Protein Alignment Cyp6a22 and Cyp6a2

DIOPT Version :9

• Sequence 1: NP_001286431.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Alignment Length: 505
• Identity: 230/505 - (45%)
• Similarity: 331/505 - (65%)
• Gaps: 15/505 - (2%)

  Fly     4 VVALLLIALA--VGFWFVRTRYSYWTRRGIGSEPARFPVGNMEGFRKNKHFIDIVTPIYEKFKGN 66
            |:..||||::  :.:.:.| .::||.|||:..:......|||.|||||:...|.....|.|::.:
  Fly     3 VLIYLLIAISSLLAYLYHR-NFNYWNRRGVPHDAPHPLYGNMVGFRKNRVMHDFFYDYYNKYRKS 66

  Fly    67 GAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTGHLFRIDGPKWRPLRQ 131
            |.||.||:.:.:|...:.|.:|||.|||:||:||.|||.:||.||||||.|||.:||.||:.:||
  Fly    67 GFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPLTQHLFNLDGKKWKDMRQ 131

  Fly   132 KMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCG-ILEIGDLMARYTSDVIGRCAFGVEC 195
            :::|||||.|||:|||||.:|.||..:|..|....|..| :|||.:||||:|:||||.||||:||
  Fly   132 RLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIKELMARFTTDVIGTCAFGIEC 196

  Fly   196 NGLRNPEAEFAIMGRRAFSERRHCKLVDGFIESFPEVARFLRMRQIHQDITDFYVGIVRETVKQR 260
            |.||.|.::|..||::.|::.||.||:..|:.|||::|..||||.:.:|:..|::.:|.:|:..|
  Fly   197 NTLRTPVSDFRTMGQKVFTDMRHGKLLTMFVFSFPKLASRLRMRMMPEDVHQFFMRLVNDTIALR 261

  Fly   261 EEQGIVRSDFMNLLIEMKQRGELTIE-----------EMAAQAFIFFAAGFDTSASTLGFALYEL 314
            |.:...|:||||||||:||:|.:|::           |:|||.|:|:.|||:||:||:.:.||||
  Fly   262 ERENFKRNDFMNLLIELKQKGRVTLDNGEVIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYEL 326

  Fly   315 AKQPALQAKLREEIDQALRLHNGEFTYDSMQELRYMELVIAETLRKYPILPQLTRISRHLYAAKG 379
            |:...:|.:||.||...|....|:.||:|::.:.|:..||:||||.|.::|.|.|.:.:.|...|
  Fly   327 AQNQDIQDRLRNEIQTVLEEQEGQLTYESIKAMTYLNQVISETLRLYTLVPHLERKALNDYVVPG 391

  Fly   380 DRHFYIEPGQMLLIPVYGIHHDPALYPEPHKFIPERFLADQLAQRPTAAWLPFGDGPRNCIGMRF 444
            .....||.|..::||....|.|..|||.|..|.||||..:::|.|.:..||||||||||||||||
  Fly   392 HEKLVIEKGTQVIIPACAYHRDEDLYPNPETFDPERFSPEKVAARESVEWLPFGDGPRNCIGMRF 456

  Fly   445 GKMQTTIGLVSLLRNFHFSVCPRTDPKIEFLKSNILLCPANGIYLKVQQL 494
            |:||..|||..::..|..|||..|:..:::...:|:|....||||:|:::
  Fly   457 GQMQARIGLAQIISRFRVSVCDTTEIPLKYSPMSIVLGTVGGIYLRVERI 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_001286431.1	p450	35..491	CDD:278495	218/467 (47%)
Cyp6a2	NP_523628.1	p450	36..502	CDD:278495	217/465 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471809
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	1	1.000	-	-		H130979
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	11	10.900