Protein Alignment Cyp6a22 and Cyp4ad1

DIOPT Version :10

• Sequence 1: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_610380.1
• Gene: Cyp4ad1 / 35821
• FlyBaseID: FBgn0033292
• Length: 516
• Species: Drosophila melanogaster
• Alignment Length: 542
• Identity: 118/542 - (21%)
• Similarity: 204/542 - (37%)
• Gaps: 148/542 - (27%)

  Fly    51 HFIDIVTPIYEKFKG-NGAPFAG--FFMMLRPVVLVTDLELAKQIL----IQDFANFEDRGM--- 105
            ::||.:..|.|...| ...||.|  |...|:|.      |..|::|    ..||..|  |.:
  Fly    23 NYIDHMAGIMEMIPGPTPYPFVGNLFQFGLKPA------EYPKKVLQYCRKYDFQGF--RSLVFL 79

  Fly   106 -YHNERDDP-------------LTGHLFRI------------DGPKWRPLRQKMSPTFTSAKMKY 144
             ||....||             ...||:..            .|.:|...::..:|.|..:.::.
  Fly    80 QYHMMLSDPAEIQNILSSSSLLYKEHLYSFLRPWLGDGLLTSSGARWLKHQKLYAPAFERSAIEG 144

  Fly   145 MFPTVCEVGEELTQVCGELADNAMCGILEIGDLMARYTSDVIGRCAFGVECNGLRNPEAEF---- 205
            ....|...|.:..|....|:|..  .:.:..:|:|:.|.|::...|.|.:.:.|....::.
  Fly   145 YLRVVHRTGGQFVQKLDVLSDTQ--EVFDAQELVAKCTLDIVCENATGQDSSSLNGETSDLHGAI 207

  Fly   206 ----AIMGRRAFSERRHCKLVDGFIESFPEVARFLRMRQIHQDITDFYVGIVRETVKQREEQGIV 266
                .::..|.||          .::.|..:.|          :|.:|       :|||....::
  Fly   208 KDLCDVVQERTFS----------IVKRFDALFR----------LTSYY-------MKQRRALSLL 245

  Fly   267 RSD---------------------------FMNLLIEMKQRGELTIE-EMAAQAFIFFAAGFDTS 303
            ||:                           |:::|:..|..|::..| |:..:...|...|.|..
  Fly   246 RSELNRIISQRRHQLAAENTCQQGQPINKPFLDVLLTAKLDGKVLKEREIIEEVSTFIFTGHDPI 310

  Fly   304 ASTLGFALYELAKQPALQAKLREEIDQALRLHN--GEFTYDSMQELRYMELVIAETLRKYPILPQ 366
            |:.:.|.||.|::...:|.|..|| .:.:...|  ||.....:.::.|:||:|.||||.||.:|.
  Fly   311 AAAISFTLYTLSRHSEIQQKAAEE-QRRIFGENFAGEADLARLDQMHYLELIIRETLRLYPSVPL 374

  Fly   367 LTRISRHLYAAKGDRHFYIEPGQMLLIPVYGIHHDPALYPEPHKFIPERFLADQLAQRPTA---- 427
            :.|.:|:.....|.:   :.....:::.:..:.::...:.:|..|.||||      :.||.
  Fly   375 IARTNRNPIDINGTK---VAKCTTVIMCLIAMGYNEKYFDDPCTFRPERF------ENPTGNVGI 430

  Fly   428 ---AWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCPRTD---------------PKIEF 474
               ..:||..|||.||..:|...|....|..|||  .|.:.|..|               |:.|:
  Fly   431 EAFKSVPFSAGPRRCIAEKFAMYQMKALLSQLLR--RFEILPAVDGLPPGINDHSREDCVPQSEY 493

  Fly   475 ---LKSNILLCPANGIYLKVQQ 493
               |...:.|...|||.:::::
  Fly   494 DPVLNIRVTLKSENGIQIRLRK 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	112/519 (22%)
Cyp4ad1	NP_610380.1	CYP4	73..511	CDD:410721	102/480 (21%)