Protein Alignment Cyp6a22 and Cyp6a18

DIOPT Version :9

• Sequence 1: NP_001286431.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001287562.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Alignment Length: 506
• Identity: 246/506 - (48%)
• Similarity: 348/506 - (68%)
• Gaps: 24/506 - (4%)

  Fly     5 VALLLIALAVGFWFVRTRYSYWTRRGIGSE---PARFPVGNMEGFRKNKHFIDIVTPIYEKFKGN 66
            ||:.|:|:..  :.:..:.:|:.||||..:   |.|   |||||::|.:...:|....|.|::.:
  Fly    10 VAVALLAIVT--YILHRKLTYFKRRGIPYDKPHPLR---GNMEGYKKTRTVHEIHQEYYNKYRNS 69

  Fly    67 GAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTGHLFRIDGPKWRPLRQ 131
            .|||.||::..:|...|.||||||||||::|:||.|:|:|:||:|||::.|||.:|||:||.||.
  Fly    70 KAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDPMSAHLFNLDGPQWRLLRS 134

  Fly   132 KMSPTFTSAKMKYMFPTVCEVGEELTQVCGE-LADNAMCGILEIGDLMARYTSDVIGRCAFGVEC 195
            |:|.||||.|||:|:|||..|.||...|..| :::|:   ||::.||:||:|.||||.||||::|
  Fly   135 KLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVSENS---ILDVRDLVARFTVDVIGTCAFGIKC 196

  Fly   196 NGLRNPEAEFAIMGRRAFSERRHCKLVDGFIESFPEVARFLRMRQIHQDITDFYVGIVRETVKQR 260
            |.||:.:|||...||||..:.||..||.|.:.|:|.:||.|.:.:....|.:||..||:|||..|
  Fly   197 NSLRDEKAEFLHFGRRALLDSRHGNLVSGLMRSYPNLARRLGLCRNTAQIQEFYQRIVKETVTLR 261

  Fly   261 EEQGIVRSDFMNLLIEMK-------QRGE----LTIEEMAAQAFIFFAAGFDTSASTLGFALYEL 314
            |::.|.|:|||::||.:|       :.||    ||::|:.||||:||.||||||:||:|||||||
  Fly   262 EKENIKRNDFMDMLIGLKNQKNMTLENGEVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFALYEL 326

  Fly   315 AKQPALQAKLREEIDQALRLHNGEFTYDSMQELRYMELVIAETLRKYPILPQLTRISRHLYAAKG 379
            ||.|::|.|:|.|:.|.|..|:.:|||:.:::|:|::.||.||||.|.|:|.:.|::...:...|
  Fly   327 AKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYLDQVINETLRHYTIVPNVDRVAAKRFVVPG 391

  Fly   380 DRHFYIEPGQMLLIPVYGIHHDPALYPEPHKFIPERFLADQLAQRPTAAWLPFGDGPRNCIGMRF 444
            :..|.||.||.::||...|||||::||||::|.||||..::.|:||:.||||||:|||||||:||
  Fly   392 NPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERFSPEESAKRPSVAWLPFGEGPRNCIGLRF 456

  Fly   445 GKMQTTIGLVSLLRNFHFSVCPRT-DPKIEFLKSNILLCPANGIYLKVQQL 494
            |:||..|||..|::||.||.|..| ||......|.|||....||.|||:.:
  Fly   457 GQMQARIGLAMLIKNFTFSPCSATPDPLTFDPHSAILLGIKGGIQLKVEAI 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_001286431.1	p450	35..491	CDD:278495	235/468 (50%)
Cyp6a18	NP_001287562.1	p450	38..504	CDD:278495	235/471 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471807
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	1	1.000	-	-		H130979
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm8426
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	11	10.900