Protein Alignment Cyp6a22 and Cyp4e2

DIOPT Version :9

• Sequence 1: NP_001286431.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001286196.1
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 565
• Identity: 135/565 - (23%)
• Similarity: 222/565 - (39%)
• Gaps: 131/565 - (23%)

  Fly     7 LLLIALAVGFWFVRTRYSYWTRRGIGSE---PARFP-VGNMEGFRKN-KHFIDIVTPIYEKF-KG 65
            |||:|.        ...|.:.||.:.::   |...| :||.....|| ...:|.|...:.:: |.
  Fly    13 LLLVAY--------LELSTFRRRRVLNKFNGPRGLPLMGNAHQMGKNPSEILDTVFSWWHQYGKD 69

  Fly    66 NGAPFAGFFMMLRPVVLVTD---LE--LAKQILIQDFANFEDRGMYHNERDDPLTG-HLFRIDGP 124
            |...:.|.:..    ||||.   ||  |:.|.||.....::   :.|     |..| .|....|.
  Fly    70 NFVFWIGTYSN----VLVTSSKYLEFILSSQTLITKSDIYQ---LTH-----PWLGLGLLTSTGS 122

  Fly   125 KWRPLRQKMSPTF--------------TSAKMKYMFPTVCEVGEELTQVCGELADNAMCGILEIG 175
            ||...|:.::|.|              .|.|......||.            ..||    |.:..
  Fly   123 KWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVA------------AGDN----IFDFQ 171

  Fly   176 DLMARYTSDVIGRCAFGVECNGLRNPEAEFA--------IMGRRAFSERRHCKLVDGFIESFPEV 232
            :.....|.|||...|.||..|.:.|..:...        .:..|||...:..:|:......:|..
  Fly   172 EQAHYLTLDVICDTAMGVSINAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAY 236

  Fly   233 ARFLRMRQIHQDITDFYVGIVRETVKQREEQGIVRSD-----------FMNLLIEMKQRGE-LTI 285
            :|.|:..|      ||...|:.:.: :..:.|.|.::           |::.|:.....|. |..
  Fly   237 SRTLKTLQ------DFTNEIIAKRI-EAHKSGAVSTNAGDEFTRKKMAFLDTLLSSTIDGRPLNS 294

  Fly   286 EEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLHNGEF----TYDSMQE 346
            :|:..:...|...|.||:.|.:.||:|.|::....|.||.:|  |...:.|.|.    |:..:.:
  Fly   295 KELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKE--QREVMGNSELGRDATFQEISQ 357

  Fly   347 LRYMELVIAETLRKYPILPQLTRISRHLYAAKGDRHFYIEPGQMLLIPVYGIHHDPALYPEPHKF 411
            ::|::|.|.|..|.||.:|.:.|.:...|...||   .:..|..|.:.:..:.::..::.:||||
  Fly   358 MKYLDLFIKEAQRVYPSVPFIGRFTEKDYVIDGD---LVPKGTTLNLGLVMLGYNEKVFKDPHKF 419

  Fly   412 IPERFLADQLAQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCPRTD------- 469
            .||||   :|.:.....::||..|||||||.:|..::....:..::||  |.|.|..|
  Fly   420 RPERF---ELEKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRN--FEVLPALDELVSKDG 479

  Fly   470 --------PKIE-------------FLKSNILLCPANGIYLKVQQ 493
                    |..|             .|.:.:.|...||:|:::::
  Fly   480 YISTTIGLPDAERKKRDPYRHKYDPILSAVLTLKSENGLYIRLKE 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_001286431.1	p450	35..491	CDD:278495	128/530 (24%)
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	119/478 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910