Protein Alignment Cyp6a22 and LOC4577431

DIOPT Version :10

• Sequence 1: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: XP_001237417.1
• Gene: LOC4577431 / 4577431
• VectorBaseID: AGAMI1_011574
• Length: 462
• Species: Anopheles gambiae
• Alignment Length: 521
• Identity: 104/521 - (19%)
• Similarity: 185/521 - (35%)
• Gaps: 134/521 - (25%)

  Fly    22 RYSYWTRRGIGSEPARFP--------VGNMEGFRKNKHFIDIVTPIYEKFKGNGAPFAGFFMMLR 78
            |.|.|..|       |||        .|:.....:.:|.|.....:|.:||....|..|..|.|.
Mosquito    29 RRSLWVDR-------RFPSTGRTCVLYGDYGAAGRTEHRIYTTQRLYREFKSKKWPIGGALMYLT 86

  Fly    79 PVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTGHLFRIDGPKWRPLRQKMSPTFTSAKMK 143
            |.|:.||..|.:.:|.::|..        |::.......:||   .:|        .:|......
Mosquito    87 PCVIPTDPHLIEFLLNEEFGK--------NKKSSIAGSSIFR---KRW--------SSFEDEHYN 132

  Fly   144 YMFPTVCEVGEELTQVCGELADNAMC------GILEIGDLMARYTSDVIGRCAFGVECN------ 196
            .:.....|..|::.::        :|      .:..|.:|   |...:|.||.||..|.
Mosquito   133 SLVNVATEESEKVVEM--------LCTSKQPVDVKVIAEL---YAVRMIARCVFGKRCTEESHTF 186

  Fly   197 ------------------GLRNPEAEFAIMGRRAFSE-RRHCKLVDGFIESFPEVARFLRMRQIH 242
                              ....|...|....|:.... ::|..|:|..:.||        :.:..
Mosquito   187 PITEKLASQPGGIVWDVFSTAFPSTTFTATLRKLLDHFQKHPALLDELVSSF--------LTERT 243

  Fly   243 QDITDFYVGIVRETVKQREEQGIVRSDFMNLLIEMKQRGELTIEEMAAQAFIFFAAGFDTSASTL 307
            .|: :|...:.|...:.:..:.|...|...|::|:.|.             :||.|     :.|:
Mosquito   244 ADV-NFLQHLKRTEQRAKANERIAFGDTRALMLELVQN-------------VFFVA-----SGTI 289

  Fly   308 GFALYELAKQPALQAKLREEIDQALRLHNGEFTYDSMQELRYMELVIAETLRKYPILPQLTRI-- 370
            ...|:|:.....:|..|.|.:.:     :..|..|:      :|.||:|||||||.:.:::.:
Mosquito   290 IACLFEMGHNGDIQKGLHETLQR-----SNPFAVDT------LENVISETLRKYPPVGEISFVTV 343

  Fly   371 ------SRHLYAAKGDRHFYIEPGQMLLIPVYGIHHDPALYPEPHKFIPERFLADQLAQRPTAAW 429
                  |..|...|..|         :::|:|.:.||...||:|.:|.|:|.:.....|  :..:
Mosquito   344 ANNRLPSGELVVPKNTR---------VVVPIYALQHDAEHYPDPERFNPKRSIFSSSEQ--SVLY 397

  Fly   430 LPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCPRTDPKIEFLKSNILLCPANGIYLKVQQL 494
            .|.|..|.. ||.....:...:.|.::|......:.|.:...::...:..:..|...:.|.:.:.
Mosquito   398 RPLGVQPLP-IGSSLALLMVRVALSNILGRCTVRLTPESPATLKISPNQAMPYPTGRVELLISRA 461

  Fly   495 S 495
            |
Mosquito   462 S 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	89/460 (19%)
LOC4577431	XP_001237417.1	cytochrome_P450	74..454	CDD:477761	89/459 (19%)