Protein Alignment Cyp6a22 and Cyp6a23

DIOPT Version :9

• Sequence 1: NP_001286431.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Alignment Length: 503
• Identity: 239/503 - (47%)
• Similarity: 336/503 - (66%)
• Gaps: 11/503 - (2%)

  Fly     1 MLDVVALLLIALAVGFWFVRTRYSYWTRRGIGSEPARFPVGNMEGFRKNKHFIDIVTPIYEKFKG 65
            :|.::|||:..|   .:..|.|:.||.||||..:......|||:.:.|.:|...|....|.|:|.
  Fly     4 LLTLIALLVSLL---LFMARRRHGYWQRRGIPHDVPHPIYGNMKDWPKKRHIAMIFRDYYTKYKR 65

  Fly    66 NGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTGHLFRIDGPKWRPLR 130
            :..|||||:.......::|||||.|::||:||.:||:||:::||.||||:..||.|:|.|||.||
  Fly    66 SVYPFAGFYFFFTRSAVITDLELVKRVLIKDFNHFENRGIFYNEIDDPLSATLFSIEGQKWRHLR 130

  Fly   131 QKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCGILEIGDLMARYTSDVIGRCAFGVEC 195
            .|::|||||.|||.|||.:.:||||:.::...........:|||.||:||||:||||.||||:.|
  Fly   131 HKLTPTFTSGKMKNMFPIIVKVGEEMEKIFSAKTTTGEGQVLEIVDLVARYTADVIGNCAFGLNC 195

  Fly   196 NGLRNPEAEFAIMGRRAFSERRHCKLVDGFIESFPEVARFLRMRQIHQDITDFYVGIVRETVKQR 260
            |.|:||.|||..:|:||..|||:..|:|..|..||:::|.||::...||:.|||..|||.|:..|
  Fly   196 NSLQNPNAEFVTIGKRAIIERRYGGLLDFLIFGFPKLSRRLRLKLNVQDVEDFYTSIVRNTIDYR 260

  Fly   261 EEQGIVRSDFMNLLIEMKQRGE-------LTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQP 318
            ......|.|||:.||||.::.:       |:..|:.|||||||.|||:||::|:||||||||...
  Fly   261 LRTNEKRHDFMDSLIEMYEKEQAGNTEDGLSFNEILAQAFIFFVAGFETSSTTMGFALYELALDQ 325

  Fly   319 ALQAKLREEIDQALRLHNGEFTYDSMQELRYMELVIAETLRKYPILPQLTRISRHLYAAKGDRHF 383
            .:|.:||.||:..|..||.||||:.::|::|:|.|:.|||||||:|..|||:::..::.: |..:
  Fly   326 DIQDQLRAEINNVLSKHNNEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDFSPE-DPKY 389

  Fly   384 YIEPGQMLLIPVYGIHHDPALYPEPHKFIPERFLADQLAQRPTAAWLPFGDGPRNCIGMRFGKMQ 448
            :|..|..::||..|||:||.:||||.||.||||..:.:|.||:..|||||:|||||||:|||.||
  Fly   390 FIAKGTTVVIPALGIHYDPEIYPEPEKFKPERFTDEAIAARPSCTWLPFGEGPRNCIGLRFGLMQ 454

  Fly   449 TTIGLVSLLRNFHFSVCPRTDPKIEFLKSNILLCPANGIYLKVQQLSQ 496
            ..:||..|:|.:.|||...|...::|:..:|||...|||:|||::||:
  Fly   455 ACVGLAYLIRGYKFSVSTETQIPMKFVVKSILLSAENGIHLKVEKLSK 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_001286431.1	p450	35..491	CDD:278495	222/462 (48%)
Cyp6a23	NP_611000.2	p450	36..495	CDD:278495	221/459 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471800
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	1	1.000	-	-		H130979
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	11	10.900