Protein Alignment Cyp6a22 and Cyp6a21

DIOPT Version :9

• Sequence 1: NP_001286431.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_611003.2
• Gene: Cyp6a21 / 36665
• FlyBaseID: FBgn0033981
• Length: 504
• Species: Drosophila melanogaster
• Alignment Length: 507
• Identity: 237/507 - (46%)
• Similarity: 334/507 - (65%)
• Gaps: 17/507 - (3%)

  Fly     2 LDVVALLLIAL--AVGFWFVRTRYS--YWTRRGIGSEPARFPVGNMEGFRKNKHFIDIVTPIYEK 62
            :.|..:||.||  .||:..::.|.:  :|...||..|.....:|:|:|.|..:.|.:|.|..|.|
  Fly     1 MSVGTVLLTALLALVGYLLMKWRSTMRHWQDLGIPCEEPHILMGSMKGVRTARSFNEIWTSYYNK 65

  Fly    63 FKGNGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTGHLFRIDGPKWR 127
            |:|:| |||||:...||.|.|.:..|||||||::|..|.|||.:||..||||:|.||.:||.|||
  Fly    66 FRGSG-PFAGFYWFRRPAVFVLETSLAKQILIKEFNKFTDRGFFHNPEDDPLSGQLFLLDGQKWR 129

  Fly   128 PLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCGILEIGDLMARYTSDVIGRCAFG 192
            .:|.|:|.||||.|||||||||.:|..|.|.|.|:  :.|...::|:.:|:||:|:||||.||||
  Fly   130 TMRNKLSSTFTSGKMKYMFPTVVKVANEFTDVFGQ--NVAKSPVVEVRELLARFTTDVIGTCAFG 192

  Fly   193 VECNGLRNPEAEFAIMGRRAFSERRHCKLVDGFIESFPEVARFLRMRQIHQDITDFYVGIVRETV 257
            :||:.|::|:|||..||||:.:|:|...:..||:.|||.:||.|.|:...:.|..|::.||||||
  Fly   193 IECSSLKDPDAEFREMGRRSLTEQRLGPVGIGFVNSFPNLARRLHMKMTAEPIERFFMRIVRETV 257

  Fly   258 KQREEQGIVRSDFMNLLIEMK-------QRGE---LTIEEMAAQAFIFFAAGFDTSASTLGFALY 312
            ..||:..|.|:|||:.||::|       |.||   |||||:|||||:||||||:||::|:|||||
  Fly   258 AFREQNNIRRNDFMDQLIDLKNKPLMVSQSGESVNLTIEEIAAQAFVFFAAGFETSSTTMGFALY 322

  Fly   313 ELAKQPALQAKLREEIDQALRLHNGEFTYDSMQELRYMELVIAETLRKYPILPQLTRISRHLYAA 377
            |||:...:|.::|:|..:.:...|||..|:||::|.|::.|::||||.|.:||.|.|.....|..
  Fly   323 ELAQNQDIQNRVRKECQEVIEKCNGELNYESMKDLVYLDQVVSETLRLYTVLPVLNRECLEDYEV 387

  Fly   378 KGDRHFYIEPGQMLLIPVYGIHHDPALYPEPHKFIPERFLADQLAQRPTAAWLPFGDGPRNCIGM 442
            .|...:.|:.|..:|||...:|.|..||..|:.|.|:.|..:::.:|.:..||||||||||||||
  Fly   388 PGHPKYVIKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGM 452

  Fly   443 RFGKMQTTIGLVSLLRNFHFSVCPRTDPKIEFLKSNILLCPANGIYLKVQQL 494
            |||:||..|||..|:::|.||||.:|...:.:.|...|:...:|||||.:::
  Fly   453 RFGQMQARIGLALLIKDFKFSVCEKTTIPMTYNKEMFLIASNSGIYLKAERV 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_001286431.1	p450	35..491	CDD:278495	224/465 (48%)
Cyp6a21	NP_611003.2	p450	35..499	CDD:278495	223/466 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471806
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	1	1.000	-	-		H130979
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	11	10.900