Protein Alignment Cyp6a22 and Cyp6g1

DIOPT Version :9

• Sequence 1: NP_001286431.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001286335.1
• Gene: Cyp6g1 / 36316
• FlyBaseID: FBgn0025454
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 519
• Identity: 180/519 - (34%)
• Similarity: 279/519 - (53%)
• Gaps: 42/519 - (8%)

  Fly     1 MLDVVALLLIALAVGFWFVRTRYSYWTRRGIGSEPARFPVGNME-GFRKNKHFIDIVTPIYEKFK 64
            :|.||...|:||..  ||.| .:|||.|:||...|....:||.: .|:....|...::.||...:
  Fly     6 VLFVVVAALVALYT--WFQR-NHSYWQRKGIPYIPPTPIIGNTKVVFKMENSFGMHLSEIYNDPR 67

  Fly    65 GNGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPL-TGHLFRIDGPKWRP 128
            .......|.:.|.:|.:::.|:||.|.|||:||..|.:|....:...||| ..:||.:....|:.
  Fly    68 LKDEAVVGIYSMNKPGLIIRDIELIKSILIKDFNRFHNRYARCDPHGDPLGYNNLFFVRDAHWKG 132

  Fly   129 LRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELA------DNAMCGILEIGDLMARYTSDVIG 187
            :|.|::|.|||.|:|.|:..:.|:|::|     |||      .|:...|.||.::.|::::|.|.
  Fly   133 IRTKLTPVFTSGKVKQMYTLMQEIGKDL-----ELALQRRGEKNSGSFITEIKEICAQFSTDSIA 192

  Fly   188 RCAFGVECNGLRNPEAEFAIMGRRAFSERRHCKLVDGFIESF-PEVARFLRMRQIHQDITDFYVG 251
            ..|||:..|.|.||.|||...||:.|: ....:..|.|:..| |::...:|::....|.:.|...
  Fly   193 TIAFGIRANSLENPNAEFRNYGRKMFT-FTVARAKDFFVAFFLPKLVSLMRIQFFTADFSHFMRS 256

  Fly   252 IVRETVKQREEQGIVRSDFMNLLIEMKQRGELTIEE-----------MAAQAFIFFAAGFDTSAS 305
            .:...:::||..|::|:|.:::|:.:  |.|...|.           :.|||.:||.|||:||:|
  Fly   257 TIGHVMEERERSGLLRNDLIDVLVSL--RKEAAAEPSKPHYAKNQDFLVAQAGVFFTAGFETSSS 319

  Fly   306 TLGFALYELAKQPALQAKLREEIDQALRLHNGEFTYDSMQELRYMELVIAETLRKYPILPQLTRI 370
            |:.|||||:||.|.:|.:||:||::||....|..:|:.:|.|.|:.:|:.|.||.||:||.|
  Fly   320 TMSFALYEMAKHPEMQKRLRDEINEALVEGGGSLSYEKIQSLEYLAMVVDEVLRMYPVLPFL--- 381

  Fly   371 SRHLYAAKGD-----RHFY---IEPGQMLLIPVYGIHHDPALYPEPHKFIPERFLADQLAQRPTA 427
            .|...:.:|.     :.||   :|.|..:.||:|.:||||..:..|.:|.||||...........
  Fly   382 DREYESVEGQPDLSLKPFYDYTLENGTPVFIPIYALHHDPKYWTNPSQFDPERFSPANRKNIVAM 446

  Fly   428 AWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCPRTDPKIEFLKSNILLCPANGIYLKV 491
            |:.|||.||.||||.|.|.:|:.:||||||:|.....|..|...::|.....:|....||:|::
  Fly   447 AYQPFGSGPHNCIGSRIGLLQSKLGLVSLLKNHSVRNCEATMKDMKFDPKGFVLQADGGIHLEI 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_001286431.1	p450	35..491	CDD:278495	165/483 (34%)
Cyp6g1	NP_001286335.1	p450	56..508	CDD:278495	159/462 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461095
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	10	9.900