Protein Alignment Cyp6a22 and Cyp12e1

DIOPT Version :10

• Sequence 1: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_650003.4
• Gene: Cyp12e1 / 41272
• FlyBaseID: FBgn0037817
• Length: 522
• Species: Drosophila melanogaster
• Alignment Length: 491
• Identity: 120/491 - (24%)
• Similarity: 194/491 - (39%)
• Gaps: 83/491 - (16%)

  Fly    45 GFRKNKHFIDIVTPIYEKFKGNGAPFAGFFMMLRPVVLVTDLELAKQILIQDF-ANFEDRGMYHN 108
            |..||       .|::|.|......:...|.|  |.|..|||.|...  .||: ..|.:.|.|..
  Fly    57 GLYKN-------LPVHEMFLDMNRQYGSIFRM--PSVAGTDLVLTMN--PQDYEVIFRNEGQYPY 110

  Fly   109 ERDDPLTGHLFRI---------------DGPKWRPLRQKMSPTFTSAKMKYMFPT-VCEVGEELT 157
            .|...:..:..|:               :||.|..:|..::|.....:...::.| :.:|.:|..
  Fly   111 RRSFEVMDYFKRVHRREVFDGYDGLTSGNGPAWGKMRTAVNPILLQPRNAKLYMTNLVQVSDEFL 175

  Fly   158 Q--------VCGELADNAMCGILEIGDLMARYTSDVIGRCAFGVECNGLRNPEAEFAIMGRRAFS 214
            :        |..|:.|:.   .::|..|:......|......|:......|.:.:..::..:...
  Fly   176 ERIRIIRDPVTQEMPDDF---AVDIRHLVIESICSVALNTHLGLLGEQRNNKDIQKLVLALQDVV 237

  Fly   215 ERRHCKLVDGF-IESFPEVARFLRMRQIHQ------DITD---FYVGIVRETVKQREEQGIVRS- 268
            |.       || ::..|...::|.|....:      .|||   |::|...:.:::..:.|.:..
  Fly   238 EL-------GFQLDIMPAFWKYLPMPNFKKLMRSLDTITDFCYFHIGNALKRIEEDAKAGTLNEI 295

  Fly   269 DFMNLLIEMKQRGELTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALR 333
            .....|:|...|.:.....:.|...:|  ||.|.:..|||..|:.|:|.|..||:|.|||...|.
  Fly   296 GLETSLLEKLARFDRQTAVIIAMDLLF--AGADPTLVTLGGILFSLSKSPDKQARLLEEIRGILP 358

  Fly   334 LHNGEFTYDSMQELRYMELVIAETLRKYPILPQLTRISRHLYAAKGDRHFYIEPGQMLLIPV-YG 397
            ..:...|.::|:.|.|:...|.|.:|.|||.|...|...|.....|.|   :..|..:.|.. |.
  Fly   359 NKDSSLTIENMRNLPYLRACIKEGIRMYPIGPGTLRRMPHDVVLSGYR---VVAGTDVGIAANYQ 420

  Fly   398 IHHDPALYPEPHKFIPERFLADQ-----LAQRPTA-AWLPFGDGPRNCIGMRFGKMQTTIGLVSL 456
            :.:.....|:..:|||||:|.|:     :.:..|. .:||||.|||:|.|.|...|...|.:..|
  Fly   421 MANMEQFVPKVREFIPERWLRDESNSHLVGETATPFMYLPFGFGPRSCAGKRIVDMMLEIAISRL 485

  Fly   457 LRNF--------------HFSVCPRTDPKIEFLKSN 478
            :|||              .|.|.|....|.:|::.|
  Fly   486 VRNFKIGFDYPIENAFKAQFFVQPNIPFKFKFIERN 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	114/470 (24%)
Cyp12e1	NP_650003.4	CYP24A1-like	73..514	CDD:410677	111/459 (24%)