Protein Alignment Cyp6a22 and Cyp6a8

DIOPT Version :9

• Sequence 1: NP_001286431.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Alignment Length: 500
• Identity: 240/500 - (48%)
• Similarity: 337/500 - (67%)
• Gaps: 17/500 - (3%)

  Fly     5 VALLLIALAVGFWFVRTRYSYWTRRGIGSEPARFPVGNMEGFRKNKHFIDIVTPIYEKFKGNGAP 69
            ||:.|:|:..  :::..:.:|:.||||.........||||..:|.|:..:|....|.||:.:.||
  Fly    10 VAVALLAILT--YYIHRKLTYFKRRGIPFVAPHLIRGNMEELQKTKNIHEIFQDHYNKFRESKAP 72

  Fly    70 FAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTGHLFRIDGPKWRPLRQKMS 134
            |.|||....|...|.||||||||||:||:||.::|:::||:|||::.|||.:||.:||.||.|:|
  Fly    73 FVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPISAHLFNLDGAQWRLLRNKLS 137

  Fly   135 PTFTSAKMKYMFPTVCEVGEELTQVCGE-LADNAMCGILEIGDLMARYTSDVIGRCAFGVECNGL 198
            .||||.|||.|:|||..|..|...|..| :..|:   :|||.||:||:|.||||.||||::||.|
  Fly   138 STFTSGKMKLMYPTVVSVANEFMTVMHEKVPKNS---VLEIRDLVARFTVDVIGTCAFGIQCNSL 199

  Fly   199 RNPEAEFAIMGRRAFSERRHCKLVDGFIESFPEVARFLRMRQIHQDITDFYVGIVRETVKQREEQ 263
            |:.:|||...|:|:..::||..|::||:.|:|::||.|.|.:....|.:||..||.|||..||::
  Fly   200 RDEKAEFLYFGKRSLVDKRHGTLLNGFMRSYPKLARKLGMVRTAPHIQEFYSRIVTETVAVREKE 264

  Fly   264 GIVRSDFMNLLIEMKQRGE-----------LTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQ 317
            .|.|:|||::|||:|.:.|           ||:||:.||||:||.|||:||:||:|||||||||.
  Fly   265 HIKRNDFMDMLIELKNQKEMTLENGDVVRGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAKN 329

  Fly   318 PALQAKLREEIDQALRLHNGEFTYDSMQELRYMELVIAETLRKYPILPQLTRISRHLYAAKGDRH 382
            |.:|.|:|.|:::.:..|:..|||:..::|:|:..|:.||||.|.|:|.|.|::...|...|..:
  Fly   330 PDIQDKVRAEVEEVIEQHDQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPGHPN 394

  Fly   383 FYIEPGQMLLIPVYGIHHDPALYPEPHKFIPERFLADQLAQRPTAAWLPFGDGPRNCIGMRFGKM 447
            |.||.||.::||...|||||::||||.:|.||||..::.|.||:.||||||||||||||:|||:|
  Fly   395 FVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEESAGRPSVAWLPFGDGPRNCIGLRFGQM 459

  Fly   448 QTTIGLVSLLRNFHFSVCPRTDPKIEFLKSNILLCPANGIYLKVQ 492
            |..|||..|:|||.||.|.:|...:.:...:.:|...:||||||:
  Fly   460 QARIGLALLIRNFKFSTCSKTPNPLVYDPKSFVLGVKDGIYLKVE 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_001286431.1	p450	35..491	CDD:278495	229/467 (49%)
Cyp6a8	NP_523749.2	p450	39..503	CDD:278495	229/466 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471808
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	1	1.000	-	-		H130979
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	11	10.900