Protein Alignment Cyp6a22 and Cyp317a1

DIOPT Version :9

• Sequence 1: NP_001286431.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001286435.1
• Gene: Cyp317a1 / 36667
• FlyBaseID: FBgn0033982
• Length: 518
• Species: Drosophila melanogaster
• Alignment Length: 494
• Identity: 158/494 - (31%)
• Similarity: 263/494 - (53%)
• Gaps: 41/494 - (8%)

  Fly     4 VVALLLIALAVGFWFVRTRY--SYWTRRGIGSEPAR--FPVGNMEGFR------------KNKHF 52
            ::.||::.|.| ...:..||  .||....|..|..:  :|:     .|            |.:|:
  Fly     7 IIGLLVLGLLV-LLIIAARYQRDYWRYLDIPHERPKKLWPI-----IRQIMTQTLSTEAMKAEHY 65

  Fly    53 IDIVTPIYEKFKGNGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTGH 117
                :.||:||||:| ||.||:.:|:|..|:.|.||.:||:|:||.||.|||:|.|::.|||:|.
  Fly    66 ----SAIYKKFKGSG-PFCGFYALLQPRALILDRELIRQIMIKDFWNFNDRGLYCNQKSDPLSGD 125

  Fly   118 LFRIDGPKWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCGILEIGDLMARYT 182
            |:.:.|..|:.:|||:.|:....:|..::..:.|..|:|.........:.....:.|..:|.||.
  Fly   126 LYALRGESWKEMRQKLDPSLEGDRMSLLYDCLYEEAEQLLLTVNSTLMSQPHSTVHIQKIMRRYV 190

  Fly   183 SDVIGRCAFGVECNGLRN-PEAEFAIMGRRAFSERRHCKLVDGFIESFPEVARFLRMRQIHQDIT 246
            ...:.:|.||:.....:. |..:|..|...|.:..:|..|::..:..||...|.||||:..:...
  Fly   191 LSSLAKCVFGLNAEQRKTYPLEDFEQMTELALNSHKHGYLMNLMMIRFPNFCRMLRMRRTPKQAE 255

  Fly   247 DFYVGIVRETVKQREEQGIVRSDFMNLLIEM-------------KQRGELTIEEMAAQAFIFFAA 298
            ::::.::...|:|||..|..:.|::.|||::             |:.|.....|:||.|.:|..|
  Fly   256 EYFIKLLTSIVEQRETSGKPQKDYLQLLIDVKALEFITHQYEADKELGAHLQNELAAHAVVFLKA 320

  Fly   299 GFDTSASTLGFALYELAKQPALQAKLREEIDQALRLHNGEFTYDSMQELRYMELVIAETLRKYPI 363
            |::.:|:||.:.|||||..|.||.::|||:.:|:..|:|..|::.::.|.:|..||.||||.:||
  Fly   321 GYEQTANTLSYVLYELALHPELQVRVREEVKKAIERHDGHITHEGIKSLSFMGQVINETLRMHPI 385

  Fly   364 LPQLTRISRHLYAAKGDRHFYIEPGQMLLIPVYGIHHDPALYPEPHKFIPERFLADQLAQRPTAA 428
            .|.:.|.:.:.||......:.:.....|:||.:.|||||.:||:|.:|.|:|:...:.:.:....
  Fly   386 TPYILRRTLNDYAVPDHPKYILVKELFLIIPTHAIHHDPDIYPDPEEFKPDRWSGPRDSLQEQGT 450

  Fly   429 WLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCPR 467
            |..||.|.|:|||::|.::|..:.|..||..:.||:..|
  Fly   451 WFGFGVGARSCIGIQFAQLQLRLALALLLSEYEFSLNTR 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_001286431.1	p450	35..491	CDD:278495	148/461 (32%)
Cyp317a1	NP_001286435.1	p450	39..466	CDD:299894	140/436 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471831
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	10	9.900