Protein Alignment Cyp6a22 and LOC4577450

DIOPT Version :10

• Sequence 1: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: XP_001230595.3
• Gene: LOC4577450 / 4577450
• VectorBaseID: AGAMI1_004862
• Length: 505
• Species: Anopheles gambiae
• Alignment Length: 531
• Identity: 123/531 - (23%)
• Similarity: 217/531 - (40%)
• Gaps: 105/531 - (19%)

  Fly     1 MLDVVALLLIALAVGFWFVRTRYSYWTRRGIGSE---PARFP-VGNMEGF-RKNKHFIDIVTPIY 60
            |..:.||:|:...|.:|...:|.:  :.:..|.:   |..:| :|:...| ..::....::..::
Mosquito     1 MFFIPALILLLGLVLYWSKLSRKT--SAQLFGKDIPGPRSYPLIGSAHLFLGSDERTFSVINELF 63

  Fly    61 EKFKGNGAPFAGFFMML----RPVVLVTDLELAKQIL----IQDFANFE-----DRGMYHNERDD 112
            .|:        |.|..|    :..:.::|.:|.:|.|    .||.|.|.     |.|:..:...|
Mosquito    64 RKY--------GSFFKLSLGPKTFLCLSDPDLIQQALTSSACQDKAFFYRFMELDYGLVSSRYTD 120

  Fly   113 PLTGHLFRIDGPKWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELAD----------NA 167
                         |:..|:.::|.|....:...........|.:.....:.||          .|
Mosquito   121 -------------WKLYRKSLNPAFNQRILISFISIFNRCSEVMVARMAKEADRRQPFDALHYTA 172

  Fly   168 MCGILEIGDLMARYTSDVIGRCAFGVECNGLRNPEAE---------FAIMGRRAFSERRHCKLVD 223
            .|            |.:::  ||..::.:...:|:|.         .|||..|.|:...:..|:
Mosquito   173 QC------------TFEMV--CASSLKSDITHDPQAREACGAIEKMCAIMSSRLFNVLLYSDLL- 222

  Fly   224 GFIESFPEVARFLRMRQIH----QDITDFYVGIVRETVKQREEQGIVRSD--------FMNLLIE 276
                 |....|:..|:::.    :.:.....|...:..|||.|......:        |::.|:.
Mosquito   223 -----FTLTQRYREMQKVRATLGRVVNPILYGRREKLSKQRLENAHSEDEEHYRKPMVFLDQLLH 282

  Fly   277 MKQRG-ELTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLHNGEFT 340
            .::.| :|.|:|:.........||.:|:|:.:.|.|..||..|.:|.::.|||.........:.:
Mosquito   283 TQRGGRDLEIQEIENHLNTIIGAGSETTANQVAFILLMLAMHPEVQERVYEEIVSIYGSAASDLS 347

  Fly   341 YDSMQELRYMELVIAETLRKYPILPQLTRISRHLYAAK-GDRHFYIEPGQMLLIPVYGIHHDPAL 404
            |:::....|:|.||.||:|.||:.|.:.|  ..:...| ||  ..:.||..|||.:..:|.:..|
Mosquito   348 YETISAQTYLEQVIKETMRVYPVAPLIGR--ETIETVKLGD--VIVPPGVTLLINILTVHRNKEL 408

  Fly   405 YPE-PHKFIPERF---LADQLAQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFS-- 463
            :.| .|.|.|:||   ..|...|.| .:::|||.|||||||.|:|.....|.:..:||.:..|
Mosquito   409 WGERAHVFDPDRFDPAQYDAKKQHP-FSYIPFGGGPRNCIGYRYGMFAMKIMVTQVLRKYQLSTP 472

  Fly   464 VCPRTDPKIEF 474
            :.|....::.|
Mosquito   473 LTPTDSLRLSF 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	110/461 (24%)
LOC4577450	XP_001230595.3	None