYDALMKMDYLEMS 364

  Fly   354 IAETLRKYPILPQLTRISRHLYAAKGDRHFYIEPGQMLLIPVYGIHHDPALYPEPHKFIPERFLA 418
            |.|::|..|..|:|.|:.:......|   ..|....::.||.|.::.||.|:..|.:|.||||..
Zfish   365 INESMRLLPTAPRLERVCKKTVELNG---ITIPKDTLVAIPTYVLNRDPQLWDSPQEFRPERFSP 426

  Fly   419 DQLAQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCPRTDPKIE 473
            :..::....|::|||.||||||||||..|...:.:|.||:||....|..|...:|
Zfish   427 ENKSEFLQYAFMPFGLGPRNCIGMRFALMIVKLLVVKLLQNFSLETCKETQIPLE 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	126/434 (29%)
cyp3c3	NP_001007401.2	cytochrome_P450	66..495	CDD:477761	126/435 (29%)