Protein Alignment Cyp6a22 and LOC4577153

DIOPT Version :10

• Sequence 1: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: XP_061508324.1
• Gene: LOC4577153 / 4577153
• VectorBaseID: AGAMI1_013061
• Length: 501
• Species: Anopheles gambiae
• Alignment Length: 546
• Identity: 138/546 - (25%)
• Similarity: 225/546 - (41%)
• Gaps: 113/546 - (20%)

  Fly     1 MLDVVALLLIALAVGFWFVRTRY-SYWTRRGIGSEPARFP-VGN---------MEGFRKNKHFID 54
            :|.|:|.||.||.   |    :| ||....|    |.|:| :||         :|.|.:...|..
Mosquito     7 VLGVIATLLAALD---W----KYKSYEHLPG----PRRWPFIGNVVSFLGAGPVEIFDQLIAFAS 60

  Fly    55 IVTPIYEKFKGNGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTGHLF 119
            ....:|:         ..||...  .::.:..|.|:.||..  ..|..:...:::..:.:...|.
Mosquito    61 TYGKVYK---------LDFFYDY--TIIYSSPEAAEAILTS--PAFTAKSQDYDKVSEWIGNGLL 112

  Fly   120 RIDGPKWRPLRQKMSPTFTSAKMKYMFPTVCEVGE----ELTQVCGELADNAMCGILEIGDLMAR 180
            .....||...|:.::|.|....::...|......|    :|..:.|..||     .:.:...:..
Mosquito   113 ISRDQKWFTHRKVITPGFHFKILENFVPVFNRQAEAFCAKLETLTGRSAD-----AVNVFPELKL 172

  Fly   181 YTSDVIGRCAFGVECNG----------------------------LRNPEAEFAIMGRRAFSERR 217
            .|..:|...|.||..:|                            ..|.:|.|    |...:.||
Mosquito   173 LTLGIICETAMGVGMDGEGQSTQQAYYTQIVEELSSILYWRMFNVFVNIDAVF----RLTRTSRR 233

  Fly   218 HCKLVD-------GFIESFPEVARFLRMRQIHQDITDFYVGIVRETVKQREEQ---GIVRSDFMN 272
            ..:||.       |.||         |.|::::         :...|::|.|:   |..:...::
Mosquito   234 FDELVKKSWQFTLGMIE---------RRRKMNE---------LEAPVEERNEEETFGKRKRALLD 280

  Fly   273 LLIEMKQRGE-LTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLHN 336
            .|:|.:..|. ||.||:..:...|..||.||:||.:.|.||.:||.|.:|.::.:||...:....
Mosquito   281 TLLEARIDGRPLTDEEIREEVDTFTFAGHDTTASAMTFILYNVAKHPEIQERVYQEIVNEIGADF 345

  Fly   337 GEFTYDSMQELRYMELVIAETLRKYPILPQLTRISRHLYAAKGDRHFYIEPGQMLLIPVYGIHHD 401
            .|.:..::..|.||||||.|:||.:|.:|.:.||:........:|   |..|..:.|.:|.:||.
Mosquito   346 CELSLSALNNLHYMELVIKESLRLFPPVPVIARIATEDTELLAER---ITRGTSVAIDIYTMHHS 407

  Fly   402 PALYPEPHKFIPERFLADQLAQ--RPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSV 464
            ...:|:..:|.|:||...:.||  .| ..::||..|.|||||.:|.:.:....||.||:.|...:
Mosquito   408 DDYFPDAERFDPDRFEGARDAQTFNP-YTYIPFSAGSRNCIGQKFAQYELKSTLVKLLQRFQIRL 471

  Fly   465 CPRTDPKIEFLKSNILLCPANGIYLK 490
            ...:  .:..||:.|:|.||.|:.|:
Mosquito   472 ADAS--YVPILKAEIVLKPAEGLPLR 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	116/466 (25%)
LOC4577153	XP_061508324.1	None