Protein Alignment Cyp6a22 and Cyp6a20

DIOPT Version :9

• Sequence 1: NP_001286431.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_611002.3
• Gene: Cyp6a20 / 36664
• FlyBaseID: FBgn0033980
• Length: 501
• Species: Drosophila melanogaster
• Alignment Length: 503
• Identity: 237/503 - (47%)
• Similarity: 331/503 - (65%)
• Gaps: 11/503 - (2%)

  Fly     1 MLDVVALLLIALAVGFWFVRTRYSYWTRRGIGSEPARFPVGNMEGFRKNKHFIDIVTPIYEKFKG 65
            |..::.||:..:....|:|...::||.||||..:..:.|.||.....|..||.||....|.|.:.
  Fly     1 MAVMIVLLIGVITFVAWYVHQHFNYWKRRGIPHDEPKIPYGNTSELMKTVHFADIFKRTYNKLRN 65

  Fly    66 -NGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTGHLFRIDGPKWRPL 129
             ...||.||:|..:.:|:|||::.||.:||::|..|.|||::||||||||:.:|..|||.||:.|
  Fly    66 KTDGPFVGFYMYFKRMVVVTDIDFAKTVLIREFDKFHDRGVFHNERDDPLSANLVNIDGQKWKTL 130

  Fly   130 RQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCGILEIGDLMARYTSDVIGRCAFGVE 194
            |||::|||||.|||.||||:..||:||.:|.||.| :|....:||.:::||:|:||||.||||::
  Fly   131 RQKLTPTFTSGKMKTMFPTILTVGDELIRVFGETA-SADSDSMEITNVVARFTADVIGSCAFGLD 194

  Fly   195 CNGLRNPEAEFAIMGRRAFSERRHCKLVDGFIESFPEVARFLRMRQIHQDITDFYVGIVRETVKQ 259
            |:.|.:|:|:|..||..|.:||||.|.:|..:...||:|..|||:...|::.|||:.|:|:||..
  Fly   195 CHSLSDPKAKFVQMGTTAITERRHGKSMDLLLFGAPELAAKLRMKATVQEVEDFYMNIIRDTVDY 259

  Fly   260 REEQGIVRSDFMNLLIEMK-------QRGELTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQ 317
            |.:..:.|.||:::|||||       :...||..|:||||||||.|||:||::|:||||||||..
  Fly   260 RVKNNVKRHDFVDMLIEMKLKFDNGDKENGLTFNEIAAQAFIFFLAGFETSSTTMGFALYELACH 324

  Fly   318 PALQAKLREEIDQALRLHNGEFTYDSMQELRYMELVIAETLRKYPILPQLTRISRHLYAAKGDRH 382
            ..:|.|||.||:..|:.|||:..||||:|:.|:|.||.||:||.|::..|.|::...|.....:
  Fly   325 QDIQDKLRTEINTVLKQHNGKLDYDSMREMTYLEKVIDETMRKRPVVGHLIRVATQHYQHTNPK- 388

  Fly   383 FYIEPGQMLLIPVYGIHHDPALYPEPHKFIPERFLADQLAQRPTAAWLPFGDGPRNCIGMRFGKM 447
            :.||.|..:::|...|||||..||||.|||||||..||:.|||...:||||||||||||:|||:|
  Fly   389 YNIEKGTGVIVPTLAIHHDPEFYPEPEKFIPERFDEDQVQQRPACTFLPFGDGPRNCIGLRFGRM 453

  Fly   448 QTTIGLVSLLRNFHFSVCP-RTDPKIEFLKSNILLCPANGIYLKVQQL 494
            |..:|:..|:.||.|...| :|...:|:...:.||....||:|||.::
  Fly   454 QVIVGMALLIHNFKFEFHPTKTVVPLEYRTDDFLLSSKGGIHLKVTRV 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_001286431.1	p450	35..491	CDD:278495	224/464 (48%)
Cyp6a20	NP_611002.3	p450	32..496	CDD:278495	223/465 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	1	1.000	-	-		H130979
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm8426
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	10	9.970