Protein Alignment Cyp6a22 and Cyp6d4

DIOPT Version :9

• Sequence 1: NP_001286431.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_651082.1
• Gene: Cyp6d4 / 42682
• FlyBaseID: FBgn0039006
• Length: 515
• Species: Drosophila melanogaster
• Alignment Length: 528
• Identity: 175/528 - (33%)
• Similarity: 290/528 - (54%)
• Gaps: 54/528 - (10%)

  Fly     1 MLDVVALLLIALAVGFWFVRTRYSYWTRRGIGSEP-ARFPVGNMEG-FRKNKHFIDIVTPIYEKF 63
            |..::.|.:..|.:.:::::..|.||.|||...|. :..|.|.::. :|:.|.....:..:|.|.
  Fly     1 MFSLILLAVTLLTLAWFYLKRHYEYWERRGFPFEKHSGIPFGCLDSVWRQEKSMGLAIYDVYVKS 65

  Fly    64 KGNGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTGHLFRIDGPKWRP 128
            |..   ..|.:::.||.||:.|.:||:::|.||||:|.|||:|.:|..|||:.::|.:.|..||.
  Fly    66 KER---VLGIYLLFRPAVLIRDADLARRVLAQDFASFHDRGVYVDEERDPLSANIFSLRGQSWRS 127

  Fly   129 LRQKMSPTFTSAKMKYMFPTVCEVGEEL-TQVCGELADNAMCGILEIGDLMARYTSDVIGRCAFG 192
            :|..:||.|||.|:|.||.|..::|::: ..:..||.:.....: :|..:|..|..|:|....||
  Fly   128 MRHMLSPCFTSGKLKSMFSTSEDIGDKMVAHLQKELPEEGFKEV-DIKKVMQNYAIDIIASTIFG 191

  Fly   193 VECNGLRNPEAEFAIMGRRAFSERRHCKLVDGFIESFPEVARFLRMRQIHQDITDFYVG------ 251
            ::.|...||:.:|..:...|.:..|...:....|...|.:|:||           |.:|
  Fly   192 LDVNSFENPDNKFRKLVSLARANNRFNAMFGMMIFLVPSIAQFL-----------FRIGFKNPVG 245

  Fly   252 -----IVRETVKQREEQGIVRSDFMNLLIEMKQRGE---------------------LTIEEMAA 290
                 ||:|||:.||:.||||.|.:.|||:::..|:                     :::|.:.|
  Fly   246 LAMLQIVKETVEYREKHGIVRKDLLQLLIQLRNTGKIDENDEKSFSIQKTPDGHIKTISLEAITA 310

  Fly   291 QAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLHNGEFTYDSMQELRYMELVIA 355
            |||||:.||.:|:.||..|.:||||:.|.|..:|::|:|:.|..::|:.||||:.::.:::|.:.
  Fly   311 QAFIFYIAGQETTGSTAAFTIYELAQYPELLKRLQDEVDETLAKNDGKITYDSLNKMEFLDLCVQ 375

  Fly   356 ETLRKYPILPQLTRISRHLYAAKGDRHFYIEPGQMLLIPVYGIHHDPALYPEPHKFIPERFLADQ 420
            ||:||||.||.|.|.....|......| .|..|..::|.:||||||...:|:|..:.||||..:.
  Fly   376 ETIRKYPGLPILNRECTQDYTVPDTNH-VIPKGTPVVISLYGIHHDAEYFPDPETYDPERFSEES 439

  Fly   421 LAQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCPRTDPKIEFLKSNILLCPAN 485
            ....|| |::|||:|||.||..|.|::.:.:.::.:|:||:..|..|::  |||..|.|.|.|.:
  Fly   440 RNYNPT-AFMPFGEGPRICIAQRMGRINSKLAIIKILQNFNVEVMSRSE--IEFENSGIALIPKH 501

  Fly   486 GIYLKVQQ 493
            |:.:::.:
  Fly   502 GVRVRLSK 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_001286431.1	p450	35..491	CDD:278495	165/490 (34%)
Cyp6d4	NP_651082.1	p450	58..500	CDD:278495	159/460 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461191
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	237	1.000	Inparanoid score	I3345
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm8426
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	10	9.900